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Summary Expression Phenotypes Gene Literature (21) GO Terms (11) Nucleotides (104) Proteins (64) Interactants (54) Wiki
XB-GENEPAGE-1014106

Papers associated with slc12a4



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WNK3 and WNK4 exhibit opposite sensitivity with respect to cell volume and intracellular chloride concentration., Pacheco-Alvarez D, Carrillo-Pérez DL, Mercado A, Leyva-Ríos K, Moreno E, Hernández-Mercado E, Castañeda-Bueno M, Vázquez N, Gamba G., Am J Physiol Cell Physiol. August 1, 2020; 319 (2): C371-C380.


Cryo-EM structures of the human cation-chloride cotransporter KCC1., Liu S, Chang S, Han B, Xu L, Zhang M, Zhao C, Yang W, Wang F, Li J, Delpire E, Ye S, Bai XC, Guo J., Science. October 25, 2019; 366 (6464): 505-508.


Cotransporter-mediated water transport underlying cerebrospinal fluid formation., Steffensen AB, Oernbo EK, Stoica A, Gerkau NJ, Barbuskaite D, Tritsaris K, Rose CR, MacAulay N., Nat Commun. June 4, 2018; 9 (1): 2167.              


With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters., Mercado A, de Los Heros P, Melo Z, Chávez-Canales M, Murillo-de-Ozores AR, Moreno E, Bazúa-Valenti S, Vázquez N, Hadchouel J, Gamba G., Am J Physiol Cell Physiol. July 1, 2016; 311 (1): C54-66.


Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics., Salin-Cantegrel A, Shekarabi M, Rasheed S, Charron FM, Laganière J, Gaudet R, Dion PA, Lapointe JY, Rouleau GA., PLoS One. May 15, 2013; 8 (5): e65294.            


WNK3 is a putative chloride-sensing kinase., Pacheco-Alvarez D, Gamba G., Cell Physiol Biochem. January 1, 2011; 28 (6): 1123-34.


Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter., Casula S, Zolotarev AS, Stuart-Tilley AK, Wilhelm S, Shmukler BE, Brugnara C, Alper SL., Blood Cells Mol Dis. January 1, 2009; 42 (3): 233-40.


The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2., Ferron L, Davies A, Page KM, Cox DJ, Leroy J, Waithe D, Butcher AJ, Sellaturay P, Bolsover S, Pratt WS, Moss FJ, Dolphin AC., J Neurosci. October 15, 2008; 28 (42): 10604-17.


Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters., Simard CF, Bergeron MJ, Frenette-Cotton R, Carpentier GA, Pelchat ME, Caron L, Isenring P., J Biol Chem. June 22, 2007; 282 (25): 18083-18093.


WNK4 kinase is a negative regulator of K+-Cl- cotransporters., Garzón-Muvdi T, Pacheco-Alvarez D, Gagnon KB, Vázquez N, Ponce-Coria J, Moreno E, Delpire E, Gamba G., Am J Physiol Renal Physiol. April 1, 2007; 292 (4): F1197-207.


WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway., de Los Heros P, Kahle KT, Rinehart J, Bobadilla NA, Vázquez N, San Cristobal P, Mount DB, Lifton RP, Hebert SC, Gamba G., Proc Natl Acad Sci U S A. February 7, 2006; 103 (6): 1976-81.


WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability., Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16783-8.


Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters., Bergeron MJ, Gagnon E, Wallendorff B, Lapointe JY, Isenring P., Am J Physiol Renal Physiol. July 1, 2003; 285 (1): F68-78.


Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter., Song L, Mercado A, Vázquez N, Xie Q, Desai R, George AL, Gamba G, Mount DB., Brain Res Mol Brain Res. June 30, 2002; 103 (1-2): 91-105.


Immunolocalization of potassium-chloride cotransporter polypeptides in rat exocrine glands., Roussa E, Shmukler BE, Wilhelm S, Casula S, Stuart-Tilley AK, Thévenod F, Alper SL., Histochem Cell Biol. April 1, 2002; 117 (4): 335-44.


A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity., Casula S, Shmukler BE, Wilhelm S, Stuart-Tilley AK, Su W, Chernova MN, Brugnara C, Alper SL., J Biol Chem. November 9, 2001; 276 (45): 41870-8.


Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes., Mercado A, de los Heros P, Vázquez N, Meade P, Mount DB, Gamba G., Am J Physiol Cell Physiol. August 1, 2001; 281 (2): C670-80.


Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4., Mercado A, Song L, Vazquez N, Mount DB, Gamba G., J Biol Chem. September 29, 2000; 275 (39): 30326-34.


Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue., Strange K, Singer TD, Morrison R, Delpire E., Am J Physiol Cell Physiol. September 1, 2000; 279 (3): C860-7.


Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation., Su W, Shmukler BE, Chernova MN, Stuart-Tilley AK, de Franceschi L, Brugnara C, Alper SL., Am J Physiol. November 1, 1999; 277 (5): C899-912.


Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family., Mount DB, Mercado A, Song L, Xu J, George AL, Delpire E, Gamba G., J Biol Chem. June 4, 1999; 274 (23): 16355-62.

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