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Summary Expression Phenotypes Gene Literature (197) GO Terms (5) Nucleotides (130) Proteins (44) Interactants (1264) Wiki
XB--481643

Papers associated with dkk1



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Novel functions of Noggin proteins: inhibition of Activin/Nodal and Wnt signaling., Bayramov AV, Eroshkin FM, Martynova NY, Ermakova GV, Solovieva EA, Zaraisky AG., Development. December 1, 2011; 138 (24): 5345-56.              

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways., Nalesso G, Sherwood J, Bertrand J, Pap T, Ramachandran M, De Bari C, Pitzalis C, Dell'accio F., J Cell Biol. May 2, 2011; 193 (3): 551-64.              

Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis., Ohkawara B, Glinka A, Niehrs C., Dev Cell. March 15, 2011; 20 (3): 303-14.                        

SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos., Wu MY, Ramel MC, Howell M, Hill CS., PLoS Biol. February 15, 2011; 9 (2): e1000593.                              

Different requirement for Wnt/β-catenin signaling in limb regeneration of larval and adult Xenopus., Yokoyama H, Maruoka T, Ochi H, Aruga A, Ohgo S, Ogino H, Tamura K, Tamura K., PLoS One. January 1, 2011; 6 (7): e21721.                

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart., Puskaric S, Schmitteckert S, Mori AD, Glaser A, Schneider KU, Bruneau BG, Blaschke RJ, Steinbeisser H, Rappold G., Hum Mol Genet. December 1, 2010; 19 (23): 4625-33.            

Anterior neural development requires Del1, a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway., Takai A, Inomata H, Arakawa A, Yakura R, Matsuo-Takasaki M, Sasai Y., Development. October 1, 2010; 137 (19): 3293-302.            

Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo., Tran HT, Sekkali B, Van Imschoot G, Janssens S, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.                                                

Evolutionary origin of the Otx2 enhancer for its expression in visceral endoderm., Kurokawa D, Ohmura T, Ogino H, Takeuchi M, Inoue A, Inoue F, Suda Y, Aizawa S., Dev Biol. June 1, 2010; 342 (1): 110-20.                

Mesodermal Wnt signaling organizes the neural plate via Meis3., Elkouby YM, Elias S, Casey ES, Blythe SA, Tsabar N, Klein PS, Root H, Liu KJ, Liu KJ, Frank D., Development. May 1, 2010; 137 (9): 1531-41.        

Identification and expression of ventrally associated leucine-zipper (VAL) in Xenopus embryo., Saito Y, Takahashi Y, Izutsu Y, Maeno M., Int J Dev Biol. January 1, 2010; 54 (1): 203-8.                

Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling., Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.                

Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis., Gessert S, Kühl M., Dev Biol. October 15, 2009; 334 (2): 395-408.          

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity., Tao H, Suzuki M, Kiyonari H, Abe T, Sasaoka T, Ueno N., Proc Natl Acad Sci U S A. August 25, 2009; 106 (34): 14426-31.      

Wnt/beta-catenin signaling: components, mechanisms, and diseases., MacDonald BT, Tamai K, He X., Dev Cell. July 1, 2009; 17 (1): 9-26.          

Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos., Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KW, Niehrs C., PLoS One. May 29, 2009; 4 (5): e5742.              

The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth., Dickinson AJ, Sive HL., Development. April 1, 2009; 136 (7): 1071-81.                                      

Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction., Steventon B, Araya C, Linker C, Kuriyama S, Mayor R., Development. March 1, 2009; 136 (5): 771-9.        

Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm., Hong CS, Park BY, Saint-Jeannet JP., Development. December 1, 2008; 135 (23): 3903-10.          

A novel activity of the Dickkopf-1 amino terminal domain promotes axial and heart development independently of canonical Wnt inhibition., Korol O, Gupta RW, Mercola M., Dev Biol. December 1, 2008; 324 (1): 131-8.

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling., Li Y, Rankin SA, Rankin SA, Sinner D, Kenny AP, Krieg PA, Zorn AM., Genes Dev. November 1, 2008; 22 (21): 3050-63.                        

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation., Cha SW, Tadjuidje E, Tao Q, Tao Q, Wylie C, Heasman J., Development. November 1, 2008; 135 (22): 3719-29.        

