mdm2 Literature

XB-GENEPAGE-482710

Papers associated with mdm2

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	The Multifaceted Roles of USP15 in Signal Transduction., Das T, Song EJ, Kim EE., Int J Mol Sci. April 29, 2021; 22 (9):
	Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant., Magnussen HM, Huang DT., J Mol Biol. March 5, 2021; 433 (5): 166807.
	Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Feng C, Zhang HL, Zeng A, Bai M, Wang XJ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.
	Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model., Tran DP, Kitao A., J Phys Chem B. March 21, 2019; 123 (11): 2469-2478.
	Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.
	Photoactivation of MDM2 Inhibitors: Controlling Protein-Protein Interaction with Light., Hansen MJ, Feringa FM, Kobauri P, Szymanski W, Medema RH, Feringa BL., J Am Chem Soc. October 17, 2018; 140 (41): 13136-13141.
	Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.
	Comparative studies of apoptosis in Xenopus laevis and mouse thymoma cell lines., Johnson RO, Tittle TV, Sefchick MP, Zettergren LD, Ruben LN, Clothier RH, Balls M., Altern Lab Anim. July 1, 2013; 41 (3): 211-8.
	MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis., Bonev B, Pisco A, Papalopulu N., Dev Cell. January 18, 2011; 20 (1): 19-32.
	Aromatic-aromatic interactions in the formation of the MDM2-p53 complex., Espinoza-Fonseca LM, García-Machorro J., Biochem Biophys Res Commun. June 13, 2008; 370 (4): 547-51.
	Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft., Showalter SA, Bruschweiler-Li L, Johnson E, Zhang F, Brüschweiler R., J Am Chem Soc. May 21, 2008; 130 (20): 6472-8.
	Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer., Villiard E, Brinkmann H, Moiseeva O, Mallette FA, Ferbeyre G, Roy S., BMC Evol Biol. September 28, 2007; 7 180.
	Occurrence of pre-MBT synthesis of caspase-8 mRNA and activation of caspase-8 prior to execution of SAMDC (S-adenosylmethionine decarboxylase)-induced, but not p53-induced, apoptosis in Xenopus late blastulae., Shiokawa K, Takayama E, Higo T, Kuroyanagi S, Kaito C, Hara H, Kajitani M, Sekimizu K, Tadakuma T, Miura K, Igarashi K, Yaoita Y., Biochem Biophys Res Commun. October 21, 2005; 336 (2): 682-91.
	Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding., Uhrinova S, Uhrin D, Powers H, Watt K, Zheleva D, Fischer P, McInnes C, Barlow PN., J Mol Biol. July 15, 2005; 350 (3): 587-98.
	NMR structure of a complex between MDM2 and a small molecule inhibitor., Fry DC, Emerson SD, Palme S, Vu BT, Liu CM, Podlaski F., J Biomol NMR. October 1, 2004; 30 (2): 163-73.
	Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis., Gu L, Zheng H, Murray SA, Ying H, Jim Xiao ZX., Biochem Biophys Res Commun. March 7, 2003; 302 (2): 384-91.
	Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis., Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.
	Monoclonal antibodies raised against Xenopus p53 interact with human p73., Le Bras M, Delattre V, Bensaad K, Blandino G, Soussi T., Oncogene. February 14, 2002; 21 (8): 1304-8.
	QSAR: hydropathic analysis of inhibitors of the p53-mdm2 interaction., Galatin PS, Abraham DJ., Proteins. November 15, 2001; 45 (3): 169-75.
	Critical residues of epitopes recognized by several anti-p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein., Portefaix JM, Thebault S, Bourgain-Guglielmetti F, Del Rio M, Granier C, Mani JC, Navarro-Teulon I, Nicolas M, Soussi T, Pau B., J Immunol Methods. October 20, 2000; 244 (1-2): 17-28.
	The Mdm2 gene of zebrafish (Danio rerio): preferential expression during development of neural and muscular tissues, and absence of tumor formation after overexpression of its cDNA during early embryogenesis., Thisse C, Neel H, Thisse B, Daujat S, Piette J., Differentiation. October 1, 2000; 66 (2-3): 61-70.
	A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking., Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM., EMBO J. March 15, 1999; 18 (6): 1660-72.
	Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein., Bessard AC, Garay E, Lacronique V, Legros Y, Demarquay C, Houque A, Portefaix JM, Granier C, Soussi T., Oncogene. February 19, 1998; 16 (7): 883-90.
	Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis., Marechal V, Elenbaas B, Taneyhill L, Piette J, Mechali M, Nicolas JC, Levine AJ, Moreau J., Oncogene. March 27, 1997; 14 (12): 1427-33.

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