Results 1 - 50 of 75 results
Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma. , Kuznetsoff JN, Owens DA , Lopez A, Rodriguez DA, Chee NT, Kurtenbach S, Bilbao D, Roberts ER, Volmar CH, Wahlestedt C, Brothers SP, Harbour JW., Mol Cancer Res. February 1, 2021; 19 (2): 215-222.
Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis. , Pentagna N, Pinheiro da Costa T, Soares Dos Santos Cardoso F, Martins de Almeida F, Blanco Martinez AM, Abreu JG , Levin M , Carneiro K., Dev Comp Immunol. January 1, 2021; 114 103840.
Role of epigenetics and miRNAs in orofacial clefts. , Garland MA, Sun B, Zhang S, Reynolds K, Ji Y, Zhou CJ., Birth Defects Res. January 1, 2020; 112 (19): 1635-1659.
HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53. , Capdevielle C, Desplat A, Charpentier J, Sagliocco F, Thiebaud P , Thézé N , Fédou S, Hooks KB, Silvestri R, Guyonnet-Duperat V, Petrel M, Raymond AA, Dupuy JW, Grosset CF, Hagedorn M , Hagedorn M ., Neuro Oncol. January 1, 2020; 22 (4): 550-562.
Involvement of epigenetic modifications in thyroid hormone-dependent formation of adult intestinal stem cells during amphibian metamorphosis. , Fu L, Yin J, Shi YB ., Gen Comp Endocrinol. January 1, 2019; 271 91-96.
FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae). , Naumann B, Schmidt J, Olsson L ., Dev Dyn. January 1, 2019; 248 (5): 323-336.
Autophagy Induction by HDAC Inhibitors Is Unlikely to be the Mechanism of Efficacy in Prevention of Retinal Degeneration Caused by P23H Rhodopsin. , Wen RH, Loewen AD, Vent-Schmidt RYJ, Moritz OL ., Adv Exp Med Biol. January 1, 2019; 1185 401-405.
A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis. , Christov CP, Dingwell KS, Skehel M, Wilkes HS, Sale JE, Smith JC , Krude T., Cell Rep. January 1, 2018; 22 (9): 2265-2278.
Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest. , Rao A, LaBonne C ., Development. January 1, 2018; 145 (15):
Xenopus SOX5 enhances myogenic transcription indirectly through transrepression. , Della Gaspera B , Chesneau A, Weill L, Charbonnier F, Chanoine C ., Dev Biol. January 1, 2018; 442 (2): 262-275.
Opposing effects of valproic acid treatment mediated by histone deacetylase inhibitor activity in four transgenic X. laevis models of retinitis pigmentosa. , Vent-Schmidt RY, Wen RH, Zong Z, Chiu CN, May CG, Tam BM, Moritz OL ., J Neurosci. August 1, 2017;
Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa. , Vent-Schmidt RYJ, Wen RH, Zong Z, Chiu CN, Tam BM, May CG, Moritz OL ., J Neurosci. January 1, 2017; 37 (4): 1039-1054.
Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells. , Zhang Z , Lei A, Xu L, Chen L, Chen Y , Chen Y , Zhang X, Gao Y, Yang X, Zhang M, Cao Y , Cao Y ., J Biol Chem. January 1, 2017; 292 (31): 12842-12859.
A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT. , Gao L, Zhu X, Chen G, Ma X , Zhang Y , Zhang Y , Khand AA, Shi H , Gu F, Lin H, Chen Y , Zhang H , He L, Tao Q , Tao Q ., Development. February 1, 2016; 143 (3): 492-503.
HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum. , Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W., Front Cell Neurosci. January 1, 2016; 10 221.
The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells. , El-Hage P, Petitalot A, Monsoro-Burq AH , Maczkowiak F, Driouch K, Formstecher E, Camonis J, Sabbah M, Bièche I, Lidereau R, Lallemand F., Mol Cancer Res. May 1, 2015; 13 (5): 902-12.
