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Summary Expression Phenotypes Gene Literature (54) GO Terms (8) Nucleotides (396) Proteins (56) Interactants (912) Wiki
XB-GENEPAGE-478451

Papers associated with crx



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Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Gawantka V, Pollet N, Delius H, Vingron M, Pfister R, Nitsch R, Blumenstock C, Niehrs C., Mech Dev. October 1, 1998; 77 (2): 95-141.                                                            


Immediate upstream sequence of arrestin directs rod-specific expression in Xenopus., Mani SS, Besharse JC, Knox BE., J Biol Chem. May 28, 1999; 274 (22): 15590-7.              


Cloning a novel developmental regulating gene, Xotx5: its potential role in anterior formation in Xenopus laevis., Kuroda H, Hayata T, Eisaki A, Asashima M., Dev Growth Differ. April 1, 2000; 42 (2): 87-93.            


Xotx5b, a new member of the Otx gene family, may be involved in anterior and eye development in Xenopus laevis., Vignali R, Colombetti S, Lupo G, Zhang W, Stachel S, Harland RM, Barsacchi G., Mech Dev. August 1, 2000; 96 (1): 3-13.                  


Structural evolution of Otx genes in craniates., Germot A, Lecointre G, Plouhinec JL, Le Mentec C, Girardot F, Mazan S., Mol Biol Evol. September 1, 2001; 18 (9): 1668-78.


Structure and expression of an Otx5-related gene in the dogfish Scyliorhinus canicula: evidence for a conserved role of Otx5 and Crxgenes in the specification of photoreceptors., Sauka-Spengler T, Baratte B, Shi L, Mazan S., Dev Genes Evol. December 1, 2001; 211 (11): 533-44.


Otx5 regulates genes that show circadian expression in the zebrafish pineal complex., Gamse JT, Shen YC, Thisse C, Thisse B, Raymond PA, Halpern ME, Liang JO., Nat Genet. January 1, 2002; 30 (1): 117-21.


Overexpression of the secreted factor Mig30 expressed in the Spemann organizer impairs morphogenetic movements during Xenopus gastrulation., Hayata T, Tanegashima K, Takahashi S, Sogame A, Asashima M., Mech Dev. March 1, 2002; 112 (1-2): 37-51.                


The rod cGMP-phosphodiesterase beta-subunit promoter is a specific target for Sp4 and is not activated by other Sp proteins or CRX., Lerner LE, Gribanova YE, Whitaker L, Knox BE, Farber DB., J Biol Chem. July 19, 2002; 277 (29): 25877-83.


Expression patterns of an Otx2 and an Otx5 orthologue in the urodele Pleurodeles waltl: implications on the evolutionary relationships between the balancers and cement gland in amphibians., Sauka-Spengler T, Germot A, Shi DL, Mazan S., Dev Genes Evol. September 1, 2002; 212 (8): 380-7.


Xenopus laevis red cone opsin and Prph2 promoters allow transgene expression in amphibian cones, or both rods and cones., Moritz OL, Peck A, Tam BM., Gene. October 2, 2002; 298 (2): 173-82.          


A novel function for Hedgehog signalling in retinal pigment epithelium differentiation., Perron M, Boy S, Amato MA, Viczian A, Koebernick K, Pieler T, Harris WA., Development. April 1, 2003; 130 (8): 1565-77.                                  


XOtx5b and XOtx2 regulate photoreceptor and bipolar fates in the Xenopus retina., Viczian AS, Vignali R, Zuber ME, Barsacchi G, Harris WA., Development. April 1, 2003; 130 (7): 1281-94.                    


Isolation and developmental expression of Mitf in Xenopus laevis., Kumasaka M, Sato H, Sato S, Yajima I, Yamamoto H., Dev Dyn. May 1, 2004; 230 (1): 107-13.    


Conserved transcriptional activators of the Xenopus rhodopsin gene., Whitaker SL, Knox BE., J Biol Chem. November 19, 2004; 279 (47): 49010-8.                


Systematic screening for genes specifically expressed in the anterior neuroectoderm during early Xenopus development., Takahashi N, Tochimoto N, Ohmori SY, Mamada H, Itoh M, Inamori M, Shinga J, Osada S, Taira M., Int J Dev Biol. January 1, 2005; 49 (8): 939-51.                                    


Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus., Chen JA, Voigt J, Gilchrist M, Papalopulu N, Amaya E., Mech Dev. March 1, 2005; 122 (3): 307-31.                                                                                                                      


The role of combinational coding by homeodomain and bHLH transcription factors in retinal cell fate specification., Wang JC, Harris WA., Dev Biol. September 1, 2005; 285 (1): 101-15.      


Regulation of melanoblast and retinal pigment epithelium development by Xenopus laevis Mitf., Kumasaka M, Sato S, Yajima I, Goding CR, Yamamoto H., Dev Dyn. November 1, 2005; 234 (3): 523-34.      


Dystroglycan is required for proper retinal layering., Lunardi A, Cremisi F, Dente L., Dev Biol. February 15, 2006; 290 (2): 411-20.            


Genomic analysis of Xenopus organizer function., Hufton AL, Vinayagam A, Suhai S, Baker JC., BMC Dev Biol. June 6, 2006; 6 27.                  


