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Summary Expression Phenotypes Gene Literature (500) GO Terms (3) Nucleotides (62) Proteins (38) Interactants (1603) Wiki
XB--483208

Papers associated with nodal (and morpholino)



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referenced by:

Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo., Erter CE, Wilm TP, Basler N, Wright CV, Solnica-Krezel L., Development. September 1, 2001; 128 (18): 3571-83.

Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes., Rex M, Hilton E, Old R., Int J Dev Biol. March 1, 2002; 46 (2): 217-26.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling., Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW., Genes Dev. April 1, 2002; 16 (7): 820-35.    

The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish., Poulain M, Lepage T., Development. November 1, 2002; 129 (21): 4901-14.

Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation., Branford WW, Yost HJ., Curr Biol. December 23, 2002; 12 (24): 2136-41.              

Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein., Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R., Int J Dev Biol. February 1, 2003; 47 (1): 15-29.                  

FRL-1, a member of the EGF-CFC family, is essential for neural differentiation in Xenopus early development., Yabe S, Tanegashima K, Haramoto Y, Takahashi S, Fujii T, Kozuma S, Taketani Y, Asashima M., Development. May 1, 2003; 130 (10): 2071-81.

Coordination of BMP-3b and cerberus is required for head formation of Xenopus embryos., Hino J, Nishimatsu S, Nagai T, Matsuo H, Kangawa K, Nohno T., Dev Biol. August 1, 2003; 260 (1): 138-57.                            

Endogenous Cerberus activity is required for anterior head specification in Xenopus., Silva AC, Filipe M, Kuerner KM, Steinbeisser H, Belo JA., Development. October 1, 2003; 130 (20): 4943-53.              

The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish., Trinh LA, Meyer D, Stainier DY., Development. October 1, 2003; 130 (20): 4989-98.

The maternally expressed zebrafish T-box gene eomesodermin regulates organizer formation., Bruce AE, Howley C, Zhou Y, Vickers SL, Silver LM, King ML, Ho RK., Development. November 1, 2003; 130 (22): 5503-17.

An SP1-like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction., Zhao J, Cao Y, Zhao C, Postlethwait J, Meng A., EMBO J. November 17, 2003; 22 (22): 6078-88.

Regulation of vertebrate eye development by Rx genes., Bailey TJ, El-Hodiri H, Zhang L, Shah R, Mathers PH, Jamrich M., Int J Dev Biol. January 1, 2004; 48 (8-9): 761-70.    

The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish., Hashimoto H, Rebagliati M, Ahmad N, Muraoka O, Kurokawa T, Hibi M, Suzuki T., Development. April 1, 2004; 131 (8): 1741-53.

ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus., Chen Y, Mironova E, Whitaker LL, Edwards L, Yost HJ, Ramsdell AF., Dev Biol. April 15, 2004; 268 (2): 280-94.      

Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus., Kuroda H, Wessely O, De Robertis EM., PLoS Biol. May 1, 2004; 2 (5): E92.                

Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling., Tanegashima K, Haramoto Y, Yokota C, Takahashi S, Asashima M., Int J Dev Biol. June 1, 2004; 48 (4): 275-83.          

Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish., Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW., Dev Biol. September 1, 2004; 273 (1): 23-37.

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis., Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W., Dev Cell. October 1, 2004; 7 (4): 525-34.                          

Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B., Piepenburg O, Grimmer D, Williams PH, Smith JC., Development. October 1, 2004; 131 (20): 4977-86.              

Xenopus nodal related-1 is indispensable only for left-right axis determination., Toyoizumi R, Ogasawara T, Takeuchi S, Mogi K., Int J Dev Biol. January 1, 2005; 49 (8): 923-38.                

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

xBtg-x regulates Wnt/beta-Catenin signaling during early Xenopus development., Wessely O, Kim JI, Tran U, Fuentealba L, De Robertis EM., Dev Biol. July 1, 2005; 283 (1): 17-28.              

Frodo proteins: modulators of Wnt signaling in vertebrate development., Brott BK, Sokol SY., Differentiation. September 1, 2005; 73 (7): 323-9.      

