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Summary Expression Phenotypes Gene Literature (61) GO Terms (9) Nucleotides (179) Proteins (43) Interactants (1207) Wiki
XB--480799

Papers associated with fzd8



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A role for Xenopus Frizzled 8 in dorsal development., Itoh K, Jacob J, Y Sokol S., Mech Dev. June 1, 1998; 74 (1-2): 145-57.  

Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis., Deardorff MA, Tan C, Conrad LJ, Klein PS., Development. July 1, 1998; 125 (14): 2687-700.                  

Characterization of two frizzled8 homologues expressed in the embryonic shield and prechordal plate of zebrafish embryos., Kim SH, Park HC, Yeo SY, Hong SK, Choi JW, Kim CH, Weinstein BM, Huh TL., Mech Dev. November 1, 1998; 78 (1-2): 193-201.

Functional and structural diversity of the human Dickkopf gene family., Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA., Gene. October 1, 1999; 238 (2): 301-13.      

Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development., Baker JC, Beddington RS, Harland RM., Genes Dev. December 1, 1999; 13 (23): 3149-59.              

Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling., Wu W, Glinka A, Delius H, Niehrs C., Curr Biol. December 1, 2000; 10 (24): 1611-4.        

Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway., Wallingford JB, Vogeli KM, Harland RM., Int J Dev Biol. January 1, 2001; 45 (1): 225-7.

Calcium signaling during convergent extension in Xenopus., Wallingford JB, Ewald AJ, Harland RM, Fraser SE., Curr Biol. May 1, 2001; 11 (9): 652-61.              

Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2., Saitoh T, Hirai M, Katoh M., Int J Oncol. May 1, 2001; 18 (5): 991-6.

Vertebrate gastrulation: calcium waves orchestrate cell movements., Tada M, Concha ML., Curr Biol. June 26, 2001; 11 (12): R470-2.

Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development., Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS., Development. October 1, 2001; 128 (19): 3665-74.                

Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis., Lisovsky M, Itoh K, Sokol SY., Curr Biol. January 8, 2002; 12 (1): 53-8.

Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway., Terasaki H, Saitoh T, Shiokawa K, Katoh M., Int J Mol Med. February 1, 2002; 9 (2): 107-12.

Frodo interacts with Dishevelled to transduce Wnt signals., Gloy J, Hikasa H, Sokol SY., Nat Cell Biol. May 1, 2002; 4 (5): 351-7.

The role of Xenopus frizzled-8 in pronephric development., Satow R, Chan TC, Asashima M., Biochem Biophys Res Commun. August 20, 2004; 321 (2): 487-94.          

Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling., Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY., J Biol. January 1, 2005; 4 (1): 3.                  

Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S., Cell. January 28, 2005; 120 (2): 223-35.                      

Comparative genomics on Fzd8 orthologs., Katoh Y, Katoh M., Oncol Rep. May 1, 2005; 13 (5): 993-7.

Vertebrate gastrulation: polarity genes control the matrix., Wallingford JB., Curr Biol. June 7, 2005; 15 (11): R414-6.    

Comparative genomics on Dkk1 orthologs., Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.

Frodo proteins: modulators of Wnt signaling in vertebrate development., Brott BK, Sokol SY., Differentiation. September 1, 2005; 73 (7): 323-9.      

Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase., Itoh K, Lisovsky M, Hikasa H, Sokol SY., Dev Dyn. September 1, 2005; 234 (1): 90-101.              

Novel Daple-like protein positively regulates both the Wnt/beta-catenin pathway and the Wnt/JNK pathway in Xenopus., Kobayashi H, Michiue T, Yukita A, Danno H, Sakurai K, Fukui A, Kikuchi A, Asashima M., Mech Dev. October 1, 2005; 122 (10): 1138-53.                      

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK, Katoh M, Medina A, Steinbeisser H., Cell Commun Signal. October 19, 2005; 3 12.          

Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos., Nagano T, Takehara S, Takahashi M, Aizawa S, Yamamoto A., Development. December 1, 2006; 133 (23): 4643-54.                  

Mutational analysis of Norrin-Frizzled4 recognition., Smallwood PM, Williams J, Xu Q, Leahy DJ, Nathans J., J Biol Chem. February 9, 2007; 282 (6): 4057-68.

Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings., Furushima K, Yamamoto A, Nagano T, Shibata M, Miyachi H, Abe T, Ohshima N, Kiyonari H, Aizawa S., Dev Biol. June 15, 2007; 306 (2): 480-92.  

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling., Luyten A, Mortier E, Van Campenhout C, Taelman V, Degeest G, Wuytens G, Lambaerts K, David G, Bellefroid EJ, Zimmermann P., Mol Biol Cell. April 1, 2008; 19 (4): 1594-604.                  

In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      

Centrosomal localization of Diversin and its relevance to Wnt signaling., Itoh K, Jenny A, Mlodzik M, Sokol SY., J Cell Sci. October 15, 2009; 122 (Pt 20): 3791-8.                

Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G., Proc Natl Acad Sci U S A. November 23, 2010; 107 (47): 20388-93.                          

Expression of Wnt signaling components during Xenopus pronephros development., Zhang B, Tran U, Wessely O., PLoS One. January 1, 2011; 6 (10): e26533.                      

Structural basis of Wnt recognition by Frizzled., Janda CY, Waghray D, Levin AM, Thomas C, Garcia KC., Science. July 6, 2012; 337 (6090): 59-64.

Wnt11b is involved in cilia-mediated symmetry breakage during Xenopus left-right development., Walentek P, Schneider I, Schweickert A, Blum M., PLoS One. January 1, 2013; 8 (9): e73646.              

Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains., Özhan G, Sezgin E, Wehner D, Pfister AS, Kühl SJ, Kagermeier-Schenk B, Kühl M, Schwille P, Weidinger G., Dev Cell. August 26, 2013; 26 (4): 331-45.

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling., Nedelcu D, Liu J, Xu Y, Xu Y, Jao C, Salic A., Nat Chem Biol. September 1, 2013; 9 (9): 557-64.          

Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Vandenberg LN, Blackiston DJ, Rea AC, Dore TM, Levin M., Int J Dev Biol. January 1, 2014; 58 (10-12): 799-809.                

The Wnt/JNK signaling target gene alcam is required for embryonic kidney development., Cizelsky W, Tata A, Kühl M, Kühl SJ., Development. May 1, 2014; 141 (10): 2064-74.          

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling., Fellgett SW, Maguire RJ, Pownall ME., J Cell Sci. April 1, 2015; 128 (7): 1408-21.                        

Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan., Chang TH, Hsieh FL, Zebisch M, Harlos K, Elegheert J, Jones EY., Elife. July 9, 2015; 4                               

Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2., Butler MT, Wallingford JB., Development. October 1, 2015; 142 (19): 3429-39.

GATA2 regulates Wnt signaling to promote primitive red blood cell fate., Mimoto MS, Kwon S, Green YS, Goldman D, Christian JL., Dev Biol. November 1, 2015; 407 (1): 1-11.                          

Mechanotransduction During Vertebrate Neurulation., Sokol SY., Curr Top Dev Biol. January 1, 2016; 117 359-76.

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling., Hamilton PW, Sun Y, Henry JJ., Exp Eye Res. April 1, 2016; 145 206-215.          

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