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ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation. , Wang C , Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y , Qi X, Cai D, Mao B , Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H ., EMBO Rep. February 1, 2024; 25 (2): 646-671.
Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis. , Saumweber E, Mzoughi S, Khadra A, Werberger A, Schumann S, Guccione E, Schmeisser MJ, Kühl SJ ., Front Cell Dev Biol. January 1, 2024; 12 1316048.
Head organizer: Cerberus and IGF cooperate in brain induction in Xenopus embryos. , Azbazdar Y, Pera EM , De Robertis EM ., Cells Dev. December 16, 2023; 203897.
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. , Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK ., Nat Commun. November 5, 2022; 13 (1): 6681.
HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs. , Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q , Xi Q., Cell Rep. July 12, 2022; 40 (2): 111038.
Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease. , Walentek P ., Cells Tissues Organs. January 1, 2022; 211 (6): 736-753.
Smad2 and Smad3 differentially modulate chordin transcription via direct binding on the distal elements in gastrula Xenopus embryos. , Kumar V , Umair Z, Kumar S , Kumar S , Lee U, Kim J ., Biochem Biophys Res Commun. June 25, 2021; 559 168-175.
The Multifaceted Roles of USP15 in Signal Transduction. , Das T, Song EJ, Kim EE ., Int J Mol Sci. April 29, 2021; 22 (9):
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage. , Castro Colabianchi AM, Tavella MB, Boyadjián López LE, Rubinstein M, Franchini LF, López SL ., Biol Open. February 25, 2021; 10 (2):
Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos. , Umair Z, Kumar S , Rafiq K , Kumar V , Reman ZU, Lee SH, Kim S, Lee JY , Lee U, Kim J ., Anim Cells Syst (Seoul). November 27, 2020; 24 (6): 359-370.
Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling. , Reich S, Kayastha P, Teegala S , Weinstein DC ., BMC Mol Cell Biol. May 28, 2020; 21 (1): 39.
Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm. , Reich S, Weinstein DC ., Genes (Basel). November 6, 2019; 10 (11):
Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis. , Piprek RP, Damulewicz M, Tassan JP , Kloc M , Kubiak JZ ., Dev Genes Evol. May 1, 2019; 229 (2-3): 53-72.
Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. , Watanabe T, Yamamoto T , Tsukano K, Hirano S, Horikawa A, Michiue T ., Development. October 26, 2018; 145 (20):
Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells. , Zhang Z , Lei A, Xu L, Chen L, Chen Y , Chen Y , Zhang X, Gao Y, Yang X, Zhang M, Cao Y , Cao Y ., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.
Eomesodermin-At Dawn of Cell Fate Decisions During Early Embryogenesis. , Probst S, Arnold SJ., Curr Top Dev Biol. January 1, 2017; 122 93-115.
Aberrant regulation of Wnt signaling in hepatocellular carcinoma. , Liu LJ, Xie SX, Chen YT , Xue JL, Zhang CJ, Zhu F., World J Gastroenterol. September 7, 2016; 22 (33): 7486-99.
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. , Raymond A, Liu B, Liang H, Wei C, Guindani M, Lu Y, Liang S, St John LS, Molldrem J, Nagarajan L., Oncotarget. December 30, 2014; 5 (24): 12675-93.
Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm. , Nordin K, LaBonne C ., Dev Cell. November 10, 2014; 31 (3): 374-382.
The tumor suppressor Smad4/ DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling. , Demagny H, Araki T, De Robertis EM ., Cell Rep. October 23, 2014; 9 (2): 688-700.
Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos. , Kirmizitas A, Gillis WQ, Zhu H, Thomsen GH ., Dev Biol. August 15, 2014; 392 (2): 358-67.
Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus. , Young JJ , Kjolby RA, Kong NR, Monica SD, Harland RM ., Development. April 1, 2014; 141 (8): 1683-93.
A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome. , Tanaka K, Kato A, Angelocci C, Watanabe M, Kato Y ., Dev Biol. March 1, 2014; 387 (1): 28-36.
Commitment to nutritional endoderm in Eleutherodactylus coqui involves altered nodal signaling and global transcriptional repression. , Chatterjee S, Elinson RP ., J Exp Zool B Mol Dev Evol. January 1, 2014; 322 (1): 27-44.
Brain-specific promoter/exon I.f of the cyp19a1 ( aromatase) gene in Xenopus laevis. , Nakagawa T, Iwabuchi J., J Steroid Biochem Mol Biol. November 1, 2012; 132 (3-5): 247-55.
