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Summary Expression Phenotypes Gene Literature (200) GO Terms (6) Nucleotides (59) Proteins (39) Interactants (186) Wiki
XB-GENEPAGE-483959

Papers associated with kcnj1



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Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation., Rangel-Garcia CI, Salvador C, Chavez-Garcia K, Diaz-Bello B, Lopez-Gonzalez Z, Vazquez-Cruz L, Angel Vazquez-Martinez J, Ortiz-Navarrete V, Riveros-Rosas H, Escobar LI., FEBS Open Bio. April 1, 2021; 11 (4): 1093-1108.            

Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis., Louis-Dit-Picard H, Kouranti I, Rafael C, Loisel-Ferreira I, Chavez-Canales M, Abdel-Khalek W, Argaiz ER, Baron S, Vacle S, Migeon T, Coleman R, Do Cruzeiro M, Hureaux M, Thurairajasingam N, Decramer S, Girerd X, O'Shaugnessy K, Mulatero P, Roussey G, Tack I, Unwin R, Vargas-Poussou R, Staub O, Grimm R, Welling PA, Gamba G, Clauser E, Hadchouel J, Jeunemaitre X., J Clin Invest. December 1, 2020; 130 (12): 6379-6394.

ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation., Murthy M, Kurz T, O'Shaughnessy KM., Physiol Rep. July 1, 2016; 4 (13):             

Non-basic amino acids in the ROMK1 channels via an appropriate distance modulate PIP2 regulated pHi-gating., Lee CH, Lee CH, Huang PT, Liou HH, Lin MY, Lou KL, Chen CY., Biochem Biophys Res Commun. April 22, 2016; 473 (1): 303-310.

Direct injection of cell-free Kir1.1 protein into Xenopus oocytes replicates single-channel currents derived from Kir1.1 mRNA., Sackin H, Nanazashvili M, Makino S., Channels (Austin). January 1, 2015; 9 (4): 196-9.        

Pregabalin activates ROMK1 channels via cAMP-dependent protein kinase and protein kinase C., Lee CH, Lee CH, Liou HH., Eur J Pharmacol. October 5, 2014; 740 35-44.

State-dependent network connectivity determines gating in a K+ channel., Bollepalli MK, Fowler PW, Rapedius M, Shang L, Sansom MS, Tucker SJ, Baukrowitz T., Structure. July 8, 2014; 22 (7): 1037-46.              

SPAK and OSR1 dependent down-regulation of murine renal outer medullary K channel ROMK1., Elvira B, Munoz C, Borras J, Chen H, Warsi J, Ajay SS, Shumilina E, Lang F., Kidney Blood Press Res. January 1, 2014; 39 (4): 353-60.

Insights into the structural nature of the transition state in the Kir channel gating pathway., Fowler PW, Bollepalli MK, Rapedius M, Nematian-Ardestani E, Shang L, Sansom MS, Tucker SJ, Baukrowitz T., Channels (Austin). January 1, 2014; 8 (6): 551-5.    

Identification of compound heterozygous KCNJ1 mutations (encoding ROMK) in a kindred with Bartter's syndrome and a functional analysis of their pathogenicity., Srivastava S, Li D, Edwards N, Hynes AM, Wood K, Al-Hamed M, Wroe AC, Reaich D, Moochhala SH, Welling PA, Sayer JA., Physiol Rep. November 1, 2013; 1 (6): e00160.          

WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway., Yue P, Zhang C, Lin DH, Sun P, Wang WH., Biochim Biophys Acta. October 1, 2013; 1833 (10): 2101-10.

Inhibition of ROMK channels by low extracellular K+ and oxidative stress., Frindt G, Li H, Sackin H, Palmer LG., Am J Physiol Renal Physiol. July 15, 2013; 305 (2): F208-15.

