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Summary Expression Phenotypes Gene Literature (677) GO Terms (3) Nucleotides (94) Proteins (51) Interactants (1024) Wiki
XB--485904

Papers associated with ins (and Disease Ontology)



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Amphibian host-defense peptides with potential for Type 2 diabetes therapy - an updated review., Conlon JM, Owolabi BO, Flatt PR, Abdel-Wahab YHA., Peptides. May 1, 2024; 175 171180.  

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates., Szenker-Ravi E, Ott T, Khatoo M, Moreau de Bellaing A, Goh WX, Chong YL, Beckers A, Kannesan D, Louvel G, Anujan P, Ravi V, Bonnard C, Moutton S, Schoen P, Fradin M, Colin E, Megarbane A, Daou L, Chehab G, Di Filippo S, Rooryck C, Deleuze JF, Boland A, Arribard N, Eker R, Tohari S, Ng AY, Rio M, Lim CT, Eisenhaber B, Eisenhaber F, Venkatesh B, Amiel J, Crollius HR, Gordon CT, Gossler A, Roy S, Attie-Bitach T, Blum M, Bouvagnet P, Reversade B., Nat Genet. January 1, 2022; 54 (1): 62-72.

Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease., Han C, Sun Y, Yang Q, Zhou F, Chen X, Wu L, Sun L, Han J., Mol Pharm. August 2, 2021; 18 (8): 2906-2923.

Functional rice with tandemly repeated Cbl-b ubiquitin ligase inhibitory pentapeptide prevents denervation-induced muscle atrophy in vivo., Akama K, Shimajiri Y, Kainou K, Iwasaki R, Nakao R, Nikawa T, Nishikawa A., Biosci Biotechnol Biochem. May 25, 2021; 85 (6): 1415-1421.

Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study., Musale V, Moffett RC, Conlon JM, Flatt PR, Abdel-Wahab YH., Peptides. February 1, 2021; 136 170472.

Genetic and Physiological Effects of Insulin on Human Urate Homeostasis., Mandal AK, Leask MP, Estiverne C, Choi HK, Merriman TR, Mount DB., Front Physiol. January 1, 2021; 12 713710.              

Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M., Horm Res Paediatr. January 1, 2020; 93 (1): 16-29.

Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Usal M, Regnault C, Veyrenc S, Couturier K, Batandier C, Bulteau AL, Lejon D, Combourieu B, Lafond T, Raveton M, Reynaud S., Sci Total Environ. November 1, 2019; 689 149-159.

Binding of sulphonylureas to plasma proteins - A KATP channel perspective., Proks P, Kramer H, Haythorne E, Ashcroft FM., PLoS One. May 15, 2018; 13 (5): e0197634.        

Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline., Regnault C, Usal M, Veyrenc S, Couturier K, Batandier C, Bulteau AL, Lejon D, Sapin A, Combourieu B, Chetiveaux M, Le May C, Lafond T, Raveton M, Reynaud S., Proc Natl Acad Sci U S A. May 8, 2018; 115 (19): E4416-E4425.        

A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals., Zhang Y, Qin C, Yang L, Lu R, Zhao X, Nie G., BMC Genomics. April 11, 2018; 19 (1): 246.          

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes., Babiker T, Vedovato N, Patel K, Thomas N, Finn R, Männikkö R, Chakera AJ, Flanagan SE, Shepherd MH, Ellard S, Ashcroft FM, Hattersley AT., Diabetologia. June 1, 2016; 59 (6): 1162-6.    

Xenopus as a model system for studying pancreatic development and diabetes., Kofent J, Spagnoli FM., Semin Cell Dev Biol. March 1, 2016; 51 106-16.  

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T, Fisher M, Fisher M, Nakajima K, Odeleye AO, Zimmerman KB, Fish MB, Yaoita Y, Chojnowski JL, Lauderdale JD, Netland PA, Grainger RM., Dev Biol. December 15, 2015; 408 (2): 328-44.                              

Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB., J Recept Signal Transduct Res. January 1, 2015; 35 (6): 516-22.

Recessive mutations in PCBD1 cause a new type of early-onset diabetes., Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K., Diabetes. October 1, 2014; 63 (10): 3557-64.

Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells., Oropeza D, Horb M., Genesis. March 1, 2012; 50 (3): 271-85.                        

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity., Hertel J, Struthers H, Horj CB, Hruz PW., J Biol Chem. December 31, 2004; 279 (53): 55147-52.

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities., Delobel P, Flament S, Hamdane M, Delacourte A, Vilain JP, Buée L., FEBS Lett. April 10, 2002; 516 (1-3): 151-5.

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