Timing the generation of distinct retinal cells by homeobox proteins., Decembrini S, Andreazzoli M, Vignali R, Barsacchi G, Cremisi F., PLoS Biol. September 1, 2006; 4 (9): e272.                          


The Xenopus ortholog of the nuclear hormone receptor Nr2e3 is primarily expressed in developing photoreceptors., Martinez-De Luna RI, El-Hodiri HM., Int J Dev Biol. January 1, 2007; 51 (3): 235-40.          


Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M, Sauka-Spengler T, Nicolle D, Le-Mentec C, Lallemand Y, Da Silva C, Plouhinec JL, Robert B, Wincker P, Shi DL, Mazan S., PLoS One. April 18, 2007; 2 (4): e374.              


A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina., Onorati M, Cremisi F, Liu Y, He RQ, Barsacchi G, Vignali R., Neural Dev. June 27, 2007; 2 12.            


Nr2e3 and Nrl can reprogram retinal precursors to the rod fate in Xenopus retina., McIlvain VA, Knox BE., Dev Dyn. July 1, 2007; 236 (7): 1970-9.      


Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis., Decembrini S, Andreazzoli M, Barsacchi G, Cremisi F., Int J Dev Biol. January 1, 2008; 52 (8): 1099-103.                


The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus., Fletcher RB, Harland RM., Dev Dyn. May 1, 2008; 237 (5): 1243-54.            


Expression cloning in Xenopus identifies RNA-binding proteins as regulators of embryogenesis and Rbmx as necessary for neural and muscle development., Dichmann DS, Fletcher RB, Harland RM., Dev Dyn. July 1, 2008; 237 (7): 1755-66.                                


CRX controls retinal expression of the X-linked juvenile retinoschisis (RS1) gene., Langmann T, Lai CC, Weigelt K, Tam BM, Warneke-Wittstock R, Moritz OL, Weber BH., Nucleic Acids Res. November 1, 2008; 36 (20): 6523-34.            


Involvement of an inner nuclear membrane protein, Nemp1, in Xenopus neural development through an interaction with the chromatin protein BAF., Mamada H, Takahashi N, Taira M., Dev Biol. March 15, 2009; 327 (2): 497-507.            


Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product., Pan Y, Martinez-De Luna RI, Lou CH, Nekkalapudi S, Kelly LE, Sater AK, El-Hodiri HM., Dev Biol. March 15, 2010; 339 (2): 494-506.              


Xenopus Bsx links daily cell cycle rhythms and pineal photoreceptor fate., D'Autilia S, Broccoli V, Barsacchi G, Andreazzoli M., Proc Natl Acad Sci U S A. April 6, 2010; 107 (14): 6352-7.          


The origin and evolution of ARGFX homeobox loci in mammalian radiation., Li G, Holland PW., BMC Evol Biol. June 17, 2010; 10 182.              


Early onset and differential temporospatial expression of melanopsin isoforms in the developing chicken retina., Verra DM, Contín MA, Hicks D, Guido ME., Invest Ophthalmol Vis Sci. July 29, 2011; 52 (8): 5111-20.


Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the Spemann-Mangold organizer., Sudou N, Yamamoto S, Ogino H, Taira M., Development. May 1, 2012; 139 (9): 1651-61.                  


Cell type-specific translational profiling in the Xenopus laevis retina., Watson FL, Mills EA, Wang X, Guo C, Chen DF, Marsh-Armstrong N., Dev Dyn. December 1, 2012; 241 (12): 1960-72.            


Identification and evolution of molecular domains involved in differentiating the cement gland-promoting activity of Otx proteins in Xenopus laevis., Mancini P, Castelli M, Vignali R., Mech Dev. January 1, 2013; 130 (11-12): 628-39.          


Cooperative activation of Xenopus rhodopsin transcription by paired-like transcription factors., Reks SE, McIlvain V, Zhuo X, Knox BE., BMC Mol Biol. February 6, 2014; 15 4.                  


Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        


Characterization of the Rx1-dependent transcriptome during early retinal development., Giudetti G, Giannaccini M, Biasci D, Mariotti S, Degl'innocenti A, Perrotta M, Barsacchi G, Andreazzoli M., Dev Dyn. October 1, 2014; 243 (10): 1352-61.                                    


Chronic sublethal exposure to silver nanoparticles disrupts thyroid hormone signaling during Xenopus laevis metamorphosis., Carew AC, Hoque ME, Metcalfe CD, Peyrot C, Wilkinson KJ, Helbing CC., Aquat Toxicol. February 1, 2015; 159 99-108.


E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  


Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors., Gazdag E, Jacobi UG, van Kruijsbergen I, Weeks DL, Veenstra GJ., Development. April 15, 2016; 143 (8): 1340-50.                    


Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by vsx gene products., Pan Y, Comiskey DF, Kelly LE, Chandler DS, El-Hodiri HM., Mol Vis. December 14, 2016; 22 1421-1428.        


Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        


A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              


Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling., Jin Y, Weinstein DC., Dev Biol. May 1, 2018; 437 (1): 41-49.          


The C-terminus of the retinal homeobox (rax) gene product modulates transcription in a context-dependent manner., Buescher JL, El-Hodiri HM., Mol Vis. February 23, 2019; 25 165-173.      


Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Paraiso KD, Blitz IL, Zhou JJ, Cho KWY., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.        

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