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Summary Expression Phenotypes Gene Literature (640) GO Terms (12) Nucleotides (235) Proteins (78) Interactants (1937) Wiki
XB--483057

Papers associated with bmp4 (and furin)



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R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  

SMOC-1 interacts with both BMP and glypican to regulate BMP signaling in C. elegans., DeGroot MS, Williams B, Chang TY, Maas Gamboa ML, Larus IM, Hong G, Fromme JC, Liu J., PLoS Biol. August 1, 2023; 21 (8): e3002272.                        

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                

Pinhead antagonizes Admp to promote notochord formation., Itoh K, Ossipova O, Sokol SY., iScience. May 7, 2021; 24 (6): 102520.                            

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

Site-specific cleavage of BMP4 by furin, PC6, and PC7., Nelsen SM, Christian JL., J Biol Chem. October 2, 2009; 284 (40): 27157-66.

Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain., Sopory S, Nelsen SM, Degnin C, Wong C, Christian JL., J Biol Chem. November 10, 2006; 281 (45): 34021-31.

CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces., Thomas JT, Prakash D, Weih K, Moos M., J Biol Chem. September 8, 2006; 281 (36): 26725-33.              

Emilin1 links TGF-beta maturation to blood pressure homeostasis., Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S, Cifelli G, Ferrari A, Maffei A, Fabbro C, Braghetta P, Marino G, Selvetella G, Aretini A, Colonnese C, Bettarini U, Russo G, Soligo S, Adorno M, Bonaldo P, Volpin D, Piccolo S, Lembo G, Bressan GM., Cell. March 10, 2006; 124 (5): 929-42.    

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development., Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J., Development. February 1, 2005; 132 (3): 591-602.                      

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor., Cui Y, Hackenmiller R, Berg L, Jean F, Nakayama T, Thomas G, Christian JL., Genes Dev. November 1, 2001; 15 (21): 2797-802.

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development., Cui Y, Jean F, Thomas G, Christian JL., EMBO J. August 17, 1998; 17 (16): 4735-43.

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