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Summary Expression Gene Literature (97) GO Terms (10) Nucleotides (71) Proteins (30) Interactants (123) Wiki

Papers associated with slc1a1

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Primary structure and functional characterization of a high-affinity glutamate transporter., Kanai Y, Hediger MA., Nature. December 3, 1992; 360 (6403): 467-71.

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex., Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG., J Neurosci. September 1, 1994; 14 (9): 5559-69.

Mammalian ion-coupled solute transporters., Hediger MA, Kanai Y, You G, Nussberger S., J Physiol. January 1, 1995; 482 7S-17S.

Electrogenic properties of the epithelial and neuronal high affinity glutamate transporter., Kanai Y, Nussberger S, Romero MF, Boron WF, Hebert SC, Hediger MA., J Biol Chem. July 14, 1995; 270 (28): 16561-8.

Functional analysis of the high affinity, Na(+)-dependent glutamate transporter GLAST-1 by site-directed mutagenesis., Conradt M, Stoffel W., J Biol Chem. October 20, 1995; 270 (42): 25207-12.

Nonradioactive monitoring of organic and inorganic solute transport into single Xenopus oocytes by capillary zone electrophoresis., Nussberger S, Foret F, Hebert SC, Karger BL, Hediger MA., Biophys J. February 1, 1996; 70 (2): 998-1005.

Comparison of Na+-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1)., Dowd LA, Coyle AJ, Rothstein JD, Pritchett DB, Robinson MB., Mol Pharmacol. March 1, 1996; 49 (3): 465-73.

Induction of high affinity glutamate transport activity by amino acid deprivation in renal epithelial cells does not involve an increase in the amount of transporter protein., Nicholson B, McGivan JD., J Biol Chem. May 24, 1996; 271 (21): 12159-64.

Interaction of L-cysteine with a human excitatory amino acid transporter., Zerangue N, Kavanaugh MP., J Physiol. June 1, 1996; 493 ( Pt 2) 419-23.

Flux coupling in a neuronal glutamate transporter., Zerangue N, Kavanaugh MP., Nature. October 17, 1996; 383 (6601): 634-7.

Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis., Castagna M, Shayakul C, Trotti D, Sacchi VF, Harvey WR, Hediger MA., J Exp Biol. January 1, 1997; 200 (Pt 2): 269-86.

Differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1., Trotti D, Nussberger S, Volterra A, Hediger MA., Eur J Neurosci. October 1, 1997; 9 (10): 2207-12.

Effect of benzodiazepines on the epithelial and neuronal high-affinity glutamate transporter EAAC1., Palmada M, Böhmer C, Centelles JJ, Kinne RK., J Neurochem. December 1, 1999; 73 (6): 2389-96.

Differentiation of substrate and nonsubstrate inhibitors of the high-affinity, sodium-dependent glutamate transporters., Koch HP, Kavanaugh MP, Esslinger CS, Zerangue N, Humphrey JM, Amara SG, Chamberlin AR, Bridges RJ., Mol Pharmacol. December 1, 1999; 56 (6): 1095-104.

Pentameric assembly of a neuronal glutamate transporter., Eskandari S, Kreman M, Kavanaugh MP, Wright EM, Zampighi GA., Proc Natl Acad Sci U S A. July 18, 2000; 97 (15): 8641-6.

Functional significance of N- and C-terminus of the amino acid transporters EAAC1 and ASCT1: characterization of chimeric transporters., Li J, Fei J, Huang F, Guo LH, Schwarz W., Biochim Biophys Acta. August 25, 2000; 1467 (2): 338-46.

Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity., Trotti D, Aoki M, Pasinelli P, Berger UV, Danbolt NC, Brown RH, Hediger MA., J Biol Chem. January 5, 2001; 276 (1): 576-82.

Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems., Eliasof S, McIlvain HB, Petroski RE, Foster AC, Dunlop J., J Neurochem. April 1, 2001; 77 (2): 550-7.

Cloning and characterization of excitatory amino acid transporters GLT-1 and EAAC1 in canine brain., Sato K, Inaba M, Baba K, Tamahara S, Koshino I, Hikasa Y, Ono K, Kagota K., J Vet Med Sci. September 1, 2001; 63 (9): 997-1002.

Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters., Trotti D, Peng JB, Dunlop J, Hediger MA., Brain Res. September 28, 2001; 914 (1-2): 196-203.

Effects of threo-beta-hydroxyaspartate derivatives on excitatory amino acid transporters (EAAT4 and EAAT5)., Shigeri Y, Shimamoto K, Yasuda-Kamatani Y, Seal RP, Yumoto N, Nakajima T, Amara SG., J Neurochem. October 1, 2001; 79 (2): 297-302.

Effects of volatile anesthetics on glutamate transporter, excitatory amino acid transporter type 3: the role of protein kinase C., Do SH, Kamatchi GL, Washington JM, Zuo Z., Anesthesiology. June 1, 2002; 96 (6): 1492-7.

Cloning and expression of the mouse glomerular podoplanin homologue gp38P., Boucherot A, Schreiber R, Pavenstädt H, Kunzelmann K., Nephrol Dial Transplant. June 1, 2002; 17 (6): 978-84.

The effects of lidocaine on the activity of glutamate transporter EAAT3: the role of protein kinase C and phosphatidylinositol 3-kinase., Do SH, Fang HY, Ham BM, Zuo Z., Anesth Analg. November 1, 2002; 95 (5): 1263-8, table of contents.

Effects of propofol on the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes: the role of protein kinase C., Do SH, Ham BM, Zuo Z., Neurosci Lett. June 5, 2003; 343 (2): 113-6.

