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Summary Expression Phenotypes Gene Literature (33) GO Terms (1) Nucleotides (125) Proteins (50) Interactants (337) Wiki
XB-GENEPAGE-481425

Papers associated with hand2



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A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice., Charng MJ, Frenkel PA, Lin Q, Yamada M, Schwartz RJ, Olson EN, Overbeek P, Schneider MD, Yumada M., Dev Biol. July 1, 1998; 199 (1): 72-9.

Seeking a regulatory roadmap for heart morphogenesis., Harvey RP., Semin Cell Dev Biol. February 1, 1999; 10 (1): 99-107.

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand., Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE., Dev Biol. January 15, 2000; 217 (2): 266-77.  

Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development., Angelo S, Lohr J, Lee KH, Ticho BS, Breitbart RE, Hill S, Yost HJ, Srivastava D., Mech Dev. July 1, 2000; 95 (1-2): 231-7.                            

Xenopus Hand2 expression marks anterior vascular progenitors but not the developing heart., Smith SJ, Kotecha S, Towers N, Mohun TJ., Dev Dyn. December 1, 2000; 219 (4): 575-81.      

Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription., Poizat C, Sartorelli V, Chung G, Kloner RA, Kedes L., Mol Cell Biol. December 1, 2000; 20 (23): 8643-54.

The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation., Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D., Dev Biol. November 15, 2001; 239 (2): 190-203.

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling., te Welscher P, Fernandez-Teran M, Ros MA, Zeller R., Genes Dev. February 15, 2002; 16 (4): 421-6.

The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene., Thattaliyath BD, Firulli BA, Firulli AB., J Mol Cell Cardiol. October 1, 2002; 34 (10): 1335-44.

Characterization of Xenopus Phox2a and Phox2b defines expression domains within the embryonic nervous system and early heart field., Talikka M, Stefani G, Brivanlou AH, Zimmerman K., Gene Expr Patterns. September 1, 2004; 4 (5): 601-7.      

Modulating the activity of neural crest regulatory factors., Taylor KM, LaBonne C., Curr Opin Genet Dev. August 1, 2007; 17 (4): 326-31.  

Constitutive over-expression of VEGF results in reduced expression of Hand-1 during cardiac development in Xenopus., Nagao K, Taniyama Y, Koibuchi N, Morishita R., Biochem Biophys Res Commun. August 3, 2007; 359 (3): 431-7.        

Correlation between Shh expression and DNA methylation status of the limb-specific Shh enhancer region during limb regeneration in amphibians., Yakushiji N, Suzuki M, Satoh A, Sagai T, Shiroishi T, Kobayashi H, Sasaki H, Ide H, Tamura K, Tamura K., Dev Biol. December 1, 2007; 312 (1): 171-82.  

The mych gene is required for neural crest survival during zebrafish development., Hong SK, Tsang M, Dawid IB., PLoS One. April 9, 2008; 3 (4): e2029.                

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus., Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R., J Biol Chem. April 25, 2008; 283 (17): 11841-9.                        

Xenopus zinc finger transcription factor IA1 (Insm1) expression marks anteroventral noradrenergic neuron progenitors in Xenopus embryos., Parlier D, Ariza A, Christulia F, Genco F, Vanhomwegen J, Kricha S, Souopgui J, Bellefroid EJ., Dev Dyn. August 1, 2008; 237 (8): 2147-57.          

Effects of activation of hedgehog signaling on patterning, growth, and differentiation in Xenopus froglet limb regeneration., Yakushiji N, Suzuki M, Satoh A, Ide H, Tamura K, Tamura K., Dev Dyn. August 1, 2009; 238 (8): 1887-96.          

Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis., Gessert S, Kühl M., Dev Biol. October 15, 2009; 334 (2): 395-408.          

Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus., Reisoli E, De Lucchini S, Nardi I, Ori M., Development. September 1, 2010; 137 (17): 2927-37.                            

Transcriptomic analysis of avian digits reveals conserved and derived digit identities in birds., Wang Z, Young RL, Xue H, Wagner GP., Nature. September 4, 2011; 477 (7366): 583-6.

Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos., Herrmann F, Bundschu K, Kühl SJ, Kühl M., Dev Dyn. December 1, 2011; 240 (12): 2634-45.  

Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton., Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF., Development. December 1, 2011; 138 (23): 5135-46.

Imparting regenerative capacity to limbs by progenitor cell transplantation., Lin G, Chen Y, Chen Y, Slack JM., Dev Cell. January 14, 2013; 24 (1): 41-51.                          

Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina., Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M., PLoS One. March 18, 2014; 9 (3): e92113.                        

A gene expression map of the larval Xenopus laevis head reveals developmental changes underlying the evolution of new skeletal elements., Square T, Jandzik D, Cattell M, Coe A, Doherty J, Medeiros DM., Dev Biol. January 15, 2015; 397 (2): 293-304.                                            

Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes., Sun YB, Xiong ZJ, Xiang XY, Liu SP, Zhou WW, Tu XL, Zhong L, Wang L, Wu DD, Zhang BL, Zhu CL, Yang MM, Chen HM, Li F, Zhou L, Feng SH, Huang C, Zhang GJ, Irwin D, Hillis DM, Murphy RW, Yang HM, Che J, Wang J, Zhang YP., Proc Natl Acad Sci U S A. March 17, 2015; 112 (11): E1257-62.      

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ, Philpott A., Dis Model Mech. May 1, 2015; 8 (5): 429-41.                

CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart., Blech-Hermoni Y, Sullivan CB, Jenkins MW, Wessely O, Ladd AN., Dev Dyn. August 1, 2016; 245 (8): 854-73.                      

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.                            

Noggin is required for first pharyngeal arch differentiation in the frog Xenopus tropicalis., Young JJ, Kjolby RAS, Wu G, Wong D, Hsu SW, Harland RM., Dev Biol. June 15, 2017; 426 (2): 245-254.                

Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.                

Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish., Bisgrove BW, Su YC, Yost HJ., Elife. November 15, 2017; 6                 

Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):                         

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