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Summary Expression Phenotypes Gene Literature (168) GO Terms (2) Nucleotides (27) Proteins (10) Interactants (263) Wiki
XB-GENEPAGE-478174

Papers associated with slc5a1.2



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Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter., Turk E, Zabel B, Mundlos S, Dyer J, Wright EM., Nature. March 28, 1991; 350 (6316): 354-6.

Cloning and functional expression of a mammalian Na+/nucleoside cotransporter. A member of the SGLT family., Pajor AM, Wright EM., J Biol Chem. February 25, 1992; 267 (6): 3557-60.

Molecular evidence for two renal Na+/glucose cotransporters., Pajor AM, Hirayama BA, Wright EM., Biochim Biophys Acta. April 29, 1992; 1106 (1): 216-20.

Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter., Wells RG, Pajor AM, Kanai Y, Turk E, Wright EM, Hediger MA., Am J Physiol. September 1, 1992; 263 (3 Pt 2): F459-65.

[Thirty years of research on congenital glucose and galactose malabsorption: from phenotype to genotype]., Desjeux JF, Wright EM., Bull Acad Natl Med. January 1, 1993; 177 (1): 125-31; discussion 132-5.

[30 years' work on congenital glucose and galactose malabsorption: from phenotype to genotype]., Desjeux JF, Wright EM., Ann Gastroenterol Hepatol (Paris). October 1, 1993; 29 (5): 263-6; discussion 266-8.

Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter., Veyhl M, Spangenberg J, Püschel B, Poppe R, Dekel C, Fritzsch G, Haase W, Koepsell H., J Biol Chem. November 25, 1993; 268 (33): 25041-53.

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose., Kanai Y, Lee WS, You G, Brown D, Hediger MA., J Clin Invest. January 1, 1994; 93 (1): 397-404.

The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression., Lee WS, Kanai Y, Wells RG, Hediger MA., J Biol Chem. April 22, 1994; 269 (16): 12032-9.

The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport., Kanai Y, Stelzner M, Nussberger S, Khawaja S, Hebert SC, Smith CP, Hediger MA., J Biol Chem. August 12, 1994; 269 (32): 20599-606.

Sodium/D-glucose cotransporter charge movements involve polar residues., Panayotova-Heiermann M, Loo DD, Lostao MP, Wright EM., J Biol Chem. August 19, 1994; 269 (33): 21016-20.

Protons drive sugar transport through the Na+/glucose cotransporter (SGLT1)., Hirayama BA, Loo DD, Wright EM., J Biol Chem. August 26, 1994; 269 (34): 21407-10.

SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation., Mackenzie B, Panayotova-Heiermann M, Loo DD, Lever JE, Wright EM., J Biol Chem. September 9, 1994; 269 (36): 22488-91.

Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions., Lostao MP, Hirayama BA, Loo DD, Wright EM., J Membr Biol. November 1, 1994; 142 (2): 161-70.

'Active' sugar transport in eukaryotes., Wright EM, Loo DD, Panayotova-Heiermann M, Lostao MP, Hirayama BH, Mackenzie B, Boorer K, Zampighi G., J Exp Biol. November 1, 1994; 196 197-212.

Mammalian ion-coupled solute transporters., Hediger MA, Kanai Y, You G, Nussberger S., J Physiol. January 1, 1995; 482 7S-17S.

Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes., Hager K, Hazama A, Kwon HM, Loo DD, Handler JS, Wright EM., J Membr Biol. January 1, 1995; 143 (2): 103-13.

Electrogenic properties of the epithelial and neuronal high affinity glutamate transporter., Kanai Y, Nussberger S, Romero MF, Boron WF, Hebert SC, Hediger MA., J Biol Chem. July 14, 1995; 270 (28): 16561-8.

A method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes., Zampighi GA, Kreman M, Boorer KJ, Loo DD, Bezanilla F, Chandy G, Hall JE, Wright EM., J Membr Biol. November 1, 1995; 148 (1): 65-78.

Kinetics of steady-state currents and charge movements associated with the rat Na+/glucose cotransporter., Panayotova-Heiermann M, Loo DD, Wright EM., J Biol Chem. November 10, 1995; 270 (45): 27099-105.

Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter., Chen XZ, Coady MJ, Jackson F, Berteloot A, Lapointe JY., Biophys J. December 1, 1995; 69 (6): 2405-14.

Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney., You G, Lee WS, Barros EJ, Kanai Y, Huo TL, Khawaja S, Wells RG, Nigam SK, Hediger MA., J Biol Chem. December 8, 1995; 270 (49): 29365-71.

Arginine-427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane., Lostao MP, Hirayama BA, Panayotova-Heiermann M, Sampogna SL, Bok D, Wright EM., FEBS Lett. December 18, 1995; 377 (2): 181-4.

Membrane topology of the human Na+/glucose cotransporter SGLT1., Turk E, Kerner CJ, Lostao MP, Wright EM., J Biol Chem. January 26, 1996; 271 (4): 1925-34.

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption., Martín MG, Turk E, Lostao MP, Kerner C, Wright EM., Nat Genet. February 1, 1996; 12 (2): 216-20.

Sugar binding to Na+/glucose cotransporters is determined by the carboxyl-terminal half of the protein., Panayotova-Heiermann M, Loo DD, Kong CT, Lever JE, Wright EM., J Biol Chem. April 26, 1996; 271 (17): 10029-34.