HDAC1 Regulates the Proliferation of Radial Glial Cells in the Developing Xenopus Tectum. , Tao Y, Ruan H, Guo X, Li L, Shen W., PLoS One. January 1, 2015; 10 (3): e0120118.
Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum. , Guo X, Ruan H, Li X, Qin L, Tao Y, Qi X, Gao J, Gan L, Duan S, Shen W., Front Cell Neurosci. January 1, 2015; 9 510.
Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range. , Chernet BT , Levin M ., Oncotarget. May 30, 2014; 5 (10): 3287-306.
Epigenetic regulation of thyroid hormone-induced adult intestinal stem cell development during anuran metamorphosis. , Sun G , Fu L, Shi YB ., Cell Biosci. January 1, 2014; 4 73.
Apelin- APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development. , Kang Y, Kim J , Anderson JP, Wu J , Gleim SR, Kundu RK, McLean DL, Kim JD , Park H, Jin SW, Hwa J, Quertermous T, Chun HJ., Circ Res. June 21, 2013; 113 (1): 22-31.
A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development. , Paranjpe SS, Jacobi UG, van Heeringen SJ, Veenstra GJ ., BMC Genomics. May 28, 2013; 14 762.
Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model. , Chernet BT , Levin M ., Dis Model Mech. May 1, 2013; 6 (3): 595-607.
Histone deacetylase induces accelerated maturation in Xenopus laevis oocytes. , Iwashita J, Kodama A, Konno Y, Abe T, Murata J., Dev Growth Differ. April 1, 2013; 55 (3): 319-29.
Regulation of primitive hematopoiesis by class I histone deacetylases. , Shah RR, Koniski A, Shinde M, Blythe SA , Fass DM, Haggarty SJ, Palis J, Klein PS ., Dev Dyn. February 1, 2013; 242 (2): 108-21.
Unliganded thyroid hormone receptor regulates metamorphic timing via the recruitment of histone deacetylase complexes. , Shi YB ., Curr Top Dev Biol. January 1, 2013; 105 275-97.
SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest. , Lee PC, Taylor-Jaffe KM, Nordin KM, Prasad MS , Lander RM, LaBonne C ., J Cell Biol. September 3, 2012; 198 (5): 799-813.
Histone deacetylases are required for amphibian tail and limb regeneration but not development. , Taylor AJ, Beck CW ., Mech Dev. September 1, 2012; 129 (9-12): 208-18.
The LIM adaptor protein LMO4 is an essential regulator of neural crest development. , Ochoa SD, Salvador S, LaBonne C ., Dev Biol. January 15, 2012; 361 (2): 313-25.
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. , Babu E, Ramachandran S, CoothanKandaswamy V, Elangovan S, Prasad PD, Ganapathy V, Thangaraju M., Oncogene. September 22, 2011; 30 (38): 4026-37.
Histone deacetylase activity is necessary for left- right patterning during vertebrate development. , Carneiro K, Donnet C, Rejtar T, Karger BL, Barisone GA, Díaz E, Kortagere S, Lemire JM , Levin M ., BMC Dev Biol. May 20, 2011; 11 29.
Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early Xenopus embryos. , Bogdanović O, Veenstra GJ ., BMC Res Notes. May 6, 2011; 4 300.
HDAC activity is required during Xenopus tail regeneration. , Tseng AS , Carneiro K, Lemire JM , Levin M ., PLoS One. January 1, 2011; 6 (10): e26382.
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. , Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN , Reis SA, Klein PS , Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ., ACS Med Chem Lett. October 8, 2010; 2 (1): 39-42.
Molecular and genetic studies suggest that thyroid hormone receptor is both necessary and sufficient to mediate the developmental effects of thyroid hormone. , Das B, Matsuda H, Fujimoto K , Sun G , Matsuura K, Shi YB , Shi YB ., Gen Comp Endocrinol. September 1, 2010; 168 (2): 174-80.
