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Summary Expression Phenotypes Gene Literature (69) GO Terms (42) Nucleotides (208) Proteins (41) Interactants (947) Wiki
XB-GENEPAGE-483305

Papers associated with cdx2



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Temporal induction of the homeodomain transcription factor Nkx2-1 is sufficient to respecify foregut and hindgut endoderm to a pulmonary fate in Xenopus laevis., Hyatt BA, Lundberg E, Eye R, Rankin SA, Zorn AM., MicroPubl Biol. May 7, 2025; 2025   

Urodele amphibian newt bridges the missing link in evo-devo of the pancreas., Morozumi R, Okamoto K, Enomoto E, Tsukamoto Y, Kyakuno M, Suzuki N, Tazawa I, Furuno N, Ogino H, Kamei Y, Matsunami M, Shigenobu S, Suzuki K, Uemasu H, Namba N, Hayashi T., Dev Dyn. January 8, 2025;


Histological and gene-expression analyses of pyloric sphincter formation during stomach metamorphosis in Xenopus laevis., Nagura K, Ikeda T, Hasebe T, Satou-Kobayashi Y, Udagawa S, Shigenobu S, Ishizuya-Oka A, Taira M., Dev Biol. September 21, 2024; 517 100-116.

Wnt signaling in cell adhesion, development, and colon cancer., Tejeda-Muñoz N, Mei KC., IUBMB Life. July 17, 2024; 76 (7): 383-396.   


A mathematical modelling portrait of Wnt signalling in early vertebrate embryogenesis., Giuraniuc CV, Zain S, Ghafoor S, Hoppler S., J Theor Biol. November 7, 2022; 551-552 111239.   


Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK., Nat Commun. November 5, 2022; 13 (1): 6681.   


Evo-Devo of Urbilateria and its larval forms., De Robertis EM, Tejeda-Muñoz N., Dev Biol. July 1, 2022; 487 10-20.   


A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.   


Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension., Mok GF, Folkes L, Weldon SA, Maniou E, Martinez-Heredia V, Godden AM, Williams RM, Sauka-Spengler T, Wheeler GN, Moxon S, Münsterberg AE., Nat Commun. February 19, 2021; 12 (1): 1157.   


Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Mukherjee S, Chaturvedi P, Rankin SA, Rankin SA, Fish MB, Wlizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KW, Zorn AM., Elife. September 7, 2020; 9   


Chromatin accessibility and histone acetylation in the regulation of competence in early development., Esmaeili M, Blythe SA, Tobias JW, Zhang K, Yang J, Klein PS., Dev Biol. June 1, 2020; 462 (1): 20-35.   


Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos., Lichtig H, Artamonov A, Polevoy H, Reid CD, Bielas SL, Frank D., Front Physiol. January 1, 2020; 11 75.   


Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. January 1, 2020;   


Integration of Wnt and FGF signaling in the Xenopus gastrula at TCF and Ets binding sites shows the importance of short-range repression by TCF in patterning the marginal zone., Kjolby RAS, Truchado-Garcia M, Iruvanti S, Harland RM., Development. August 9, 2019; 146 (15):   


Ventx1.1 competes with a transcriptional activator Xcad2 to regulate negatively its own expression., Kumar S, Kumar S, Umair Z, Kumar V, Lee U, Choi SC, Kim J., BMB Rep. June 1, 2019; 52 (6): 403-408.   


Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Paraiso KD, Blitz IL, Zhou JJ, Cho KWY., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.   


Ventx1.1 as a Direct Repressor of Early Neural Gene zic3 in Xenopus laevis., Umair Z, Kumar S, Kim DH, Rafiq K, Kumar V, Kim S, Park JB, Lee JY, Lee U, Kim J., Mol Cells. December 31, 2018; 41 (12): 1061-1071.   


Increasing complexity: Mechanical guidance and feedback loops as a basis for self-organization in morphogenesis., Bredov D, Volodyaev I., Biosystems. November 1, 2018; 173 133-156.

The Xenopus animal cap transcriptome: building a mucociliary epithelium., Angerilli A, Smialowski P, Rupp RA., Nucleic Acids Res. September 28, 2018; 46 (17): 8772-8787.   


Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14., Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A., Dev Growth Differ. April 1, 2018; 60 (3): 158-173.   


Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus., Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC., Dev Cell. March 12, 2018; 44 (5): 597-610.e10.   


Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.   


Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord., Steventon B, Martinez Arias A., Dev Biol. December 1, 2017; 432 (1): 3-13.

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.   


Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.   


Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation., Kjolby RAS, Harland RM., Dev Biol. June 15, 2017; 426 (2): 165-175.   


Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.   


Eomesodermin-At Dawn of Cell Fate Decisions During Early Embryogenesis., Probst S, Arnold SJ., Curr Top Dev Biol. January 1, 2017; 122 93-115.

Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules., Nakamura Y, de Paiva Alves E, Veenstra GJ, Hoppler S., Development. June 1, 2016; 143 (11): 1914-25.   


Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis., Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, Yamauchi K., Cell Biosci. January 21, 2016; 6 2.   


Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution., Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW., BMC Biol. August 1, 2015; 13 56.   


A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A, Liu B, Liang H, Wei C, Guindani M, Lu Y, Liang S, St John LS, Molldrem J, Nagarajan L., Oncotarget. December 30, 2014; 5 (24): 12675-93.   


Getting to know your neighbor: cell polarization in early embryos., Nance J., J Cell Biol. September 29, 2014; 206 (7): 823-32.   


Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.   


Molecular insights into the origin of the Hox-TALE patterning system., Hudry B, Thomas-Chollier M, Volovik Y, Duffraisse M, Dard A, Frank D, Technau U, Merabet S., Elife. March 18, 2014; 3 e01939.   


A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance., Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S, Bradley M, Nichols J, Ko MSH, Brickman JM., Curr Biol. November 18, 2013; 23 (22): 2233-2244.   


Single blastomere expression profiling of Xenopus laevis embryos of 8 to 32-cells reveals developmental asymmetry., Flachsova M, Sindelka R, Kubista M., Sci Rep. January 1, 2013; 3 2278.   


fus/TLS orchestrates splicing of developmental regulators during gastrulation., Dichmann DS, Harland RM., Genes Dev. June 15, 2012; 26 (12): 1351-63.   


Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos., Zhao H, Han D, Dawid IB, Pieler T, Chen Y., Proc Natl Acad Sci U S A. May 29, 2012; 109 (22): 8594-9.   


Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency., Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MS, Ptashne M, Brickman JM., Cell Rep. February 23, 2012; 1 (2): 99-109.   


Identification and characterization of Xenopus kctd15, an ectodermal gene repressed by the FGF pathway., Takahashi C, Suzuki T, Nishida E, Kusakabe M., Int J Dev Biol. January 1, 2012; 56 (5): 393-402.   


Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro., Spence JR, Mayhew CN, Rankin SA, Rankin SA, Kuhar MF, Vallance JE, Tolle K, Hoskins EE, Kalinichenko VV, Wells SI, Zorn AM, Shroyer NF, Wells JM., Nature. February 3, 2011; 470 (7332): 105-9.   


The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex., Guo RJ, Funakoshi S, Lee HH, Lee HH, Kong J, Lynch JP., Carcinogenesis. February 1, 2010; 31 (2): 159-66.   


Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis., Faas L, Isaacs HV., Dev Dyn. April 1, 2009; 238 (4): 835-52.   


Cloning and expression analysis of the anterior parahox genes, Gsh1 and Gsh2 from Xenopus tropicalis., Illes JC, Winterbottom E, Isaacs HV., Dev Dyn. January 1, 2009; 238 (1): 194-203.   


Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning., Ambrosio AL, Taelman VF, Lee HX, Lee HX, Metzinger CA, Coffinier C, De Robertis EM., Dev Cell. August 1, 2008; 15 (2): 248-60.   


Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M, Sauka-Spengler T, Nicolle D, Le-Mentec C, Lallemand Y, Da Silva C, Plouhinec JL, Robert B, Wincker P, Shi DL, Mazan S., PLoS One. April 18, 2007; 2 (4): e374.   


Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.   


FGF signal transduction and the regulation of Cdx gene expression., Keenan ID, Sharrard RM, Isaacs HV., Dev Biol. November 15, 2006; 299 (2): 478-88.   

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