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Summary Expression Phenotypes Gene Literature (216) GO Terms (8) Nucleotides (79) Proteins (54) Interactants (1104) Wiki
XB-GENEPAGE-1217287

Papers associated with wnt3a



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The molecular mechanisms underlying the regeneration process in the earthworm, Perionyx excavatus exhibit indications of apoptosis-induced compensatory proliferation (AICP)., Rajagopalan K, Christyraj JDS, Chelladurai KS, Christyraj JRSS, Das P, Roy A, Vrushali C, Chemmet NSM., In Vitro Cell Dev Biol Anim. March 1, 2024; 60 (3): 222-235.

R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  

ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation., Wang C, Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y, Qi X, Cai D, Mao B, Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H., EMBO Rep. February 1, 2024; 25 (2): 646-671.                                          

Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis., Azbazdar Y, Tejeda-Munoz N, Monka JC, Dayrit A, Binder G, Ozhan G, De Robertis EM., iScience. October 20, 2023; 26 (10): 108075.                

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax., Wang S, Shibata Y, Fu L, Tanizaki Y, Luu N, Bao L, Peng Z, Shi YB, Shi YB., Cell Biosci. February 23, 2023; 13 (1): 40.              

Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling., Hwang WY, Kostiuk V, González DP, Lusk CP, Khokha MK., Elife. October 27, 2022; 11               

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway., Predes D, Maia LA, Matias I, Araujo HPM, Soares C, Barros-Aragão FGQ, Oliveira LFS, Reis RR, Amado NG, Simas ABC, Mendes FA, Gomes FCA, Figueiredo CP, Abreu JG., Int J Mol Sci. October 11, 2022; 23 (20):                   

Cellular responses in the FGF10-mediated improvement of hindlimb regenerative capacity in Xenopus laevis revealed by single-cell transcriptomics., Yanagi N, Kato S, Fukazawa T, Kubo T., Dev Growth Differ. August 1, 2022; 64 (6): 266-278.      

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                

Analysis of the Expression Pattern of Cajal-Retzius Cell Markers in the Xenopus laevis Forebrain., Jiménez S, Moreno N., Brain Behav Evol. January 1, 2022; 96 (4-6): 263-282.

New Findings on LMO7 Transcripts, Proteins and Regulatory Regions in Human and Vertebrate Model Organisms and the Intracellular Distribution in Skeletal Muscle Cells., Gomes G, do Amaral MJ, Bagri KM, Vasconcellos LM, Almeida MDS, Alvares LE, Mermelstein C., Int J Mol Sci. November 28, 2021; 22 (23):                           

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH., Development. October 1, 2021; 148 (19):               

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK, Saint-Jeannet JP., Dev Biol. August 1, 2021; 476 200-208.            

A catenin of the plakophilin-subfamily, Pkp3, responds to canonical-Wnt pathway components and signals., Hong JY, Zapata J, Blackburn A, Baumert R, Bae SM, Ji H, Nam HJ, Miller RK, McCrea PD., Biochem Biophys Res Commun. July 23, 2021; 563 31-39.        

Rab7 is required for mesoderm patterning and gastrulation in Xenopus., Kreis J, Wielath FM, Vick P., Biol Open. July 15, 2021; 10 (7):                                           

Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification., Reis AH, Sokol SY., Sci Rep. June 28, 2021; 11 (1): 13433.            

Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs., Aztekin C, Hiscock TW, Gurdon J, Jullien J, Marioni J, Simons BD., Development. June 1, 2021; 148 (11):                                             

Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway., Wang H, Wang C, Wang C, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H., Development. May 15, 2021; 148 (10):                                           

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

FAM83F regulates canonical Wnt signalling through an interaction with CK1α., Dunbar K, Jones RA, Dingwell K, Macartney TJ, Smith JC, Sapkota GP., Life Sci Alliance. December 24, 2020; 4 (2):                                   

Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis., Lee H, Lee H, Ismail T, Kim Y, Chae S, Ryu HY, Lee DS, Kwon TK, Park TJ, Kwon T, Lee HS, Lee HS., Antioxidants (Basel). December 12, 2020; 9 (12):               

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM., Sci Rep. December 9, 2020; 10 (1): 21555.            

