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Summary Expression Phenotypes Gene Literature (168) GO Terms (2) Nucleotides (27) Proteins (10) Interactants (263) Wiki
XB--478174

Papers associated with slc5a1.2



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How drugs interact with transporters: SGLT1 as a model., Loo DD, Hirayama BA, Sala-Rabanal M, Wright EM., J Membr Biol. May 1, 2008; 223 (2): 87-106.

A perchlorate sensitive iodide transporter in frogs., Carr DL, Carr JA, Willis RE, Pressley TA., Gen Comp Endocrinol. March 1, 2008; 156 (1): 9-14.      

Patterning the embryonic kidney: BMP signaling mediates the differentiation of the pronephric tubules and duct in Xenopus laevis., Bracken CM, Mizeracka K, McLaughlin KA., Dev Dyn. January 1, 2008; 237 (1): 132-44.          

Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        

SMIT2 mediates all myo-inositol uptake in apical membranes of rat small intestine., Aouameur R, Da Cal S, Bissonnette P, Coady MJ, Lapointe JY., Am J Physiol Gastrointest Liver Physiol. December 1, 2007; 293 (6): G1300-7.

Sodium-dependent reorganization of the sugar-binding site of SGLT1., Hirayama BA, Loo DD, Díez-Sampedro A, Leung DW, Meinild AK, Lai-Bing M, Turk E, Wright EM., Biochemistry. November 20, 2007; 46 (46): 13391-406.

Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity., Vernaleken A, Veyhl M, Gorboulev V, Kottra G, Palm D, Burckhardt BC, Burckhardt G, Pipkorn R, Beier N, van Amsterdam C, Koepsell H., J Biol Chem. September 28, 2007; 282 (39): 28501-13.

The mechanism of water transport in Na+-coupled glucose transporters expressed in Xenopus oocytes., Zeuthen T, Zeuthen E., Biophys J. August 15, 2007; 93 (4): 1413-6; discussion 1417-9.

Regulation of the Na(+), glucose cotransporter by PIKfyve and the serum and glucocorticoid inducible kinase SGK1., Shojaiefard M, Strutz-Seebohm N, Tavaré JM, Seebohm G, Lang F., Biochem Biophys Res Commun. August 10, 2007; 359 (4): 843-7.

Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake., Kottra G, Daniel H., J Pharmacol Exp Ther. August 1, 2007; 322 (2): 829-35.

Xenopus Bicaudal-C is required for the differentiation of the amphibian pronephros., Tran U, Pickney LM, Ozpolat BD, Wessely O., Dev Biol. July 1, 2007; 307 (1): 152-64.                  

Na+ -D-glucose cotransporter in the kidney of Leucoraja erinacea: molecular identification and intrarenal distribution., Althoff T, Hentschel H, Luig J, Schütz H, Kasch M, Kinne RK., Am J Physiol Regul Integr Comp Physiol. June 1, 2007; 292 (6): R2391-9.

Voltage-clamp fluorometry in the local environment of the C255-C511 disulfide bridge of the Na+/glucose cotransporter., Gagnon DG, Frindel C, Lapointe JY., Biophys J. April 1, 2007; 92 (7): 2403-11.

Inhibition of the intestinal glucose transporter GLUT2 by flavonoids., Kwon O, Eck P, Chen S, Corpe CP, Lee JH, Kruhlak M, Levine M., FASEB J. February 1, 2007; 21 (2): 366-77.

Effect of substrate on the pre-steady-state kinetics of the Na(+)/glucose cotransporter., Gagnon DG, Frindel C, Lapointe JY., Biophys J. January 15, 2007; 92 (2): 461-72.

RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1., Veyhl GJ., Am J Physiol Renal Physiol. December 1, 2006; 291 (6): F1213-23.

Conformational dynamics of hSGLT1 during Na+/glucose cotransport., Loo DD, Hirayama BA, Karakossian MH, Meinild AK, Wright EM., J Gen Physiol. December 1, 2006; 128 (6): 701-20.                            