Kinetic and specificity differences between rat, human, and rabbit Na+-glucose cotransporters (SGLT-1)., Hirayama BA, Lostao MP, Panayotova-Heiermann M, Loo DD, Turk E, Wright EM., Am J Physiol. June 1, 1996; 270 (6 Pt 1): G919-26.

Regulation of Na+/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes., Hirsch JR, Loo DD, Wright EM., J Biol Chem. June 21, 1996; 271 (25): 14740-6.

The human gene of a protein that modifies Na(+)-D-glucose co-transport., Lambotte S, Veyhl M, Köhler M, Morrison-Shetlar AI, Kinne RK, Schmid M, Koepsell H., DNA Cell Biol. September 1, 1996; 15 (9): 769-77.

Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2., Mackenzie B, Loo DD, Panayotova-Heiermann M, Wright EM., J Biol Chem. December 20, 1996; 271 (51): 32678-83.

Regulation of Na+/glucose cotransporters., Wright EM, Hirsch JR, Loo DD, Zampighi GA., J Exp Biol. January 1, 1997; 200 (Pt 2): 287-93.

Presteady-state currents of the rabbit Na+/glucose cotransporter (SGLT1)., Hazama A, Loo DD, Wright EM., J Membr Biol. January 15, 1997; 155 (2): 175-86.

Cation effects on protein conformation and transport in the Na+/glucose cotransporter., Hirayama BA, Loo DD, Wright EM., J Biol Chem. January 24, 1997; 272 (4): 2110-5.

Compound missense mutations in the sodium/D-glucose cotransporter result in trafficking defects., Martín MG, Lostao MP, Turk E, Lam J, Kreman M, Wright EM., Gastroenterology. April 1, 1997; 112 (4): 1206-12.

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid., Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M., J Biol Chem. July 25, 1997; 272 (30): 18982-9.

Five transmembrane helices form the sugar pathway through the Na+/glucose cotransporter., Panayotova-Heiermann M, Eskandari S, Turk E, Zampighi GA, Wright EM., J Biol Chem. August 15, 1997; 272 (33): 20324-7.

Sodium leak pathway and substrate binding order in the Na+-glucose cotransporter., Chen XZ, Coady MJ, Jalal F, Wallendorff B, Lapointe JY., Biophys J. November 1, 1997; 73 (5): 2503-10.

Relationships between Na+/glucose cotransporter (SGLT1) currents and fluxes., Mackenzie B, Loo DD, Wright EM., J Membr Biol. March 15, 1998; 162 (2): 101-6.

Conformational changes couple Na+ and glucose transport., Loo DD, Hirayama BA, Gallardo EM, Lam JT, Turk E, Wright EM., Proc Natl Acad Sci U S A. June 23, 1998; 95 (13): 7789-94.

Structure and function of the Na+/glucose cotransporter., Wright EM, Loo DD, Panayotova-Heiermann M, Hirayama BA, Turk E, Eskandari S, Lam JT., Acta Physiol Scand Suppl. August 1, 1998; 643 257-64.

Cysteine scanning mutagenesis of the segment between putative transmembrane helices IV and V of the high affinity Na+/Glucose cotransporter SGLT1. Evidence that this region participates in the Na+ and voltage dependence of the transporter., Lo B, Silverman M., J Biol Chem. November 6, 1998; 273 (45): 29341-51.

Cloning and characterization of the transport modifier RS1 from rabbit which was previously assumed to be specific for Na+-D-glucose cotransport., Reinhardt J, Veyhl M, Wagner K, Gambaryan S, Dekel C, Akhoundova A, Korn T, Koepsell H., Biochim Biophys Acta. February 4, 1999; 1417 (1): 131-43.

Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects., Lam JT, Martín MG, Turk E, Hirayama BA, Bosshard NU, Steinmann B, Wright EM., Biochim Biophys Acta. February 24, 1999; 1453 (2): 297-303.

Cloning and functional expression of an SGLT-1-like protein from the Xenopus laevis intestine., Nagata K, Hori N, Sato K, Ohta K, Tanaka H, Hiji Y., Am J Physiol. May 1, 1999; 276 (5): G1251-9.

Passive water and ion transport by cotransporters., Loo DD, Hirayama BA, Meinild AK, Chandy G, Zeuthen T, Wright EM., J Physiol. July 1, 1999; 518 ( Pt 1) 195-202.

Purification and functional reconstitution of a truncated human Na(+)/glucose cotransporter (SGLT1) expressed in E. coli., Panayotova-Heiermann M, Leung DW, Hirayama BA, Wright EM., FEBS Lett. October 15, 1999; 459 (3): 386-90.

Functional expression of tagged human Na+-glucose cotransporter in Xenopus laevis oocytes., Bissonnette P, Noël J, Coady MJ, Lapointe JY., J Physiol. October 15, 1999; 520 Pt 2 359-71.

Effect of benzodiazepines on the epithelial and neuronal high-affinity glutamate transporter EAAC1., Palmada M, Böhmer C, Centelles JJ, Kinne RK., J Neurochem. December 1, 1999; 73 (6): 2389-96.

Molecular water pumps., Zeuthen T., Rev Physiol Biochem Pharmacol. January 1, 2000; 141 97-151.

Voltage and substrate dependence of the inverse transport mode of the rabbit Na(+)/glucose cotransporter (SGLT1)., Sauer GA, Nagel G, Koepsell H, Bamberg E, Hartung K., FEBS Lett. March 3, 2000; 469 (1): 98-100.

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