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains., Kim J, Han W, Park T, Kim EJ, Bang I, Lee HS, Lee HS, Jeong Y, Roh K, Kim J, Kim JS, Kang C, Seok C, Han JK, Choi HJ., Nat Commun. October 23, 2020; 11 (1): 5357.            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM., Cell Rep. July 28, 2020; 32 (4): 107973.                                      

MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88., Xu T, Pan L, Li L, Hu S, Zhou H, Yang C, Yang J, Li H, Liu Y, Meng X, Li J., J Cell Mol Med. July 1, 2020; 24 (13): 7127-7140.              

eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G., J Biol Chem. June 26, 2020; 295 (26): 8759-8774.          

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal., Mii Y, Takada S., Front Cell Dev Biol. January 1, 2020; 8 631.    

Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. January 1, 2020;                                       

The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation., Predes D, Oliveira LFS, Ferreira LSS, Maia LA, Delou JMA, Faletti A, Oliveira I, Amado NG, Reis AH, Fraga CAM, Kuster R, Mendes FA, Borges HL, Abreu JG., Cancers (Basel). December 7, 2019; 11 (12):             

Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Piprek RP, Damulewicz M, Tassan JP, Kloc M, Kubiak JZ., Dev Genes Evol. May 1, 2019; 229 (2-3): 53-72.        

Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)., Tuladhar R, Yarravarapu N, Ma Y, Zhang C, Herbert J, Kim J, Chen C, Lum L., J Biol Chem. April 19, 2019; 294 (16): 6273-6282.              

Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1., Harnoš J, Cañizal MCA, Jurásek M, Kumar J, Holler C, Schambony A, Hanáková K, Bernatík O, Zdráhal Z, Gömöryová K, Gybeľ T, Radaszkiewicz TW, Kravec M, Trantírek L, Ryneš J, Dave Z, Fernández-Llamazares AI, Vácha R, Tripsianes K, Hoffmann C, Bryja V., Nat Commun. April 18, 2019; 10 (1): 1804.                  

Non-acylated Wnts Can Promote Signaling., Speer KF, Sommer A, Tajer B, Mullins MC, Klein PS, Lemmon MA., Cell Rep. January 22, 2019; 26 (4): 875-883.e5.                  

Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling., Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC, Sapkota GP., Wellcome Open Res. January 1, 2019; 4 133.          

Assembly of protein complexes restricts diffusion of Wnt3a proteins., Takada R, Mii Y, Krayukhina E, Maruyama Y, Mio K, Sasaki Y, Shinkawa T, Pack CG, Sako Y, Sato C, Uchiyama S, Takada S., Commun Biol. October 10, 2018; 1 165.              

TMEM88 mediates inflammatory cytokines secretion by regulating JNK/P38 and canonical Wnt/β-catenin signaling pathway in LX-2 cells., Xu T, Pan LX, Ge YX, Li P, Meng XM, Huang C, Li J., Inflammopharmacology. October 1, 2018; 26 (5): 1339-1348.

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Regulation of neural crest development by the formin family protein Daam1., Ossipova O, Kerney R, Saint-Jeannet JP, Sokol SY., Genesis. June 1, 2018; 56 (6-7): e23108.              

Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling., Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E, Lee E., J Cell Sci. May 22, 2018; 131 (10):         

PAWS1 controls Wnt signalling through association with casein kinase 1α., Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC, Sapkota GP., EMBO Rep. April 1, 2018; 19 (4):                             

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.          

Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus., Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M., Nat Commun. December 7, 2017; 8 (1): 1973.                                                  

Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord., Steventon B, Martinez Arias A., Dev Biol. December 1, 2017; 432 (1): 3-13.

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

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