A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation. , Hageman J, Rujano MA, van Waarde MA, Kakkar V, Dirks RP , Govorukhina N, Oosterveld-Hut HM, Lubsen NH, Kampinga HH., Mol Cell. February 12, 2010; 37 (3): 355-69.
Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 ( HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate. , Thangaraju M, Karunakaran SK, Itagaki S, Gopal E, Elangovan S, Prasad PD, Ganapathy V., Cancer. October 15, 2009; 115 (20): 4655-66.
The Xenopus Bowline/Ripply family proteins negatively regulate the transcriptional activity of T-box transcription factors. , Hitachi K , Danno H, Tazumi S, Aihara Y, Uchiyama H, Okabayashi K , Kondow A , Asashima M ., Int J Dev Biol. January 1, 2009; 53 (4): 631-9.
Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation. , Cao Y , Siegel D , Oswald F, Knöchel W ., J Biol Chem. December 5, 2008; 283 (49): 34168-77.
Role for histone deacetylase 1 in human tumor cell proliferation. , Senese S, Zaragoza K, Minardi S, Muradore I, Ronzoni S, Passafaro A, Bernard L, Draetta GF, Alcalay M, Seiser C, Chiocca S., Mol Cell Biol. July 1, 2007; 27 (13): 4784-95.
A role of unliganded thyroid hormone receptor in postembryonic development in Xenopus laevis. , Sato Y, Buchholz DR , Paul BD , Shi YB , Shi YB ., Mech Dev. July 1, 2007; 124 (6): 476-88.
Characterization of histone lysine-specific demethylase in relation to thyroid hormone-regulated anuran metamorphosis. , Chen W, Obara M, Ishida Y, Suzuki K , Yoshizato K ., Dev Growth Differ. May 1, 2007; 49 (4): 325-34.
FoxN3 is required for craniofacial and eye development of Xenopus laevis. , Schuff M, Rössner A, Wacker SA, Donow C, Gessert S , Knöchel W ., Dev Dyn. January 1, 2007; 236 (1): 226-39.
Inhibition of histone deacetylase as a new mechanism of teratogenesis. , Menegola E, Di Renzo F, Broccia ML, Giavini E., Birth Defects Res C Embryo Today. December 1, 2006; 78 (4): 345-53.
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/ SMRT corepressors on chromatin. , Vermeulen M, Walter W, Le Guezennec X, Kim J , Edayathumangalam RS, Lasonder E, Luger K, Roeder RG, Logie C, Berger SL, Stunnenberg HG., Mol Cell Biol. July 1, 2006; 26 (14): 5226-36.
Histone deacetylase activity is necessary for chromosome condensation during meiotic maturation in Xenopus laevis. , Magnaghi-Jaulin L, Jaulin C., Chromosome Res. January 1, 2006; 14 (3): 319-32.
Molecular and developmental analyses of thyroid hormone receptor function in Xenopus laevis, the African clawed frog. , Buchholz DR , Paul BD , Fu L, Shi YB , Shi YB ., Gen Comp Endocrinol. January 1, 2006; 145 (1): 1-19.
Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo. , Gurvich N, Berman MG, Wittner BS, Gentleman RC, Klein PS , Green JB ., FASEB J. July 1, 2005; 19 (9): 1166-8.
Regulation of tissue-specific and extracellular matrix-related genes by a class I histone deacetylase. , Whetstine JR, Ceron J, Ladd B, Dufourcq P, Reinke V, Shi Y ., Mol Cell. May 13, 2005; 18 (4): 483-90.
Nuclear import and activity of histone deacetylase in Xenopus oocytes is regulated by phosphorylation. , Smillie DA, Llinas AJ, Ryan JT, Kemp GD, Sommerville J., J Cell Sci. April 1, 2004; 117 (Pt 9): 1857-66.