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Summary Expression Phenotypes Gene Literature (34) GO Terms (7) Nucleotides (87) Proteins (43) Interactants (290) Wiki
XB--483369

Papers associated with gem



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Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem-implications for channelopathies., Allam S, Levenson-Palmer R, Chia Chang Z, Kaur S, Cernuda B, Raman A, Booth A, Dobbins S, Suppa G, Yang J, Buraei Z., Front Physiol. January 1, 2023; 14 1155976.        

Direct inhibition of CaV2.3 by Gem is dynamin dependent and does not require a direct alfa/beta interaction., Contreras GF, Saavedra J, Navarro-Quezada N, Mellado G, Gonzalez C, Neely A., Biochem Biophys Res Commun. January 1, 2022; 586 107-113.          

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts., Larsen NB, Gao AO, Sparks JL, Gallina I, Wu RA, Mann M, Räschle M, Walter JC, Duxin JP., Mol Cell. February 7, 2019; 73 (3): 574-588.e7.                

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression., Aze A, Sannino V, Soffientini P, Bachi A, Costanzo V., Nat Cell Biol. June 1, 2016; 18 (6): 684-91.        

Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link., Budzowska M, Graham TG, Sobeck A, Waga S, Walter JC., EMBO J. July 14, 2015; 34 (14): 1971-85.

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters., Johnson ZL, Lee JH, Lee K, Lee M, Kwon DY, Hong J, Lee SY., Elife. July 31, 2014; 3 e03604.                        

Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly., Soto X, Li J, Lea R, Dubaissi E, Papalopulu N, Amaya E., Proc Natl Acad Sci U S A. July 2, 2013; 110 (27): 11029-34.                                      

Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes., Klein SL, Neilson KM, Orban J, Yaklichkin S, Hoffbauer J, Mood K, Daar IO, Moody SA., PLoS One. April 4, 2013; 8 (4): e61845.                  

Molecular determinants of Gem protein inhibition of P/Q-type Ca2+ channels., Fan M, Zhang WK, Buraei Z, Yang J., J Biol Chem. June 29, 2012; 287 (27): 22749-58.

Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate., Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA., Dev Biol. May 15, 2012; 365 (2): 363-75.                        

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition., Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ., PLoS One. January 1, 2012; 7 (5): e38009.                        

The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module., Rogers CD, Ferzli GS, Casey ES., BMC Dev Biol. January 26, 2011; 11 74.        

Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation., Schäfer A, Schomacher L, Barreto G, Döderlein G, Niehrs C., PLoS One. November 19, 2010; 5 (11): e14060.            

Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction., Fan M, Buraei Z, Luo HR, Levenson-Palmer R, Yang J., Proc Natl Acad Sci U S A. August 17, 2010; 107 (33): 14887-92.

Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila., Herr A, Mckenzie L, Suryadinata R, Sadowski M, Parsons LM, Sarcevic B, Richardson HE., Dev Biol. August 1, 2010; 344 (1): 36-51.

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.        

RGK GTPase-dependent CaV2.1 Ca2+ channel inhibition is independent of CaVbeta-subunit-induced current potentiation., Leyris JP, Gondeau C, Charnet A, Delattre C, Rousset M, Cens T, Charnet P., FASEB J. August 1, 2009; 23 (8): 2627-38.

foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation., Yan B, Neilson KM, Moody SA., Dev Biol. May 1, 2009; 329 (1): 80-95.              

Replication initiation complex formation in the absence of nuclear function in Xenopus., Krasinska L, Fisher D., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.            

Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives., Rogers CD, Harafuji N, Archer T, Cunningham DD, Casey ES., Mech Dev. January 1, 2009; 126 (1-2): 42-55.        

Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.              

Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1., Nakagomi-Hagihara R, Nakai D, Tokui T, Abe T, Ikeda T., Xenobiotica. May 1, 2007; 37 (5): 474-86.

Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases., Seu L, Pitt GS., J Gen Physiol. November 1, 2006; 128 (5): 605-13.          

Subcellular translocation signals regulate Geminin activity during embryonic development., Boos A, Lee A, Thompson DM, Kroll KL., Biol Cell. June 1, 2006; 98 (6): 363-75.

Tcf- and Vent-binding sites regulate neural-specific geminin expression in the gastrula embryo., Taylor JJ, Wang T, Kroll KL., Dev Biol. January 15, 2006; 289 (2): 494-506.                

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity., Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL., Genes Dev. July 15, 2005; 19 (14): 1723-34.      

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

Direct interaction of geminin and Six3 in eye development., Del Bene F, Tessmar-Raible K, Wittbrodt J., Nature. February 19, 2004; 427 (6976): 745-9.

Identification of protein kinase C (PKC) isoforms in teleostean, amphibian and avian pigment cells., Isoldi MC, Matioli SR, Castrucci AM, de Lima LH, Visconti MA, Rebouças NA., Pigment Cell Res. December 1, 2003; 16 (6): 639-43.

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts., Stokes MP, Van Hatten R, Lindsay HD, Michael WM., J Cell Biol. September 2, 2002; 158 (5): 863-72.        

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis., Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.    

Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem., Béguin P, Nagashima K, Gonoi T, Shibasaki T, Takahashi K, Kashima Y, Ozaki N, Geering K, Iwanaga T, Seino S., Nature. June 7, 2001; 411 (6838): 701-6.

Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation., Kroll KL, Salic AN, Evans LM, Kirschner MW., Development. August 1, 1998; 125 (16): 3247-58.                

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