Downregulation of the renal outer medullary K(+) channel ROMK by the AMP-activated protein kinase., Siraskar B, Huang DY, Pakladok T, Siraskar G, Sopjani M, Alesutan I, Kucherenko Y, Almilaji A, Devanathan V, Shumilina E, Föller M, Munoz C, Lang F., Pflugers Arch. February 1, 2013; 465 (2): 233-45.

Interactions of external K+ and internal blockers in a weak inward-rectifier K+ channel., Yang L, Edvinsson J, Palmer LG., J Gen Physiol. November 1, 2012; 140 (5): 529-40.                

Protein kinase C mediated pH(i)-regulation of ROMK1 channels via a phosphatidylinositol-4,5-bisphosphate-dependent mechanism., Huang PT, Lee CH, Lee CH, Liou HH, Lou KL., J Mol Model. July 1, 2012; 18 (7): 2929-41.

Aquaporin-2: new mutations responsible for autosomal-recessive nephrogenic diabetes insipidus-update and epidemiology., Bichet DG, El Tarazi A, Matar J, Lussier Y, Arthus MF, Lonergan M, Bockenhauer D, Bissonnette P., Clin Kidney J. June 1, 2012; 5 (3): 195-202.          

Ion selectivity and current saturation in inward-rectifier K+ channels., Yang L, Edvinsson J, Sackin H, Palmer LG., J Gen Physiol. February 1, 2012; 139 (2): 145-57.                    

Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1., Raphemot R, Lonergan DF, Nguyen TT, Utley T, Lewis LM, Kadakia R, Weaver CD, Gogliotti R, Hopkins C, Lindsley CW, Denton JS., Front Pharmacol. November 30, 2011; 2 75.              

Functional and developmental expression of a zebrafish Kir1.1 (ROMK) potassium channel homologue Kcnj1., Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT, White SJ., J Physiol. March 15, 2011; 589 (Pt 6): 1489-503.

Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes., Pearl EJ, Jarikji Z, Horb ME., Dev Biol. March 1, 2011; 351 (1): 135-45.                    

Inhibition of g protein-activated inwardly rectifying k channels by phencyclidine., Kobayashi T, Nishizawa D, Ikeda K., Curr Neuropharmacol. March 1, 2011; 9 (1): 244-6.    

Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange., Alper SL, Stewart AK, Vandorpe DH, Clark JS, Horack RZ, Simpson JE, Walker NM, Clarke LL., Am J Physiol Cell Physiol. February 1, 2011; 300 (2): C276-86.

Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function., Renigunta A, Renigunta V, Saritas T, Decher N, Mutig K, Waldegger S., J Biol Chem. January 21, 2011; 286 (3): 2224-35.

Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel., Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS., Mol Pharmacol. January 1, 2011; 79 (1): 42-50.

The glycolytic enzymes glyceraldehyde 3-phosphate dehydrogenase and enolase interact with the renal epithelial K+ channel ROMK2 and regulate its function., Renigunta A, Mutig K, Rottermann K, Schlichthörl G, Preisig-Müller R, Daut J, Waldegger S, Renigunta V., Cell Physiol Biochem. January 1, 2011; 28 (4): 663-72.

Hypertension resistance polymorphisms in ROMK (Kir1.1) alter channel function by different mechanisms., Fang L, Li D, Welling PA., Am J Physiol Renal Physiol. December 1, 2010; 299 (6): F1359-64.

Magnesium modulates ROMK channel-mediated potassium secretion., Yang L, Frindt G, Palmer LG., J Am Soc Nephrol. December 1, 2010; 21 (12): 2109-16.

Effects of dietary K on cell-surface expression of renal ion channels and transporters., Frindt G, Palmer LG., Am J Physiol Renal Physiol. October 1, 2010; 299 (4): F890-7.

Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct., Lu M, Dong K, Egan ME, Giebisch GH, Boulpaep EL, Hebert SC., Proc Natl Acad Sci U S A. March 30, 2010; 107 (13): 6082-7.

Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop., Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I., Channels (Austin). January 1, 2010; 4 (1): 63-6.

