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Summary Expression Phenotypes Gene Literature (204) GO Terms (4) Nucleotides (291) Proteins (56) Interactants (824) Wiki
XB-GENEPAGE-1001989

Papers associated with cdk2



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Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2., Paris J, Le Guellec R, Couturier A, Le Guellec K, Omilli F, Camonis J, MacNeill S, Philippe M., Proc Natl Acad Sci U S A. February 1, 1991; 88 (3): 1039-43.

Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein., Le Guellec R, Paris J, Couturier A, Roghi C, Philippe M., Mol Cell Biol. June 1, 1991; 11 (6): 3395-8.

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1., Elledge SJ, Spottswood MR., EMBO J. September 1, 1991; 10 (9): 2653-9.

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase., Tsai LH, Harlow E, Meyerson M., Nature. September 12, 1991; 353 (6340): 174-7.

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family., Koff A, Cross F, Fisher A, Schumacher J, Leguellec K, Philippe M, Roberts JM., Cell. September 20, 1991; 66 (6): 1217-28.

Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation., Ninomiya-Tsuji J, Nomoto S, Yasuda H, Reed SI, Matsumoto K., Proc Natl Acad Sci U S A. October 15, 1991; 88 (20): 9006-10.

A cdc2-related kinase oscillates in the cell cycle independently of cyclins G2/M and cdc2., Gabrielli BG, Roy LM, Gautier J, Philippe M, Maller JL., J Biol Chem. January 25, 1992; 267 (3): 1969-75.

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle., Elledge SJ, Richman R, Hall FL, Williams RT, Lodgson N, Harper JW., Proc Natl Acad Sci U S A. April 1, 1992; 89 (7): 2907-11.

Isolation and characterization of goldfish cdk2, a cognate variant of the cell cycle regulator cdc2., Hirai T, Yamashita M, Yoshikuni M, Tokumoto T, Kajiura H, Sakai N, Nagahama Y., Dev Biol. July 1, 1992; 152 (1): 113-20.

Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2., Devault A, Fesquet D, Cavadore JC, Garrigues AM, Labbé JC, Lorca T, Picard A, Philippe M, Dorée M., J Cell Biol. September 1, 1992; 118 (5): 1109-20.

Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex., Gabrielli BG, Lee MS, Walker DH, Piwnica-Worms H, Maller JL., J Biol Chem. September 5, 1992; 267 (25): 18040-6.

Phosphorylation independent activation of human cyclin-dependent kinase 2 by cyclin A in vitro., Connell-Crowley L, Solomon MJ, Wei N, Harper JW., Mol Biol Cell. January 1, 1993; 4 (1): 79-92.

Requirement for Cdk2 in cytostatic factor-mediated metaphase II arrest., Gabrielli BG, Roy LM, Maller JL., Science. March 19, 1993; 259 (5102): 1766-9.

Cloning of the Eh cdc2 gene from Entamoeba histolytica encoding a protein kinase p34cdc2 homologue., Lohia A, Samuelson J., Gene. May 30, 1993; 127 (2): 203-7.

The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues., Fesquet D, Labbé JC, Derancourt J, Capony JP, Galas S, Girard F, Lorca T, Shuttleworth J, Dorée M, Cavadore JC., EMBO J. August 1, 1993; 12 (8): 3111-21.

Distinct roles of cdk2 and cdc2 in RP-A phosphorylation during the cell cycle., Fang F, Newport JW., J Cell Sci. November 1, 1993; 106 ( Pt 3) 983-94.

Molecular cloning and identification of two types of hamster cyclin-dependent kinases: cdk2 and cdk2L., Noguchi E, Sekiguchi T, Yamashita K, Nishimoto T., Biochem Biophys Res Commun. December 30, 1993; 197 (3): 1524-9.

Study of the higher eukaryotic gene function CDK2 using fission yeast., Paris J, Leplatois P, Nurse P., J Cell Sci. March 1, 1994; 107 ( Pt 3) 615-23.

Molecular cloning of the human CAK1 gene encoding a cyclin-dependent kinase-activating kinase., Wu L, Yee A, Liu L, Carbonaro-Hall D, Venkatesan N, Tolo VT, Hall FL., Oncogene. July 1, 1994; 9 (7): 2089-96.

E2F and its developmental regulation in Xenopus laevis., Philpott A, Friend SH., Mol Cell Biol. July 1, 1994; 14 (7): 5000-9.

Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts., Adachi Y, Laemmli UK., EMBO J. September 1, 1994; 13 (17): 4153-64.

Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development., Stebbins-Boaz B, Richter JD., Mol Cell Biol. September 1, 1994; 14 (9): 5870-80.

Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15., Poon RY, Yamashita K, Howell M, Ershler MA, Belyavsky A, Hunt T., J Cell Sci. October 1, 1994; 107 ( Pt 10) 2789-99.

Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases., Strausfeld UP, Howell M, Rempel R, Maller JL, Hunt T, Blow JJ., Curr Biol. October 1, 1994; 4 (10): 876-83.

Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase., Matsuoka M, Kato JY, Fisher RP, Morgan DO, Sherr CJ., Mol Cell Biol. November 1, 1994; 14 (11): 7265-75.

Cloning of the Xenopus laevis cdk2 promoter and functional analysis in oocytes and during early development., Olive M, Thézé N, Philippe M, Le Pennec JP, Lerivray H., Gene. December 30, 1994; 151 (1-2): 81-8.

Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases., Abraham RT, Acquarone M, Andersen A, Asensi A, Bellé R, Berger F, Bergounioux C, Brunn G, Buquet-Fagot C, Fagot D., Biol Cell. January 1, 1995; 83 (2-3): 105-20.

Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity., Izumi T, Maller JL., Mol Biol Cell. February 1, 1995; 6 (2): 215-26.

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA., Chen J, Jackson PK, Kirschner MW, Dutta A., Nature. March 23, 1995; 374 (6520): 386-8.

Maternal Xenopus Cdk2-cyclin E complexes function during meiotic and early embryonic cell cycles that lack a G1 phase., Rempel RE, Sleight SB, Maller JL., J Biol Chem. March 24, 1995; 270 (12): 6843-55.

An analysis of the regulation of DNA synthesis by cdk2, Cip1, and licensing factor., Yan H, Newport J., J Cell Biol. April 1, 1995; 129 (1): 1-15.

Both cdc2 and cdk2 promote S phase initiation in Xenopus egg extracts., Chevalier S, Tassan JP, Cox R, Philippe M, Ford C., J Cell Sci. May 1, 1995; 108 ( Pt 5) 1831-41.

Molecular cloning and immunological analysis of goldfish cyclin A during oocyte maturation., Katsu Y, Yamashita M, Hirai T, Tokumoto T, Kajiura H, Nagahama Y., Dev Biol. August 1, 1995; 170 (2): 616-25.

Early events in DNA replication require cyclin E and are blocked by p21CIP1., Jackson PK, Chevalier S, Philippe M, Kirschner MW., J Cell Biol. August 1, 1995; 130 (4): 755-69.

Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1., Su JY, Rempel RE, Erikson E, Maller JL., Proc Natl Acad Sci U S A. October 24, 1995; 92 (22): 10187-91.

Identification of a cdk-activating kinase in fission yeast., Buck V, Russell P, Millar JB., EMBO J. December 15, 1995; 14 (24): 6173-83.

Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity., Guadagno TM, Newport JW., Cell. January 12, 1996; 84 (1): 73-82.

In vivo regulation of the early embryonic cell cycle in Xenopus., Hartley RS, Rempel RE, Maller JL., Dev Biol. February 1, 1996; 173 (2): 408-19.

Cell cycle control by Xenopus p28Kix1, a developmentally regulated inhibitor of cyclin-dependent kinases., Shou W, Dunphy WG., Mol Biol Cell. March 1, 1996; 7 (3): 457-69.

CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus., Stebbins-Boaz B, Hake LE, Richter JD., EMBO J. May 15, 1996; 15 (10): 2582-92.

Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts., Strausfeld UP, Howell M, Descombes P, Chevalier S, Rempel RE, Adamczewski J, Maller JL, Hunt T, Blow JJ., J Cell Sci. June 1, 1996; 109 ( Pt 6) 1555-63.

Xenopus cyclin E, a nuclear phosphoprotein, accumulates when oocytes gain the ability to initiate DNA replication., Chevalier S, Couturier A, Chartrain I, Le Guellec R, Beckhelling C, Le Guellec K, Philippe M, Ford CC., J Cell Sci. June 1, 1996; 109 ( Pt 6) 1173-84.

Nuclear proteins of quiescent Xenopus laevis cells inhibit DNA replication in intact and permeabilized nuclei., Fang J, Benbow RM., J Cell Biol. June 1, 1996; 133 (5): 955-69.

Cyclin-binding motifs are essential for the function of p21CIP1., Chen J, Saha P, Kornbluth S, Dynlacht BD, Dutta A., Mol Cell Biol. September 1, 1996; 16 (9): 4673-82.

A predictive scale for evaluating cyclin-dependent kinase substrates. A comparison of p34cdc2 and p33cdk2., Holmes JK, Solomon MJ., J Biol Chem. October 11, 1996; 271 (41): 25240-6.

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5., Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ, Inagaki N, Inagaki M, Delcros JG, Moulinoux JP., Eur J Biochem. January 15, 1997; 243 (1-2): 527-36.

Identification of functional domains in the neuronal Cdk5 activator protein., Poon RY, Lew J, Hunter T., J Biol Chem. February 28, 1997; 272 (9): 5703-8.

Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines., Yang R, Morosetti R, Koeffler HP., Cancer Res. March 1, 1997; 57 (5): 913-20.

A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle., Hua XH, Yan H, Newport J., J Cell Biol. April 7, 1997; 137 (1): 183-92.            

Ionizing radiation induces apoptosis and elevates cyclin A1-Cdk2 activity before but not after the midblastula transition in Xenopus., Anderson JA, Lewellyn AL, Maller JL., Mol Biol Cell. July 1, 1997; 8 (7): 1195-206.                  

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