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Summary Expression Phenotypes Gene Literature (216) GO Terms (8) Nucleotides (79) Proteins (54) Interactants (1104) Wiki
XB--1217287

Papers associated with wnt3a (and Disease Ontology)



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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway., Predes D, Maia LA, Matias I, Araujo HPM, Soares C, Barros-Aragão FGQ, Oliveira LFS, Reis RR, Amado NG, Simas ABC, Mendes FA, Gomes FCA, Figueiredo CP, Abreu JG., Int J Mol Sci. October 11, 2022; 23 (20):                   

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH., Development. October 1, 2021; 148 (19):               

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK, Saint-Jeannet JP., Dev Biol. August 1, 2021; 476 200-208.            

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

FAK and WNT signaling: the meeting of two pathways in cancer and development., Fonar Y, Frank D., Anticancer Agents Med Chem. September 1, 2011; 11 (7): 600-6.

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria., Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL., Dev Cell. September 14, 2010; 19 (3): 413-25.  

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex., Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Brivanlou AH, Barres BA, Christiano AM., Nature. April 15, 2010; 464 (7291): 1043-7.      

Wnt/beta-catenin signaling: components, mechanisms, and diseases., MacDonald BT, Tamai K, He X., Dev Cell. July 1, 2009; 17 (1): 9-26.          

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity., Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.              

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