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1., Agrawal R, Tran U, Wessely O., Development. December 1, 2009; 136 (23): 3927-36.              

POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels., Lin DH, Yue P, Pan CY, Sun P, Zhang X, Han Z, Roos M, Caplan M, Giebisch G, Wang WH., J Biol Chem. October 23, 2009; 284 (43): 29614-24.

An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1., Sackin H, Nanazashvili M, Li H, Palmer LG, Walters DE., Biophys J. August 19, 2009; 97 (4): 1058-66.

Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3., Kobayashi T, Washiyama K, Ikeda K., PLoS One. July 21, 2009; 4 (7): e6311.              

Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel., Furutani K, Ohno Y, Inanobe A, Hibino H, Kurachi Y., Mol Pharmacol. June 1, 2009; 75 (6): 1287-95.

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway., San-Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G., Proc Natl Acad Sci U S A. March 17, 2009; 106 (11): 4384-9.

Structural changes in the cytoplasmic pore of the Kir1.1 channel during pHi-gating probed by FRET., Lee JR, Shieh RC., J Biomed Sci. March 6, 2009; 16 29.      

Dietary K regulates ROMK channels in connecting tubule and cortical collecting duct of rat kidney., Frindt G, Shah A, Edvinsson J, Palmer LG., Am J Physiol Renal Physiol. February 1, 2009; 296 (2): F347-54.

WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway., Zhang W, Na T, Peng JB., Am J Physiol Renal Physiol. November 1, 2008; 295 (5): F1472-84.

The acidic motif of WNK4 is crucial for its interaction with the K channel ROMK., Murthy M, Cope G, O'Shaughnessy KM., Biochem Biophys Res Commun. October 31, 2008; 375 (4): 651-4.

Functional and structural characterization of PKA-mediated pHi gating of ROMK1 channels., Lee CH, Lee CH, Huang PT, Lou KL, Liou HH., J Mol Graph Model. October 1, 2008; 27 (3): 332-41.

PKA-mediated phosphorylation is a novel mechanism for levetiracetam, an antiepileptic drug, activating ROMK1 channels., Lee CH, Lee CH, Lee CY, Lee CY, Tsai TS, Liou HH., Biochem Pharmacol. July 15, 2008; 76 (2): 225-35.

d-Amphetamine inhibits inwardly rectifying potassium channels in Xenopus oocytes expression system., Lee CH, Lee CH, Liou HH, Lu KL, Shen YC, Tsai MC., Neurotoxicology. July 1, 2008; 29 (4): 638-46.

Gabapentin activates ROMK1 channels by a protein kinase A (PKA)-dependent mechanism., Lee CH, Lee CH, Tsai TS, Liou HH., Br J Pharmacol. May 1, 2008; 154 (1): 216-25.

Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels., Lin D, Kamsteeg EJ, Zhang Y, Jin Y, Sterling H, Yue P, Roos M, Duffield A, Spencer J, Caplan M, Wang WH., J Biol Chem. March 21, 2008; 283 (12): 7674-81.

Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        

H bonding at the helix-bundle crossing controls gating in Kir potassium channels., Rapedius M, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T., Neuron. August 16, 2007; 55 (4): 602-14.                

Xenopus Bicaudal-C is required for the differentiation of the amphibian pronephros., Tran U, Pickney LM, Ozpolat BD, Wessely O., Dev Biol. July 1, 2007; 307 (1): 152-64.                  

Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes., Kobayashi T, Nishizawa D, Iwamura T, Ikeda K., Toxicol In Vitro. June 1, 2007; 21 (4): 656-64.

Inhibitor of growth 4 (ING4) is up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation., Zhang X, Lin DH, Jin Y, Wang KS, Zhang Y, Babilonia E, Wang Z, Wang Z, Giebisch G, Han ZG, Wang WH., Proc Natl Acad Sci U S A. May 29, 2007; 104 (22): 9517-22.

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