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Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. , Rosa FM., Cell. June 16, 1989; 57 (6): 965-74.
Regulatory interactions during embryogenesis in Xenopus laevis. , Dawid IB , Otani H, Curtiss P, Taira M ., C R Acad Sci III. September 1, 1993; 316 (9): 945-58.
Mesoderm induction by activin requires FGF-mediated intracellular signals. , LaBonne C , Whitman M ., Development. February 1, 1994; 120 (2): 463-72.
Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern. , Green JB , Smith JC , Gerhart JC ., Development. August 1, 1994; 120 (8): 2271-8.
FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction. , Cornell RA, Musci TJ , Kimelman D ., Development. August 1, 1995; 121 (8): 2429-37.
Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development. , Re'em-Kalma Y, Lamb T, Frank D ., Proc Natl Acad Sci U S A. December 19, 1995; 92 (26): 12141-5.
DNA sequences mediating the transcriptional response of the Mix.2 homeobox gene to mesoderm induction. , Vize PD ., Dev Biol. July 10, 1996; 177 (1): 226-31.
BMP-4-responsive regulation of dorsal- ventral patterning by the homeobox protein Mix.1. , Mead PE , Brivanlou IH, Kelley CM , Zon LI ., Nature. July 25, 1996; 382 (6589): 357-60.
An experimental system for analyzing response to a morphogen gradient. , Gurdon JB , Mitchell A, Ryan K., Proc Natl Acad Sci U S A. September 3, 1996; 93 (18): 9334-8.
A transcriptional partner for MAD proteins in TGF-beta signalling. , Chen X, Rubock MJ, Whitman M ., Nature. October 24, 1996; 383 (6602): 691-6.
Eomesodermin, a key early gene in Xenopus mesoderm differentiation. , Ryan K, Garrett N, Mitchell A, Gurdon JB ., Cell. December 13, 1996; 87 (6): 989-1000.
Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling. , LaBonne C , Whitman M ., Dev Biol. March 1, 1997; 183 (1): 9-20.
Markers of vertebrate mesoderm induction. , Stennard F , Ryan K, Gurdon JB ., Curr Opin Genet Dev. October 1, 1997; 7 (5): 620-7.
The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. , Latinkić BV, Umbhauer M , Neal KA, Lerchner W, Smith JC , Cunliffe V., Genes Dev. December 1, 1997; 11 (23): 3265-76.
Characterization of CMIX, a chicken homeobox gene related to the Xenopus gene mix.1. , Peale FV, Sugden L, Bothwell M., Mech Dev. July 1, 1998; 75 (1-2): 167-70.
A role for the vegetally expressed Xenopus gene Mix.1 in endoderm formation and in the restriction of mesoderm to the marginal zone. , Lemaire P , Darras S, Caillol D, Kodjabachian L ., Development. July 1, 1998; 125 (13): 2371-80.
The role of maternal VegT in establishing the primary germ layers in Xenopus embryos. , Zhang J, Houston DW , King ML , Payne C, Wylie C , Heasman J ., Cell. August 21, 1998; 94 (4): 515-24.
Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. , Mead PE , Zhou Y, Lustig KD , Huber TL, Kirschner MW , Zon LI ., Proc Natl Acad Sci U S A. September 15, 1998; 95 (19): 11251-6.
Goosecoid and mix.1 repress Brachyury expression and are required for head formation in Xenopus. , Latinkic BV , Smith JC ., Development. April 1, 1999; 126 (8): 1769-79.
A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos. , Gamer LW, Wolfman NM, Celeste AJ, Hattersley G, Hewick R, Rosen V., Dev Biol. April 1, 1999; 208 (1): 222-32.
Promoter activity of the zebrafish bhikhari retroelement requires an intact activin signaling pathway. , Vogel AM, Gerster T., Mech Dev. July 1, 1999; 85 (1-2): 133-46.
A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos. , Yasuo H, Lemaire P ., Curr Biol. August 26, 1999; 9 (16): 869-79.
Mml, a mouse Mix-like gene expressed in the primitive streak. , Pearce JJ, Evans MJ., Mech Dev. September 1, 1999; 87 (1-2): 189-92.
Neuralization of the Xenopus embryo by inhibition of p300/ CREB-binding protein function. , Kato Y , Shi Y , Shi Y , He X ., J Neurosci. November 1, 1999; 19 (21): 9364-73.
Single cells can sense their position in a morphogen gradient. , Gurdon JB , Standley H, Dyson S, Butler K, Langon T, Ryan K, Stennard F , Shimizu K, Zorn A ., Development. December 1, 1999; 126 (23): 5309-17.
Cngsc, a homologue of goosecoid, participates in the patterning of the head, and is expressed in the organizer region of Hydra. , Broun M, Sokol S , Bode HR., Development. December 1, 1999; 126 (23): 5245-54.
Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB. , Nagarajan RP, Chen F, Li W , Vig E, Harrington MA, Nakshatri H, Chen Y ., Biochem J. June 15, 2000; 348 Pt 3 591-6.
Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription. , Nagarajan RP, Chen Y ., Biochem J. August 15, 2000; 350 Pt 1 253-9.
Development and control of tissue separation at gastrulation in Xenopus. , Wacker S, Grimm K, Joos T, Winklbauer R ., Dev Biol. August 15, 2000; 224 (2): 428-39.
Cloning, expression analysis, and chromosomal localization of murine and human homologues of a Xenopus mix gene. , Robb L, Hartley L, Begley CG, Brodnicki TC, Copeland NG, Gilbert DJ, Jenkins NA, Elefanty AG., Dev Dyn. December 1, 2000; 219 (4): 497-504.
FGF signaling restricts the primary blood islands to ventral mesoderm. , Kumano G , Smith WC ., Dev Biol. December 15, 2000; 228 (2): 304-14.
Making mesoderm--upstream and downstream of Xbra. , Smith JC ., Int J Dev Biol. January 1, 2001; 45 (1): 219-24.
The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/ nodal signaling. , Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW ., Genes Dev. April 1, 2002; 16 (7): 820-35.
Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus. , Eimon PM, Harland RM ., Development. July 1, 2002; 129 (13): 3089-103.
A human Mix-like homeobox gene MIXL shows functional similarity to Xenopus Mix.1. , Guo W, Chan AP, Liang H, Wieder ED, Molldrem JJ, Etkin LD , Nagarajan L., Blood. July 1, 2002; 100 (1): 89-95.
Molecular regulation of vertebrate early endoderm development. , Shivdasani RA ., Dev Biol. September 15, 2002; 249 (2): 191-203.
Molecular components of the endoderm specification pathway in Xenopus tropicalis. , D'Souza A, Lee M, Taverner N, Mason J, Carruthers S , Smith JC , Amaya E , Papalopulu N , Zorn AM ., Dev Dyn. January 1, 2003; 226 (1): 118-27.
Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling. , Yamamoto S, Hikasa H, Ono H, Taira M ., Dev Biol. May 1, 2003; 257 (1): 190-204.
Selective degradation of excess Ldb1 by Rnf12/ RLIM confers proper Ldb1 expression levels and Xlim-1/ Ldb1 stoichiometry in Xenopus organizer functions. , Hiratani I, Yamamoto N, Mochizuki T, Ohmori SY, Taira M ., Development. September 1, 2003; 130 (17): 4161-75.
Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis. , Davidson LA , Keller R , DeSimone D ., Gene Expr Patterns. July 1, 2004; 4 (4): 457-66.
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. , Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S ., Cell. January 28, 2005; 120 (2): 223-35.
The ARID domain protein dril1 is necessary for TGF(beta) signaling in Xenopus embryos. , Callery EM , Smith JC , Thomsen GH ., Dev Biol. February 15, 2005; 278 (2): 542-59.
Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. , Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M, Piccolo S ., Cell. April 8, 2005; 121 (1): 87-99.
Determination of the minimal domains of Mix.3/ Mixer required for endoderm development. , Doherty JR, Zhu H, Kuliyev E, Mead PE ., Mech Dev. January 1, 2006; 123 (1): 56-66.
Global analysis of the transcriptional network controlling Xenopus endoderm formation. , Sinner D , Kirilenko P, Rankin S , Rankin S , Wei E, Howard L, Kofron M , Heasman J , Woodland HR , Zorn AM ., Development. May 1, 2006; 133 (10): 1955-66.
A role for GATA factors in Xenopus gastrulation movements. , Fletcher G, Jones GE, Patient R , Snape A., Mech Dev. October 1, 2006; 123 (10): 730-45.
Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia. , Glaser S, Metcalf D, Wu L, Hart AH, DiRago L, Mifsud S, D'Amico A, Dagger S, Campo C, Chan AC, Izon DJ, Robb L., Proc Natl Acad Sci U S A. October 31, 2006; 103 (44): 16460-5.
Amino terminal tyrosine phosphorylation of human MIXL1. , Guo W, Nagarajan L., J Mol Signal. December 5, 2006; 1 6.
Xenopus Dab2 is required for embryonic angiogenesis. , Cheong SM, Choi SC, Han JK ., BMC Dev Biol. December 19, 2006; 6 63.
Xenopus glucose transporter 1 (xGLUT1) is required for gastrulation movement in Xenopus laevis. , Suzawa K , Yukita A, Hayata T, Goto T , Danno H, Michiue T , Cho KW , Asashima M ., Int J Dev Biol. January 1, 2007; 51 (3): 183-90.