The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development., Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C., Development. November 1, 2008; 135 (22): 3655-64.                

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.        

Integrating positional information at the level of Smad1/5/8., Eivers E, Fuentealba LC, De Robertis EM., Curr Opin Genet Dev. August 1, 2008; 18 (4): 304-10.

Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling., Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A., Dev Cell. July 1, 2008; 15 (1): 37-48.

Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix., Zhang C, Cho K, Huang Y, Lyons JP, Zhou X, Sinha K, McCrea PD, de Crombrugghe B., Proc Natl Acad Sci U S A. May 13, 2008; 105 (19): 6936-41.  

Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration., Lin G, Slack JM., Dev Biol. April 15, 2008; 316 (2): 323-35.              

The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology., Nakamura T, Nakamura T, Matsumoto K., J Cell Mol Med. April 1, 2008; 12 (2): 391-408.          

MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling., David R, Brenner C, Stieber J, Schwarz F, Brunner S, Vollmer M, Mentele E, Müller-Höcker J, Kitajima S, Lickert H, Rupp R, Franz WM., Nat Cell Biol. March 1, 2008; 10 (3): 338-45.

Context-dependent activation or inhibition of Wnt-beta-catenin signaling by Kremen., Cselenyi CS, Lee E, Lee E., Sci Signal. February 26, 2008; 1 (8): pe10.

Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S, Niehrs C., Differentiation. December 1, 2007; 75 (10): 957-67.            

Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling., Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C., Development. December 1, 2007; 134 (23): 4255-63.      

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM., Cell. November 30, 2007; 131 (5): 980-93.      

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells., Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Rankin S, Lin SC, Jonatan D, Zorn AM, Wells JM., Mol Cell Biol. November 1, 2007; 27 (22): 7802-15.                

Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm., Carmona-Fontaine C, Acuña G, Ellwanger K, Niehrs C, Mayor R., Dev Biol. September 15, 2007; 309 (2): 208-21.              

Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration., Yokoyama H, Ogino H, Stoick-Cooper CL, Grainger RM, Moon RT., Dev Biol. June 1, 2007; 306 (1): 170-8.        

Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development., McLin VA, Rankin SA, Zorn AM., Development. June 1, 2007; 134 (12): 2207-17.            

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling., Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X., J Biol Chem. May 25, 2007; 282 (21): 15903-11.  

Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M, Sauka-Spengler T, Nicolle D, Le-Mentec C, Lallemand Y, Da Silva C, Plouhinec JL, Robert B, Wincker P, Shi DL, Mazan S., PLoS One. April 18, 2007; 2 (4): e374.              

Wnt/beta-catenin signaling controls Mespo expression to regulate segmentation during Xenopus somitogenesis., Wang J, Li S, Chen Y, Chen Y, Ding X., Dev Biol. April 15, 2007; 304 (2): 836-47.                    

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        

Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek., Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C, Houart C., Genes Dev. February 15, 2007; 21 (4): 465-80.

Wnt/beta-catenin signaling regulates vertebrate limb regeneration., Kawakami Y, Rodriguez Esteban C, Raya M, Kawakami H, Martí M, Dubova I, Izpisúa Belmonte JC., Genes Dev. December 1, 2006; 20 (23): 3232-7.    

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1., He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.

Characterization of myeloid cells derived from the anterior ventral mesoderm in the Xenopus laevis embryo., Tashiro S, Sedohara A, Asashima M, Izutsu Y, Maéno M., Dev Growth Differ. October 1, 2006; 48 (8): 499-512.                    

Embryonic heart induction., Foley AC, Gupta RW, Guzzo RM, Korol O, Mercola M., Ann N Y Acad Sci. October 1, 2006; 1080 85-96.

FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development., Urban AE, Zhou X, Zhou X, Ungos JM, Raible DW, Altmann CR, Vize PD., Dev Biol. September 1, 2006; 297 (1): 103-17.                    

Expression of Dickkopf genes is strongly reduced in malignant melanoma., Kuphal S, Lodermeyer S, Bataille F, Schuierer M, Hoang BH, Bosserhoff AK., Oncogene. August 17, 2006; 25 (36): 5027-36.

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