Substrate specificity of a chimera made from Xenopus SGLT1-like protein and rabbit SGLT1., Nagata K, Hata Y., Biochim Biophys Acta. June 1, 2006; 1758 (6): 747-54.

Intracellular hypertonicity is responsible for water flux associated with Na+/glucose cotransport., Charron FM, Blanchard MG, Lapointe JY., Biophys J. May 15, 2006; 90 (10): 3546-54.

A glutamine to glutamate mutation at position 170 (Q170E) in the rabbit Na+/glucose cotransporter, rSGLT1, enhances binding affinity for Na+., Huntley SA, Krofchick D, Silverman M., Biochemistry. April 11, 2006; 45 (14): 4653-63.

Identification of a disulfide bridge linking the fourth and the seventh extracellular loops of the Na+/glucose cotransporter., Gagnon DG, Bissonnette P, Lapointe JY., J Gen Physiol. February 1, 2006; 127 (2): 145-58.                      

Water transport by Na+-coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution., Zeuthen T, Belhage B, Zeuthen E., J Physiol. February 1, 2006; 570 (Pt 3): 485-99.

Transport of d-galactose by the gastrointestinal tract of the locust, Locusta migratoria., Pascual I, Berjón A, Lostao MP, Barber A., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2006; 143 (1): 20-6.

Decreased intestinal glucose transport in the sgk3-knockout mouse., Sandu C, Rexhepaj R, Grahammer F, McCormick JA, Henke G, Palmada M, Nammi S, Lang U, Metzger M, Just L, Skutella T, Dawson K, Wang J, Pearce D, Lang F., Pflugers Arch. December 1, 2005; 451 (3): 437-44.

Membrane topology of loop 13-14 of the Na+/glucose cotransporter (SGLT1): a SCAM and fluorescent labelling study., Gagnon DG, Holt A, Bourgeois F, Wallendorff B, Coady MJ, Lapointe JY., Biochim Biophys Acta. June 30, 2005; 1712 (2): 173-84.

Role of actin in the cAMP-dependent activation of sodium/glucose cotransporter in renal epithelial cells., Ikari A, Harada H, Takagi K., Biochim Biophys Acta. June 1, 2005; 1711 (1): 20-4.

Kinetics of the reverse mode of the Na+/glucose cotransporter., Eskandari S, Wright EM, Loo DD., J Membr Biol. March 1, 2005; 204 (1): 23-32.

Determination of transport stoichiometry for two cation-coupled myo-inositol cotransporters: SMIT2 and HMIT., Bourgeois F, Coady MJ, Lapointe JY., J Physiol. March 1, 2005; 563 (Pt 2): 333-43.

Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter., Loo DD, Hirayama BA, Cha A, Bezanilla F, Wright EM., J Gen Physiol. January 1, 2005; 125 (1): 13-36.                                

Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454., Díez-Sampedro A, Loo DD, Wright EM, Zampighi GA, Hirayama BA., Biochemistry. October 19, 2004; 43 (41): 13175-84.

Transition states of the high-affinity rabbit Na(+)/glucose cotransporter SGLT1 as determined from measurement and analysis of voltage-dependent charge movements., Krofchick D, Huntley SA, Silverman M., Am J Physiol Cell Physiol. July 1, 2004; 287 (1): C46-54.

Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB., Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F., Obes Res. May 1, 2004; 12 (5): 862-70.

Glucose accumulation can account for the initial water flux triggered by Na+/glucose cotransport., Gagnon MP, Bissonnette P, Deslandes LM, Wallendorff B, Lapointe JY., Biophys J. January 1, 2004; 86 (1 Pt 1): 125-33.

Synthesis of 18F-fluoroalkyl-beta-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters., de Groot TJ, Veyhl M, Terwinghe C, Vanden Bempt V, Dupont P, Mortelmans L, Verbruggen AM, Bormans GM, Koepsell H., J Nucl Med. December 1, 2003; 44 (12): 1973-81.

Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C., Veyhl M, Wagner CA, Gorboulev V, Schmitt BM, Lang F, Koepsell H., J Membr Biol. November 1, 2003; 196 (1): 71-81.

Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes., Blasco T, Aramayona JJ, Alcalde AI, Catalán J, Sarasa M, Sorribas V., Am J Physiol Renal Physiol. October 1, 2003; 285 (4): F799-810.

A glucose sensor hiding in a family of transporters., Diez-Sampedro A, Hirayama BA, Osswald C, Gorboulev V, Baumgarten K, Volk C, Wright EM, Koepsell H., Proc Natl Acad Sci U S A. September 30, 2003; 100 (20): 11753-8.

Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters., Bormans GM, Van Oosterwyck G, De Groot TJ, Veyhl M, Mortelmans L, Verbruggen AM, Koepsell H., J Nucl Med. July 1, 2003; 44 (7): 1075-81.

Cloning and characterization of a novel Na+-dependent glucose transporter (NaGLT1) in rat kidney., Horiba N, Masuda S, Takeuchi A, Takeuchi D, Okuda M, Inui K., J Biol Chem. April 25, 2003; 278 (17): 14669-76.

Polyphenol-induced inhibition of the response of na(+)/glucose cotransporter expressed in Xenopus oocytes., Hossain SJ, Kato H, Aoshima H, Yokoyama T, Yamada M, Hara Y., J Agric Food Chem. August 28, 2002; 50 (18): 5215-9.

Mobility of ions, sugar, and water in the cytoplasm of Xenopus oocytes expressing Na(+)-coupled sugar transporters (SGLT1)., Zeuthen T, Zeuthen E, Klaerke DA., J Physiol. July 1, 2002; 542 (Pt 1): 71-87.

Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose., Song J, Kwon O, Chen S, Daruwala R, Eck P, Park JB, Levine M., J Biol Chem. May 3, 2002; 277 (18): 15252-60.

Controversy regarding the secondary active water transport hypothesis., Lapointe JY, Gagnon MP, Gagnon DG, Bissonnette P., Biochem Cell Biol. January 1, 2002; 80 (5): 525-33.

Molecular basis for glucose-galactose malabsorption., Wright EM, Turk E, Martin MG., Cell Biochem Biophys. January 1, 2002; 36 (2-3): 115-21.

Embryonic expression of Xenopus SGLT-1L, a novel member of the solute carrier family 5 (SLC5), is confined to tubules of the pronephric kidney., Eid SR, Terrettaz A, Nagata K, Brändli AW., Int J Dev Biol. January 1, 2002; 46 (1): 177-84.      

Residue 457 controls sugar binding and transport in the Na(+)/glucose cotransporter., Díez-Sampedro A, Wright EM, Hirayama BA., J Biol Chem. December 28, 2001; 276 (52): 49188-94.

The plasma membrane-associated protein RS1 decreases transcription of the transporter SGLT1 in confluent LLC-PK1 cells., Korn T, Kühlkamp T, Track C, Schatz I, Baumgarten K, Gorboulev V, Koepsell H., J Biol Chem. November 30, 2001; 276 (48): 45330-40.

Mapping the urea channel through the rabbit Na(+)-glucose cotransporter SGLT1., Panayotova-Heiermann M, Wright EM., J Physiol. September 1, 2001; 535 (Pt 2): 419-25.

Effects of gallium and mercury ions on transport systems., Moschèn, Schweizer K, Wagner CA, Geis-Gerstorfer J, Lang F., J Dent Res. August 1, 2001; 80 (8): 1753-7.

A missense mutation in the Na(+)/glucose cotransporter gene SGLT1 in a patient with congenital glucose-galactose malabsorption: normal trafficking but inactivation of the mutant protein., Kasahara M, Maeda M, Hayashi S, Mori Y, Abe T., Biochim Biophys Acta. May 31, 2001; 1536 (2-3): 141-7.

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