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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki
XB--482929

Papers associated with smad2 (and morpholino)



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The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling., Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW., Genes Dev. April 1, 2002; 16 (7): 820-35.    

The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein., Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R., Int J Dev Biol. February 1, 2003; 47 (1): 15-29.                  

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads., Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S., Cell. May 2, 2003; 113 (3): 301-14.  

Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation., Daniels M, Shimizu K, Zorn AM, Ohnuma S., Development. November 1, 2004; 131 (22): 5613-26.                                

Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation., Daniels M, Shimizu K, Zorn AM, Ohnuma S., Development. November 1, 2004; 131 (22): 5613-26.                                

The ARID domain protein dril1 is necessary for TGF(beta) signaling in Xenopus embryos., Callery EM, Smith JC, Thomsen GH., Dev Biol. February 15, 2005; 278 (2): 542-59.                              

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase., Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M, Piccolo S., Cell. April 8, 2005; 121 (1): 87-99.                                  

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo., Collart C, Verschueren K, Rana A, Smith JC, Huylebroeck D., Development. October 1, 2005; 132 (20): 4575-86.        

Vg 1 is an essential signaling molecule in Xenopus development., Birsoy B, Kofron M, Schaible K, Wylie C, Heasman J., Development. January 1, 2006; 133 (1): 15-20.    

A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos., Dorey K, Hill CS., Dev Biol. April 15, 2006; 292 (2): 303-16.  

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development., Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS., Development. December 1, 2006; 133 (24): 4827-38.                    

Xenopus Dab2 is required for embryonic angiogenesis., Cheong SM, Choi SC, Han JK., BMC Dev Biol. December 19, 2006; 6 63.                  

Negative regulation of Activin/Nodal signaling by SRF during Xenopus gastrulation., Yun CH, Choi SC, Park E, Kim SJ, Chung AS, Lee HK, Lee HK, Lee HJ, Lee HJ, Han JK., Development. February 1, 2007; 134 (4): 769-77.              

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

XSUMO-1 is required for normal mesoderm induction and axis elongation during early Xenopus development., Yukita A, Michiue T, Danno H, Asashima M., Dev Dyn. October 1, 2007; 236 (10): 2757-66.    

Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., Morris SA, Almeida AD, Tanaka H, Ohta K, Ohnuma S., PLoS One. October 10, 2007; 2 (10): e1004.                    

Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S, Niehrs C., Differentiation. December 1, 2007; 75 (10): 957-67.            

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1., Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M., Development. May 1, 2008; 135 (10): 1813-22.                    

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling., Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M., Development. September 1, 2008; 135 (17): 2927-37.  

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination., Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello G, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N, Argenton F, Newfeld SJ, Piccolo S., Cell. January 9, 2009; 136 (1): 123-35.  

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos., Cheong SM, Kim H, Han JK., J Biol Chem. June 19, 2009; 284 (25): 17052-60.                        

The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo., Ho DM, Yeo CY, Whitman M., Mech Dev. January 1, 2010; 127 (9-12): 485-95.                  

The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo., Ho DM, Yeo CY, Whitman M., Mech Dev. January 1, 2010; 127 (9-12): 485-95.                  

SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos., Wu MY, Ramel MC, Howell M, Hill CS., PLoS Biol. February 15, 2011; 9 (2): e1000593.                              

A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            

HEB and E2A function as SMAD/FOXH1 cofactors., Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC., Genes Dev. August 1, 2011; 25 (15): 1654-61.            

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis., Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M., Genes Dev. December 1, 2012; 26 (23): 2567-79.      

Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus., Lim CY, Reversade B, Knowles BB, Solter D., Development. February 1, 2013; 140 (4): 853-60.                                              

Lin28 proteins are required for germ layer specification in Xenopus., Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV., Development. March 1, 2013; 140 (5): 976-86.                      

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1., Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO., Genes Dev. March 1, 2013; 27 (5): 491-503.                        

RAB8B is required for activity and caveolar endocytosis of LRP6., Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M., Cell Rep. September 26, 2013; 4 (6): 1224-34.                    

In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency., Gentsch GE, Owens ND, Martin SR, Piccinelli P, Faial T, Trotter MW, Gilchrist MJ, Smith JC., Cell Rep. September 26, 2013; 4 (6): 1185-96.                              

Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling., Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E., Development. October 1, 2013; 140 (20): 4177-81.              

Activin ligands are required for the re-activation of Smad2 signalling after neurulation and vascular development in Xenopus tropicalis., Nagamori Y, Roberts S, Maciej M, Dorey K., Int J Dev Biol. January 1, 2014; 58 (10-12): 783-91.            

Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos., Kirmizitas A, Gillis WQ, Zhu H, Thomsen GH., Dev Biol. August 15, 2014; 392 (2): 358-67.                                

Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression., Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce AE, Wardle FC., BMC Biol. October 3, 2014; 12 81.            

Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm., Nordin K, LaBonne C., Dev Cell. November 10, 2014; 31 (3): 374-382.                              

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

TGF-β Signaling Regulates the Differentiation of Motile Cilia., Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y., Cell Rep. May 19, 2015; 11 (7): 1000-7.                

TGF-β Signaling Regulates the Differentiation of Motile Cilia., Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y., Cell Rep. May 19, 2015; 11 (7): 1000-7.                

Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo., Nishitani E, Li C, Lee J, Hotta H, Katayama Y, Yamaguchi M, Kinoshita T., Dev Growth Differ. December 1, 2015; 57 (9): 591-600.              

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