Effects of ethanol on the rat glutamate excitatory amino acid transporter type 3 expressed in Xenopus oocytes: role of protein kinase C and phosphatidylinositol 3-kinase., Kim JH, Lim YJ, Ro YJ, Min SW, Kim CS, Do SH, Kim YL, Zuo Z., Alcohol Clin Exp Res. October 1, 2003; 27 (10): 1548-53.

WAY-855 (3-amino-tricyclo[]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake., Dunlop J, Eliasof S, Stack G, McIlvain HB, Greenfield A, Kowal D, Petroski R, Carrick T., Br J Pharmacol. November 1, 2003; 140 (5): 839-46.

Modulation of Na(+),K(+) pumping and neurotransmitter uptake by beta-amyloid., Gu QB, Zhao JX, Fei J, Schwarz W., Neuroscience. January 1, 2004; 126 (1): 61-7.

Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1 [correction]., Schniepp R, Kohler K, Ladewig T, Guenther E, Henke G, Palmada M, Boehmer C, Rothstein JD, Bröer S, Lang F., Invest Ophthalmol Vis Sci. May 1, 2004; 45 (5): 1442-9.

Different functional roles of arginine residues 39 and 61 and tyrosine residue 98 in transport and channel mode of the glutamate transporter EAAC1., Zhu Y, Vasilets LA, Fei J, Guo L, Schwarz W., Biochim Biophys Acta. October 11, 2004; 1665 (1-2): 20-8.

Expression and transport function of the glutamate transporter EAAC1 in Xenopus oocytes is regulated by syntaxin 1A., Zhu Y, Fei J, Schwarz W., J Neurosci Res. February 15, 2005; 79 (4): 503-8.

Glutamate transporter type 3 attenuates the activation of N-methyl-D-aspartate receptors co-expressed in Xenopus oocytes., Zuo Z, Fang H., J Exp Biol. June 1, 2005; 208 (Pt 11): 2063-70.

Carbamazepine enhances the activity of glutamate transporter type 3 via phosphatidylinositol 3-kinase., Lee G, Huang Y, Washington JM, Briggs NW, Zuo Z., Epilepsy Res. August 1, 2005; 66 (1-3): 145-53.

Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2., Dunlop J, McIlvain HB, Carrick TA, Jow B, Lu Q, Kowal D, Lin S, Greenfield A, Grosanu C, Fan K, Petroski R, Williams J, Foster A, Butera J., Mol Pharmacol. October 1, 2005; 68 (4): 974-82.

Effects of chronic exposure to ethanol on glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement., Kim JH, Do SH, Kim YL, Zuo Z., Alcohol Clin Exp Res. November 1, 2005; 29 (11): 2046-52.

Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons., Meera P, Dodson PD, Karakossian MH, Otis TS., Neuropharmacology. November 1, 2005; 49 (6): 883-9.

The substituted aspartate analogue L-beta-threo-benzyl-aspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3., Esslinger CS, Agarwal S, Gerdes J, Wilson PA, Davis ES, Awes AN, O'Brien E, Mavencamp T, Koch HP, Poulsen DJ, Rhoderick JF, Chamberlin AR, Kavanaugh MP, Bridges RJ., Neuropharmacology. November 1, 2005; 49 (6): 850-61.

Effects of intravenous anesthetics on the activity of glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement., Yun JY, Kim JH, Kim HK, Lim YJ, Do SH, Zuo Z., Eur J Pharmacol. February 15, 2006; 531 (1-3): 133-9.

Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor., Xia P, Pei G, Schwarz W., Eur J Neurosci. July 1, 2006; 24 (1): 87-93.

Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin., Malakauskas SM, Quan H, Fields TA, McCall SJ, Yu MJ, Kourany WM, Frey CW, Le TH., Am J Physiol Renal Physiol. February 1, 2007; 292 (2): F533-44.

The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits., Koch HP, Brown RL, Larsson HP., J Neurosci. March 14, 2007; 27 (11): 2943-7.

The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits., Leary GP, Stone EF, Holley DC, Kavanaugh MP., J Neurosci. March 14, 2007; 27 (11): 2938-42.

Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter., Teichman S, Kanner BI., J Gen Physiol. June 1, 2007; 129 (6): 527-39.                    

Propofol reverses oxidative stress-attenuated glutamate transporter EAAT3 activity: evidence of protein kinase C involvement., Yun JY, Park KS, Kim JH, Do SH, Zuo Z., Eur J Pharmacol. June 22, 2007; 565 (1-3): 83-8.

Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3., Koch HP, Hubbard JM, Larsson HP., J Biol Chem. August 24, 2007; 282 (34): 24547-53.

Neuronal glutamate transporters vary in substrate transport rate but not in unitary anion channel conductance., Torres-Salazar D, Fahlke C., J Biol Chem. November 30, 2007; 282 (48): 34719-26.

Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        

Critical role of s465 in protein kinase C-increased rat glutamate transporter type 3 activity., Baik HJ, Huang Y, Washington JM, Zuo Z., Int J Neurosci. January 1, 2009; 119 (9): 1419-28.

Alphaxalone, a neurosteroid anaesthetic, increases the activity of the glutamate transporter type 3 expressed in Xenopus oocytes., Ryu J, Cheong IY, Do SH, Zuo Z., Eur J Pharmacol. January 5, 2009; 602 (1): 23-7.

Regulation of the Na(+)-coupled glutamate transporter EAAT3 by PIKfyve., Klaus F, Gehring EM, Zürn A, Laufer J, Lindner R, Strutz-Seebohm N, Tavaré JM, Rothstein JD, Boehmer C, Palmada M, Gruner I, Lang UE, Seebohm G, Lang F., Neurochem Int. May 1, 2009; 54 (5-6): 372-7.

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