Signaling crosstalk between TGFβ and Dishevelled/ Par1b. , Mamidi A, Inui M, Manfrin A, Soligo S, Enzo E, Aragona M, Cordenonsi M, Wessely O , Dupont S, Piccolo S ., Cell Death Differ. October 1, 2012; 19 (10): 1689-97.
Self-regulation of the head-inducing properties of the Spemann organizer. , Inui M, Montagner M, Ben-Zvi D, Martello G , Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S ., Proc Natl Acad Sci U S A. September 18, 2012; 109 (38): 15354-9.
Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4. , Warmflash A, Zhang Q , Sorre B, Vonica A , Siggia ED, Brivanlou AH ., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): E1947-56.
Bmp indicator mice reveal dynamic regulation of transcriptional response. , Javier AL, Doan LT, Luong M, Reyes de Mochel NS, Sun A, Monuki ES, Cho KW ., PLoS One. January 1, 2012; 7 (9): e42566.
USP15 is a deubiquitylating enzyme for receptor-activated SMADs. , Inui M, Manfrin A, Mamidi A, Martello G , Morsut L, Soligo S, Enzo E, Moro S, Polo S, Dupont S, Cordenonsi M, Piccolo S ., Nat Cell Biol. September 25, 2011; 13 (11): 1368-75.
HEB and E2A function as SMAD/FOXH1 cofactors. , Yoon SJ , Wills AE , Chuong E, Gupta R , Baker JC ., Genes Dev. August 1, 2011; 25 (15): 1654-61.
Role of BMP, FGF, calcium signaling, and Zic proteins in vertebrate neuroectodermal differentiation. , Aruga J , Mikoshiba K ., Neurochem Res. July 1, 2011; 36 (7): 1286-92.
SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. , Wu MY, Ramel MC, Howell M, Hill CS ., PLoS Biol. February 15, 2011; 9 (2): e1000593.
Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning. , Kozmikova I, Smolikova J, Vlcek C, Kozmik Z., PLoS One. February 3, 2011; 6 (2): e14650.
ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. , Masserdotti G, Badaloni A, Green YS, Croci L, Barili V, Bergamini G, Vetter ML , Consalez GG., J Biol Chem. October 1, 2010; 285 (40): 30814-24.
The BMP pathway acts to directly regulate Tbx20 in the developing heart. , Mandel EM , Kaltenbrun E, Callis TE, Zeng XX, Marques SR, Yelon D, Wang DZ, Conlon FL ., Development. June 1, 2010; 137 (11): 1919-29.
TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. , Watanabe Y, Itoh S, Goto T , Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H , Ten Dijke P, Kato M., Mol Cell. January 15, 2010; 37 (1): 123-34.
Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus. , Hagemann AI, Xu X, Nentwich O, Hyvonen M, Smith JC ., Development. August 1, 2009; 136 (16): 2803-13.
High-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferases. , Hida N, Awais M, Takeuchi M, Ueno N , Tashiro M, Takagi C, Singh T, Hayashi M, Ohmiya Y, Ozawa T., PLoS One. June 12, 2009; 4 (6): e5868.
Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif. , Makkar P, Metpally RP , Sangadala S, Reddy BV., J Mol Graph Model. April 1, 2009; 27 (7): 803-12.
FAM/ USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. , Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello G , Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N, Argenton F, Newfeld SJ, Piccolo S ., Cell. January 9, 2009; 136 (1): 123-35.
TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways. , Tacheau C, Fontaine J, Loy J, Mauviel A, Verrecchia F., J Cell Physiol. December 1, 2008; 217 (3): 759-68.
Generation of mice with a conditional allele for Trim33. , Kim J , Kaartinen V., Genesis. June 1, 2008; 46 (6): 329-33.
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. , Monzen K, Ito Y , Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M , Nagai R, Komuro I., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.
HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus. , Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R., J Biol Chem. April 25, 2008; 283 (17): 11841-9.
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. , Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D , Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM., Mol Cell Biol. January 1, 2008; 28 (1): 248-57.
Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. , Pinho S, Niehrs C ., Differentiation. December 1, 2007; 75 (10): 957-67.
Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. , Saka Y , Hagemann AI, Piepenburg O, Smith JC ., Development. December 1, 2007; 134 (23): 4209-18.
Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain. , Dai F, Chang C , Lin X, Dai P, Mei L, Feng XH., Mol Cell Biol. September 1, 2007; 27 (17): 6183-94.
Negative regulation of Activin/ Nodal signaling by SRF during Xenopus gastrulation. , Yun CH, Choi SC, Park E, Kim SJ, Chung AS, Lee HK , Lee HK , Lee HJ , Lee HJ , Han JK ., Development. February 1, 2007; 134 (4): 769-77.