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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB-GENEPAGE-485219

Papers associated with otx2



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Neural induction by the secreted polypeptide noggin., Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM., Science. October 29, 1993; 262 (5134): 713-8.

The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions., Pannese M, Polo C, Andreazzoli M, Vignali R, Kablar B, Barsacchi G, Boncinelli E., Development. March 1, 1995; 121 (3): 707-20.                      

Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle., Blitz IL, Cho KW., Development. April 1, 1995; 121 (4): 993-1004.              

Patterning of the neural ectoderm of Xenopus laevis by the amino-terminal product of hedgehog autoproteolytic cleavage., Lai CJ, Ekker SC, Beachy PA, Moon RT., Development. August 1, 1995; 121 (8): 2349-60.            

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos., Dominguez I, Itoh K, Sokol SY., Proc Natl Acad Sci U S A. August 29, 1995; 92 (18): 8498-502.            

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern., Lamb TM, Harland RM., Development. November 1, 1995; 121 (11): 3627-36.          

Specification of the anteroposterior neural axis through synergistic interaction of the Wnt signaling cascade with noggin and follistatin., McGrew LL, Lai CJ, Moon RT., Dev Biol. November 1, 1995; 172 (1): 337-42.    

Caudalization of neural fate by tissue recombination and bFGF., Cox WG, Hemmati-Brivanlou A., Development. December 1, 1995; 121 (12): 4349-58.                

Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase., Itoh K, Tang TL, Neel BG, Sokol SY., Development. December 1, 1995; 121 (12): 3979-88.              

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction., Hawley SH, Wünnenberg-Stapleton K, Hashimoto C, Laurent MN, Watabe T, Blumberg BW, Cho KW., Genes Dev. December 1, 1995; 9 (23): 2923-35.                

A sticky problem: the Xenopus cement gland as a paradigm for anteroposterior patterning., Sive H, Bradley L., Dev Dyn. March 1, 1996; 205 (3): 265-80.          

Xotx genes in the developing brain of Xenopus laevis., Kablar B, Vignali R, Menotti L, Pannese M, Andreazzoli M, Polo C, Giribaldi MG, Boncinelli E, Barsacchi G., Mech Dev. April 1, 1996; 55 (2): 145-58.

Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus., Pierce SB, Kimelman D., Dev Biol. May 1, 1996; 175 (2): 256-64.          

A functional homologue of goosecoid in Drosophila., Goriely A, Stella M, Coffinier C, Kessler D, Mailhos C, Dessain S, Desplan C., Development. May 1, 1996; 122 (5): 1641-50.    

Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox., Schmidt JE, von Dassow G, Kimelman D., Development. June 1, 1996; 122 (6): 1711-21.                    

A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm., Papalopulu N, Kintner C., Development. November 1, 1996; 122 (11): 3409-18.            

Analysis of Dishevelled signalling pathways during Xenopus development., Sokol SY., Curr Biol. November 1, 1996; 6 (11): 1456-67.                  

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus., Pownall ME, Tucker AS, Slack JM, Isaacs HV., Development. December 1, 1996; 122 (12): 3881-92.                  

Graded amounts of Xenopus dishevelled specify discrete anteroposterior cell fates in prospective ectoderm., Itoh K, Sokol SY., Mech Dev. January 1, 1997; 61 (1-2): 113-25.

Identification of otx2 target genes and restrictions in ectodermal competence during Xenopus cement gland formation., Gammill LS, Sive H., Development. January 1, 1997; 124 (2): 471-81.          

An essential role for retinoid signaling in anteroposterior neural patterning., Blumberg B, Bolado J, Moreno TA, Kintner C, Evans RM, Papalopulu N., Development. January 1, 1997; 124 (2): 373-9.        

Transcription factors and head formation in vertebrates., Bally-Cuif L, Boncinelli E., Bioessays. February 1, 1997; 19 (2): 127-35.

Expression of murine Lhx5 suggests a role in specifying the forebrain., Sheng HZ, Bertuzzi S, Chiang C, Shawlot W, Taira M, Dawid I, Westphal H., Dev Dyn. February 1, 1997; 208 (2): 266-77.

XIPOU 2 is a potential regulator of Spemann's Organizer., Witta SE, Sato SM., Development. March 1, 1997; 124 (6): 1179-89.                

Cellular and molecular interactions in the development of the Xenopus olfactory system., Reiss JO, Burd GD., Semin Cell Dev Biol. April 1, 1997; 8 (2): 171-9.            

Activating and repressing signals in head development: the role of Xotx1 and Xotx2., Andreazzoli M, Pannese M, Boncinelli E., Development. May 1, 1997; 124 (9): 1733-43.                

Xwnt-8 and lithium can act upon either dorsal mesodermal or neurectodermal cells to cause a loss of forebrain in Xenopus embryos., Fredieu JR, Cui Y, Maier D, Danilchik MV, Christian JL., Dev Biol. June 1, 1997; 186 (1): 100-14.                

