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Summary Expression Phenotypes Gene Literature (197) GO Terms (5) Nucleotides (130) Proteins (44) Interactants (1264) Wiki
XB-GENEPAGE-481643

Papers associated with dkk1



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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction., Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C., Nature. January 22, 1998; 391 (6665): 357-62.

Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Gawantka V, Pollet N, Delius H, Vingron M, Pfister R, Nitsch R, Blumenstock C, Niehrs C., Mech Dev. October 1, 1998; 77 (2): 95-141.                                                            

Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis., Osada SI, Wright CV., Development. June 1, 1999; 126 (14): 3229-40.                

Keeping a close eye on Wnt-1/wg signaling in Xenopus., Gradl D, Kühl M, Wedlich D., Mech Dev. August 1, 1999; 86 (1-2): 3-15.    

Characterization of a novel member of the FGF family, XFGF-20, in Xenopus laevis., Koga C, Adati N, Nakata K, Mikoshiba K, Furuhata Y, Sato S, Tei H, Sakaki Y, Kurokawa T, Shiokawa K, Yokoyama KK., Biochem Biophys Res Commun. August 11, 1999; 261 (3): 756-65.                  

Dickkopf genes are co-ordinately expressed in mesodermal lineages., Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C., Mech Dev. September 1, 1999; 87 (1-2): 45-56.      

Functional and structural diversity of the human Dickkopf gene family., Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA., Gene. October 1, 1999; 238 (2): 301-13.      

Expression pattern of Dkk-1 during mouse limb development., Grotewold L, Theil T, Rüther U., Mech Dev. December 1, 1999; 89 (1-2): 151-3.

The genomic structure, chromosome location, and analysis of the human DKK1 head inducer gene as a candidate for holoprosencephaly., Roessler E, Du Y, Glinka A, Dutra A, Niehrs C, Muenke M., Cytogenet Cell Genet. January 1, 2000; 89 (3-4): 220-4.

Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation., Hashimoto H, Itoh M, Yamanaka Y, Yamashita S, Shimizu T, Solnica-Krezel L, Hibi M, Hirano T., Dev Biol. January 1, 2000; 217 (1): 138-52.  

Xenopus crescent encoding a Frizzled-like domain is expressed in the Spemann organizer and pronephros., Shibata M, Ono H, Hikasa H, Shinga J, Taira M., Mech Dev. September 1, 2000; 96 (2): 243-6.  

Expression of the zinc finger gene fez-like in zebrafish forebrain., Hashimoto H, Yabe T, Hirata T, Shimizu T, Bae Y, Yamanaka Y, Hirano T, Hibi M., Mech Dev. October 1, 2000; 97 (1-2): 191-5.

Zebrafish Dkk1, induced by the pre-MBT Wnt signaling, is secreted from the prechordal plate and patterns the anterior neural plate., Shinya M, Eschbach C, Clark M, Lehrach H, Furutani-Seiki M., Mech Dev. November 1, 2000; 98 (1-2): 3-17.

The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning., Kazanskaya O, Glinka A, Niehrs C., Development. November 1, 2000; 127 (22): 4981-92.              

Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling., Wu W, Glinka A, Delius H, Niehrs C., Curr Biol. December 1, 2000; 10 (24): 1611-4.        

Dickkopf1 and the Spemann-Mangold head organizer., Niehrs C, Kazanskaya O, Wu W, Glinka A., Int J Dev Biol. January 1, 2001; 45 (1): 237-40.    

A study of Xlim1 function in the Spemann-Mangold organizer., Kodjabachian L, Karavanov AA, Hikasa H, Hukriede NA, Aoki T, Taira M, Dawid IB., Int J Dev Biol. January 1, 2001; 45 (1): 209-18.            

The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. ., Faucourt M, Houliston E, Besnardeau L, Kimelman D, Lepage T., Dev Biol. January 15, 2001; 229 (2): 287-306.                

Inhibition of Wnt activity induces heart formation from posterior mesoderm., Marvin MJ, Di Rocco G, Gardiner A, Bush SM, Lassar AB., Genes Dev. February 1, 2001; 15 (3): 316-27.  

Wnt antagonism initiates cardiogenesis in Xenopus laevis., Schneider VA, Mercola M., Genes Dev. February 1, 2001; 15 (3): 304-15.        

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins., Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C., Nature. May 17, 2001; 411 (6835): 321-5.

Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus., Wessely O, Agius E, Oelgeschläger M, Pera EM, De Robertis EM., Dev Biol. June 1, 2001; 234 (1): 161-73.              

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6., Semënov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X., Curr Biol. June 26, 2001; 11 (12): 951-61.

Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse., Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, Dorward DW, Glinka A, Grinberg A, Huang SP, Niehrs C, Izpisúa Belmonte JC, Westphal H., Dev Cell. September 1, 2001; 1 (3): 423-34.

Siamois functions in the early blastula to induce Spemann's organiser., Kodjabachian L, Lemaire P., Mech Dev. October 1, 2001; 108 (1-2): 71-9.          

A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus., Kiecker C, Niehrs C., Development. November 1, 2001; 128 (21): 4189-201.              

Systematic screening and expression analysis of the head organizer genes in Xenopus embryos., Shibata M, Itoh M, Ohmori SY, Shinga J, Taira M., Dev Biol. November 15, 2001; 239 (2): 241-56.                  

Bmp, Fgf and Wnt signalling in programmed cell death and chondrogenesis during vertebrate limb development: the role of Dickkopf-1., Grotewold L, Rüther U., Int J Dev Biol. January 1, 2002; 46 (7): 943-7.

The promise and perils of Wnt signaling through beta-catenin., Moon RT, Bowerman B, Boutros M, Perrimon N., Science. May 31, 2002; 296 (5573): 1644-6.

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins., Brott BK, Sokol SY., Mol Cell Biol. September 1, 2002; 22 (17): 6100-10.

Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning., Davidson G, Mao B, del Barco Barrantes I, Niehrs C., Development. December 1, 2002; 129 (24): 5587-96.        

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling., Mao B, Niehrs C., Gene. January 2, 2003; 302 (1-2): 179-83.        

Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling., Yabe T, Shimizu T, Muraoka O, Bae YK, Hirata T, Nojima H, Kawakami A, Hirano T, Hibi M., Development. June 1, 2003; 130 (12): 2705-16.

Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants., Latinkić BV, Kotecha S, Mohun TJ., Development. August 1, 2003; 130 (16): 3865-76.              

Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions., Hiratani I, Yamamoto N, Mochizuki T, Ohmori SY, Taira M., Development. September 1, 2003; 130 (17): 4161-75.                    

Dkk1 and noggin cooperate in mammalian head induction., del Barco Barrantes I, Davidson G, Gröne HJ, Westphal H, Niehrs C., Genes Dev. September 15, 2003; 17 (18): 2239-44.

PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development., Yang J, Wu J, Tan C, Klein PS., Development. December 1, 2003; 130 (23): 5569-78.            

Expression analysis of chick Wnt and frizzled genes and selected inhibitors in early chick patterning., Chapman SC, Brown R, Lees L, Schoenwolf GC, Lumsden A., Dev Dyn. March 1, 2004; 229 (3): 668-76.

A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways., Zuzarte-Luís V, Montero JA, Rodriguez-León J, Merino R, Rodríguez-Rey JC, Hurlé JM., Dev Biol. August 1, 2004; 272 (1): 39-52.

New roles for FoxH1 in patterning the early embryo., Kofron M, Puck H, Standley H, Wylie C, Old R, Whitman M, Heasman J., Development. October 1, 2004; 131 (20): 5065-78.              

Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition., Delaune E, Lemaire P, Kodjabachian L., Development. January 1, 2005; 132 (2): 299-310.                    

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development., Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE., EMBO J. January 12, 2005; 24 (1): 73-84.

Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S., Cell. January 28, 2005; 120 (2): 223-35.                      

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

Comparative genomics on Dkk1 orthologs., Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.

The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system., Huang X, Hong CS, O'Donnell M, Saint-Jeannet JP., Proc Natl Acad Sci U S A. August 9, 2005; 102 (32): 11349-54.                        

An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation., Matsuo-Takasaki M, Matsumura M, Sasai Y., Development. September 1, 2005; 132 (17): 3885-94.                      

Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer., Yamaguti M, Cho KW, Hashimoto C., Dev Dyn. September 1, 2005; 234 (1): 102-13.          

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK, Katoh M, Medina A, Steinbeisser H., Cell Commun Signal. October 19, 2005; 3 12.          

Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo., Carron C, Bourdelas A, Li HY, Boucaut JC, Shi DL., Mech Dev. November 1, 2005; 122 (11): 1234-47.                

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