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo., Collart C, Verschueren K, Rana A, Smith JC, Huylebroeck D., Development. October 1, 2005; 132 (20): 4575-86.        

Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning., Houston DW, Wylie C., Development. November 1, 2005; 132 (21): 4845-55.              

SOX7 and SOX18 are essential for cardiogenesis in Xenopus., Zhang C, Basta T, Klymkowsky MW., Dev Dyn. December 1, 2005; 234 (4): 878-91.                    

XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning., Onuma Y, Yeo CY, Whitman M., Development. January 1, 2006; 133 (2): 237-50.                                      

Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus., Cha YR, Takahashi S, Wright CV., Dev Biol. February 15, 2006; 290 (2): 246-64.                        

A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos., Dorey K, Hill CS., Dev Biol. April 15, 2006; 292 (2): 303-16.  

FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development., Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS., Development. December 1, 2006; 133 (24): 4827-38.                    

Xenopus glucose transporter 1 (xGLUT1) is required for gastrulation movement in Xenopus laevis., Suzawa K, Yukita A, Hayata T, Goto T, Danno H, Michiue T, Cho KW, Asashima M., Int J Dev Biol. January 1, 2007; 51 (3): 183-90.              

Negative regulation of Activin/Nodal signaling by SRF during Xenopus gastrulation., Yun CH, Choi SC, Park E, Kim SJ, Chung AS, Lee HK, Lee HK, Lee HJ, Lee HJ, Han JK., Development. February 1, 2007; 134 (4): 769-77.              

FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula., Mir A, Kofron M, Zorn AM, Bajzer M, Haque M, Heasman J, Wylie CC., Development. February 1, 2007; 134 (4): 779-88.                  

PP2A:B56epsilon is required for eye induction and eye field separation., Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J., Dev Biol. February 15, 2007; 302 (2): 477-93.                  

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        

The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways., Yan B, Moody SA., Dev Biol. May 1, 2007; 305 (1): 103-19.        

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

The role of FoxC1 in early Xenopus development., Cha JY, Birsoy B, Kofron M, Mahoney E, Lang S, Wylie C, Heasman J., Dev Dyn. October 1, 2007; 236 (10): 2731-41.        

XSUMO-1 is required for normal mesoderm induction and axis elongation during early Xenopus development., Yukita A, Michiue T, Danno H, Asashima M., Dev Dyn. October 1, 2007; 236 (10): 2757-66.    

Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., Morris SA, Almeida AD, Tanaka H, Ohta K, Ohnuma S., PLoS One. October 10, 2007; 2 (10): e1004.                    

Two T-box genes play independent and cooperative roles to regulate morphogenesis of ciliated Kupffer's vesicle in zebrafish., Amack JD, Wang X, Yost HJ., Dev Biol. October 15, 2007; 310 (2): 196-210.    

Regulation of the response to Nodal-mediated mesoderm induction by Xrel3., Kennedy MW, Green KA, Ford RL, Andrews PG, Paterno GD, Gillespie LL, Kao KR., Dev Biol. November 15, 2007; 311 (2): 383-95.      

Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos., Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, De Robertis EM, Kuroda H., Mech Dev. January 1, 2008; 125 (1-2): 58-66.              

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling., Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M., Development. September 1, 2008; 135 (17): 2927-37.  

R-spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis Kazanskaya O, Glinka A, del BarcoBarrantes I, Stannek P, Niehrs C, Wu W, Division of Molecular Embryology, Deutsches Krebsforschungszentrum, Heidelberg, Germany., Koeneman KS., Urol Oncol. January 1, 2009; 27 (1):


Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis., Roel G, Gent YY, Peterson-Maduro J, Verbeek FJ, Destree O., Int J Dev Biol. January 1, 2009; 53 (1): 81-9.          

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos., Cheong SM, Kim H, Han JK., J Biol Chem. June 19, 2009; 284 (25): 17052-60.                        

Tumor necrosis factor-receptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation., Kalkan T, Iwasaki Y, Park CY, Thomsen GH., Mol Biol Cell. July 1, 2009; 20 (14): 3436-50.                          

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