Markers of vertebrate mesoderm induction., Stennard F, Ryan K, Gurdon JB., Curr Opin Genet Dev. October 1, 1997; 7 (5): 620-7.

Patterning of the embryo along the anterior-posterior axis: the role of the caudal genes., Epstein M, Pillemer G, Yelin R, Yisraeli JK, Fainsod A., Development. October 1, 1997; 124 (19): 3805-14.                

Anf: a novel class of vertebrate homeobox genes expressed at the anterior end of the main embryonic axis., Kazanskaya OV, Severtzova EA, Barth KA, Ermakova GV, Lukyanov SA, Benyumov AO, Pannese M, Boncinelli E, Wilson SW, Zaraisky AG., Gene. October 24, 1997; 200 (1-2): 25-34.    

Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus., McGrew LL, Hoppler S, Moon RT., Mech Dev. December 1, 1997; 69 (1-2): 105-14.          

The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins., Latinkić BV, Umbhauer M, Neal KA, Lerchner W, Smith JC, Cunliffe V., Genes Dev. December 1, 1997; 11 (23): 3265-76.              

Xenopus hindbrain patterning requires retinoid signaling., Kolm PJ, Apekin V, Sive H., Dev Biol. December 1, 1997; 192 (1): 1-16.              

Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a., Saint-Jeannet JP, He X, Varmus HE, Dawid IB., Proc Natl Acad Sci U S A. December 9, 1997; 94 (25): 13713-8.            

The Spemann organizer of Xenopus is patterned along its anteroposterior axis at the earliest gastrula stage., Zoltewicz JS, Gerhart JC., Dev Biol. December 15, 1997; 192 (2): 482-91.          

Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system., Shi DL, Goisset C, Boucaut JC., Mech Dev. January 1, 1998; 70 (1-2): 35-47.                    

The role of intracellular alkalinization in the establishment of anterior neural fate in Xenopus., Uzman JA, Patil S, Uzgare AR, Sater AK., Dev Biol. January 1, 1998; 193 (1): 10-20.              

Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification., Bellefroid EJ, Kobbe A, Gruss P, Pieler T, Gurdon JB, Papalopulu N., EMBO J. January 2, 1998; 17 (1): 191-203.            

Midkine counteracts the activin signal in mesoderm induction and promotes neural formation., Yokota C, Takahashi S, Eisaki A, Asashima M, Akhter S, Muramatsu T, Kadomatsu K., J Biochem. February 1, 1998; 123 (2): 339-46.

Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction., Mizuseki K, Kishi M, Matsui M, Nakanishi S, Sasai Y., Development. February 1, 1998; 125 (4): 579-87.              

Inhibition of retinoic acid receptor-mediated signalling alters positional identity in the developing hindbrain., van der Wees J, Schilthuis JG, Koster CH, Diesveld-Schipper H, Folkers GE, van der Saag PT, Dawson MI, Shudo K, van der Burg B, Durston AJ., Development. February 1, 1998; 125 (3): 545-56.              

XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues., Frisch A, Wright CV., Development. February 1, 1998; 125 (3): 431-42.                  

Murine cerberus homologue mCer-1: a candidate anterior patterning molecule., Biben C, Stanley E, Fabri L, Kotecha S, Rhinn M, Drinkwater C, Lah M, Wang CC, Nash A, Hilton D, Ang SL, Mohun T, Harvey RP., Dev Biol. February 15, 1998; 194 (2): 135-51.    

Anterior specification of embryonic ectoderm: the role of the Xenopus cement gland-specific gene XAG-2., Aberger F, Weidinger G, Grunz H, Richter K., Mech Dev. March 1, 1998; 72 (1-2): 115-30.              

The Xenopus Emx genes identify presumptive dorsal telencephalon and are induced by head organizer signals., Pannese M, Lupo G, Kablar B, Boncinelli E, Barsacchi G, Vignali R., Mech Dev. April 1, 1998; 73 (1): 73-83.                

Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex., Nothias F, Fishell G, Ruiz i Altaba A., Curr Biol. April 9, 1998; 8 (8): 459-62.  

Expression of the mouse cerberus-related gene, Cerr1, suggests a role in anterior neural induction and somitogenesis., Shawlot W, Deng JM, Behringer RR., Proc Natl Acad Sci U S A. May 26, 1998; 95 (11): 6198-203.

A role for Xenopus Frizzled 8 in dorsal development., Itoh K, Jacob J, Y Sokol S., Mech Dev. June 1, 1998; 74 (1-2): 145-57.  

Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer., Casellas R, Brivanlou AH., Dev Biol. June 1, 1998; 198 (1): 1-12.                

Xenopus eomesodermin is expressed in neural differentiation., Ryan K, Butler K, Bellefroid E, Gurdon JB., Mech Dev. July 1, 1998; 75 (1-2): 155-8.    

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