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Summary Expression Phenotypes Gene Literature (71) GO Terms (9) Nucleotides (150) Proteins (67) Interactants (330) Wiki
XB-GENEPAGE-484494

Papers associated with pdgfa



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[Growth factors and embryonic development]., Evain-Brion D., Reprod Nutr Dev. January 1, 1988; 28 (6B): 1681-6.

Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos., Mercola M, Melton DA, Stiles CD., Science. September 2, 1988; 241 (4870): 1223-5.

Regulation of c-fos messenger ribonucleic acid by fibroblast growth factor in cultured Sertoli cells., Smith EP, Hall SH, Monaco L, French FS, Wilson EM, Conti M., Ann N Y Acad Sci. January 1, 1989; 564 132-9.

Expression of biologically active human platelet-derived growth factor (PDGF) B-receptor in Xenopus laevis oocytes., Gassmann M, Hosang M, Mous J., Biochem Biophys Res Commun. January 15, 1990; 166 (1): 154-9.

Effects of cell heterogeneity on production of polypeptide growth factors and mesoderm-inducing activity by Xenopus laevis XTC cells., Snoek GT, Koster CH, de Laat SW, Heideveld M, Durston AJ, van Zoelen EJ., Exp Cell Res. April 1, 1990; 187 (2): 203-10.

Dominant-negative mutants of a platelet-derived growth factor gene., Mercola M, Deininger PL, Shamah SM, Porter J, Wang CY, Stiles CD., Genes Dev. December 1, 1990; 4 (12B): 2333-41.

Growth-factor-related proteins that are inducers in early amphibian development may mediate similar steps in amniote (bird) embryogenesis., Cooke J, Wong A., Development. January 1, 1991; 111 (1): 197-212.

Recombinant PDGF from lower vertebrates: receptor binding and immunochemical analysis with metabolically labeled growth factor., Wang C, Shamah SM, Stiles CD., Growth Factors. January 1, 1992; 7 (4): 279-88.

Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells., Heldin P, Asplund T, Ytterberg D, Thelin S, Laurent TC., Biochem J. April 1, 1992; 283 ( Pt 1) 165-70.

Platelet-derived growth factor and alternative splicing: a review., Khachigian LM, Chesterman CN., Pathology. October 1, 1992; 24 (4): 280-90.

The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression., Jones SD, Ho L, Smith JC, Yordan C, Stiles CD, Mercola M., Dev Genet. January 1, 1993; 14 (3): 185-93.

Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes., Stefani M, Caselli A, Bucciantini M, Pazzagli L, Dolfi F, Camici G, Manao G, Ramponi G., FEBS Lett. July 12, 1993; 326 (1-3): 131-4.

Dominant-negative mutations of platelet-derived growth factor (PDGF) receptors. Inhibition of receptor function by ligand-dependent formation of heterodimers between PDGF alpha- and beta-receptors., Ueno H, Escobedo JA, Williams LT., J Biol Chem. October 25, 1993; 268 (30): 22814-9.

Selectivity of phospholipase C isozymes in growth factor signaling., Cho YS, Han MK, Chae SW, Park CU, Kim UH., FEBS Lett. November 22, 1993; 334 (3): 257-60.

Injection of bovine parathyroid poly(A)+ RNA into Xenopus oocytes confers sensitivity to high extracellular calcium., Chen TH, Pratt SA, Shoback DM., J Bone Miner Res. February 1, 1994; 9 (2): 293-300.

Modulation of a voltage-activated potassium channel by peptide growth factor receptors., Timpe LC, Fantl WJ., J Neurosci. March 1, 1994; 14 (3 Pt 1): 1195-201.

A rapid bioassay for platelet-derived growth factor beta-receptor tyrosine kinase function., Graminski GF, Lerner MR., Biotechnology (N Y). October 1, 1994; 12 (10): 1008-11.

Identification and partial characterization of the c-jun oncogene in Xenopus laevis., Lazarus P, Calcagnotto A., Cancer Lett. November 11, 1994; 86 (2): 201-8.

Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells., Ho L, Symes K, Yordán C, Gudas LJ, Mercola M., Mech Dev. December 1, 1994; 48 (3): 165-74.

Presynaptic differentiation induced in cultured neurons by local application of basic fibroblast growth factor., Dai Z, Peng HB., J Neurosci. August 1, 1995; 15 (8): 5466-75.

PDGF signalling is required for gastrulation of Xenopus laevis., Ataliotis P, Symes K, Chou MM, Ho L, Mercola M., Development. September 1, 1995; 121 (9): 3099-110.                  

Platelet-derived growth factor receptor is a novel modulator of type A gamma-aminobutyric acid-gated ion channels., Valenzuela CF, Kazlauskas A, Brozowski SJ, Weiner JL, Demali KA, McDonald BJ, Moss SJ, Dunwiddie TV, Harris RA., Mol Pharmacol. December 1, 1995; 48 (6): 1099-107.

Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function., Valenzuela CF, Xiong Z, MacDonald JF, Weiner JL, Frazier CJ, Dunwiddie TV, Kazlauskas A, Whiting PJ, Harris RA., J Biol Chem. July 5, 1996; 271 (27): 16151-9.

Immunocytochemical evidence of PDGF- and TGF-beta-like molecules in invertebrate and vertebrate immunocytes: an evolutionary approach., Franchini A, Kletsas D, Ottaviani E., Histochem J. September 1, 1996; 28 (9): 599-605.

Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase., Symes K, Mercola M., Proc Natl Acad Sci U S A. September 3, 1996; 93 (18): 9641-4.

