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Phospholipids as modulators of K(ATP) channels: distinct mechanisms for control of sensitivity to sulphonylureas, K(+) channel openers, and ATP. , Krauter T, Ruppersberg JP, Baukrowitz T., Mol Pharmacol. May 1, 2001; 59 (5): 1086-93.
Effects of mitiglinide (S 21403) on Kir6.2/ SUR1, Kir6.2/ SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel. , Reimann F, Proks P, Ashcroft FM., Br J Pharmacol. April 1, 2001; 132 (7): 1542-8.
Interaction of stilbene disulphonates with cloned K(ATP) channels. , Proks P, Jones P, Ashcroft FM., Br J Pharmacol. March 1, 2001; 132 (5): 973-82.
Direct interaction of Na-azide with the KATP channel. , Trapp S, Ashcroft FM., Br J Pharmacol. November 1, 2000; 131 (6): 1105-12.
Identification of molecular regions responsible for the membrane trafficking of Kir6.2. , Hough E, Beech DJ, Sivaprasadarao A., Pflugers Arch. July 1, 2000; 440 (3): 481-7.
Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide. , Tanabe K, Tucker SJ, Ashcroft FM, Proks P, Kioka N, Amachi T, Ueda K., Biochem Biophys Res Commun. June 7, 2000; 272 (2): 316-9.
Sensitivity of Kir6.2- SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazone. , McKay NG, Kinsella JM, Campbell CM, Ashford ML., Br J Pharmacol. June 1, 2000; 130 (4): 857-66.
Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/ SUR2A. , Gribble FM, Reimann F, Ashfield R, Ashcroft FM., Mol Pharmacol. June 1, 2000; 57 (6): 1256-61.
Altered functional properties of KATP channel conferred by a novel splice variant of SUR1. , Sakura H, Trapp S, Liss B, Ashcroft FM., J Physiol. December 1, 1999; 521 Pt 2 337-50.
In vitro mechanism of action on insulin release of S-22068, a new putative antidiabetic compound. , Le Brigand L, Virsolvy A, Manechez D, Godfroid JJ, Guardiola-Lemaître B, Gribble FM, Ashcroft FM, Bataille D., Br J Pharmacol. November 1, 1999; 128 (5): 1021-6.
The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP. , Reimann F, Ryder TJ, Tucker SJ, Ashcroft FM., J Physiol. November 1, 1999; 520 Pt 3 661-9.
Interaction of vanadate with the cloned beta cell K(ATP) channel. , Proks P, Ashfield R, Ashcroft FM., J Biol Chem. September 3, 1999; 274 (36): 25393-7.
PKA-mediated phosphorylation of the human K(ATP) channel: separate roles of Kir6.2 and SUR1 subunit phosphorylation. , Béguin P, Nagashima K, Nishimura M, Gonoi T, Seino S., EMBO J. September 1, 1999; 18 (17): 4722-32.
Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor. , Reimann F, Tucker SJ, Proks P, Ashcroft FM., J Physiol. July 15, 1999; 518 ( Pt 2) 325-36.
Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide. , Gribble FM, Ashcroft FM., Diabetologia. July 1, 1999; 42 (7): 845-8.
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. , Zerangue N, Schwappach B, Jan YN, Jan LY., Neuron. March 1, 1999; 22 (3): 537-48.
Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. , Tanabe K, Tucker SJ, Matsuo M, Proks P, Ashcroft FM, Seino S, Amachi T, Ueda K., J Biol Chem. February 12, 1999; 274 (7): 3931-3.
A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland. , Otonkoski T, Ammälä C, Huopio H, Cote GJ, Chapman J, Cosgrove K, Ashfield R, Huang E, Komulainen J, Ashcroft FM, Dunne MJ, Kere J, Thomas PM., Diabetes. February 1, 1999; 48 (2): 408-15.
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP. , Proks P, Gribble FM, Adhikari R, Tucker SJ, Ashcroft FM., J Physiol. January 1, 1999; 514 ( Pt 1) 19-25.
KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. , Drain P, Li L, Wang J ., Proc Natl Acad Sci U S A. November 10, 1998; 95 (23): 13953-8.
Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA. , Gribble FM, Proks P, Corkey BE, Ashcroft FM., J Biol Chem. October 9, 1998; 273 (41): 26383-7.
Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP. , Trapp S, Proks P, Tucker SJ, Ashcroft FM., J Gen Physiol. September 1, 1998; 112 (3): 333-49.
Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification. , Trapp S, Tucker SJ, Ashcroft FM., J Gen Physiol. September 1, 1998; 112 (3): 325-32.
MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. , Gribble FM, Tucker SJ, Haug T, Ashcroft FM., Proc Natl Acad Sci U S A. June 9, 1998; 95 (12): 7185-90.
Phentolamine block of KATP channels is mediated by Kir6.2. , Proks P, Ashcroft FM., Proc Natl Acad Sci U S A. October 14, 1997; 94 (21): 11716-20.
The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation. , Gribble FM, Tucker SJ, Ashcroft FM., J Physiol. October 1, 1997; 504 ( Pt 1) 35-45.
Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits. , Trapp S, Tucker SJ, Ashcroft FM., Proc Natl Acad Sci U S A. August 5, 1997; 94 (16): 8872-7.
Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. , Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM., Nature. May 8, 1997; 387 (6629): 179-83.
Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes. , Gribble FM, Ashfield R, Ammälä C, Ashcroft FM., J Physiol. January 1, 1997; 498 ( Pt 1) 87-98.
Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro. , Sakura H, Wat N, Horton V, Millns H, Turner RC, Ashcroft FM., Diabetologia. October 1, 1996; 39 (10): 1233-6.
Molecular site for nucleotide binding on an ATP-sensitive renal K+ channel (ROMK2). , McNicholas CM, Yang Y , Giebisch G, Hebert SC., Am J Physiol. August 1, 1996; 271 (2 Pt 2): F275-85.
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. , McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME., Proc Natl Acad Sci U S A. July 23, 1996; 93 (15): 8083-8.