Cyclic AMP inhibitors inhibits PDGF-stimulated mitogen-activated protein kinase activity in rat aortic smooth muscle cells via inactivation of c-Raf-1 kinase and induction of MAP kinase phosphatase-1., Plevin R, Malarkey K, Aidulis D, McLees A, Gould GW., Cell Signal. January 1, 1997; 9 (3-4): 323-8.

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment., Yang J, Symes K, Mercola M, Schreiber SL., Curr Biol. January 1, 1998; 8 (1): 11-8.

Evidence that platelet derived growth factor (PDGF) action is required for mesoderm patterning in early amphibian (Xenopus laevis) embryogenesis., Ghil JS, Chung HM., Int J Dev Biol. July 1, 1999; 43 (4): 329-34.

An analysis of the early events when oligodendrocyte precursor cells are triggered to differentiate by thyroid hormone, retinoic acid, or PDGF withdrawal., Tokumoto YM, Durand B, Raff MC., Dev Biol. September 15, 1999; 213 (2): 327-39.

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase., Yoshii S, Tanaka M, Otsuki Y, Wang DY, Guo RJ, Zhu Y, Takeda R, Hanai H, Kaneko E, Sugimura H., Oncogene. October 7, 1999; 18 (41): 5680-90.

Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta., Runft LL, Watras J, Jaffe LA., Dev Biol. October 15, 1999; 214 (2): 399-411.

Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo., Umbhauer M, Penzo-Méndez A, Clavilier L, Boucaut J, Riou J., J Cell Sci. August 1, 2000; 113 ( Pt 16) 2865-75.

Signal transduction pathways triggered by fibroblast growth factor receptor 1 expressed in Xenopus laevis oocytes after fibroblast growth factor 1 addition. Role of Grb2, phosphatidylinositol 3-kinase, Src tyrosine kinase, and phospholipase Cgamma., Browaeys-Poly E, Cailliau K, Vilain JP., Eur J Biochem. October 1, 2000; 267 (20): 6256-63.

Expression regulation of hyaluronan synthase in corneal endothelial cells., Usui T, Amano S, Oshika T, Suzuki K, Miyata K, Araie M, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. October 1, 2000; 41 (11): 3261-7.

Sequence and translation initiation properties of the xenopus TGFbeta5, PDGF-A, and PDGF-alpha receptor 5' untranslated regions., van der Velden AW, Los A, Voorma HO, Thomas AA., Int J Dev Biol. December 1, 2000; 44 (8): 851-9.

RasGAP is involved in signal transduction triggered by FGF1 in Xenopus oocytes expressing FGFR1., Cailliau K, Browaeys-Poly E, Vilain JP., FEBS Lett. May 11, 2001; 496 (2-3): 161-5.

Characterization and expression of three forms of cDNA encoding chicken platelet-derived growth factor-A chain., Horiuchi H, Inoue T, Furusawa S, Matsuda H., Gene. July 11, 2001; 272 (1-2): 181-90.

Platelet-derived growth factor stimulates the formation of versican-hyaluronan aggregates and pericellular matrix expansion in arterial smooth muscle cells., Evanko SP, Johnson PY, Braun KR, Underhill CB, Dudhia J, Wight TN., Arch Biochem Biophys. October 1, 2001; 394 (1): 29-38.

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase., Dorey K, Engen JR, Kretzschmar J, Wilm M, Neubauer G, Schindler T, Superti-Furga G., Oncogene. December 6, 2001; 20 (56): 8075-84.

BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells., Fiedler J, Röderer G, Günther KP, Brenner RE., J Cell Biochem. January 1, 2002; 87 (3): 305-12.

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis., Furstoss O, Dorey K, Simon V, Barilà D, Superti-Furga G, Roche S., EMBO J. February 15, 2002; 21 (4): 514-24.

Expression of hyaluronan synthase in intraocular proliferative diseases: regulation of expression in human vascular endothelial cells by transforming growth factor-beta., Suzuki K, Yamamoto T, Usui T, Suzuki K, Heldin P, Yamashita H., Jpn J Ophthalmol. January 1, 2003; 47 (6): 557-64.

PDGF upregulates delayed rectifier via Src family kinases and sphingosine kinase in oligodendroglial progenitors., Soliven B, Ma L, Bae H, Attali B, Sobko A, Iwase T., Am J Physiol Cell Physiol. January 1, 2003; 284 (1): C85-93.

Hyaluronan synthase in trabecular meshwork cells., Usui T, Nakajima F, Ideta R, Kaji Y, Suzuki Y, Araie M, Miyauchi S, Heldin P, Yamashita H., Br J Ophthalmol. March 1, 2003; 87 (3): 357-60.

Platelet-derived growth factor signaling as a cue of the epithelial-mesenchymal interaction required for anuran skin metamorphosis., Utoh R, Shigenaga S, Watanabe Y, Yoshizato K., Dev Dyn. June 1, 2003; 227 (2): 157-69.              

Roles of PDGF in animal development., Hoch RV, Soriano P., Development. October 1, 2003; 130 (20): 4769-84.            

The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation., Van Stry M, McLaughlin KA, Ataliotis P, Symes K., Dev Biol. April 1, 2004; 268 (1): 232-42.          

Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling., Nagel M, Tahinci E, Symes K, Winklbauer R., Development. June 1, 2004; 131 (11): 2727-36.    

High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene., Bruna A, Darken RS, Rojo F, Ocaña A, Peñuelas S, Arias A, Paris R, Tortosa A, Mora J, Baselga J, Seoane J., Cancer Cell. February 1, 2007; 11 (2): 147-60.

Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases., Taruno A, Niisato N, Marunaka Y., Am J Physiol Renal Physiol. July 1, 2007; 293 (1): F128-38.

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