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Summary Expression Phenotypes Gene Literature (57) GO Terms (11) Nucleotides (146) Proteins (39) Interactants (349) Wiki
XB--486066

Papers associated with bax



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A calmodulin-target peptide hybrid molecule with unique calcium-binding properties., Porumb T, Yau P, Harvey TS, Ikura M., Protein Eng. January 1, 1994; 7 (1): 109-15.

Apoptosis in Xenopus tadpole tail muscles involves Bax-dependent pathways., Sachs LM, Abdallah B, Hassan A, Levi G, De Luze A, Reed JC, Demeneix BA., FASEB J. August 1, 1997; 11 (10): 801-8.

Regulation of apoptosis by BH3 domains in a cell-free system., Cosulich SC, Worrall V, Hedge PJ, Green S, Clarke PR., Curr Biol. December 1, 1997; 7 (12): 913-20.

Refolding, purification, and characterization of a loop deletion mutant of human Bcl-2 from bacterial inclusion bodies., Anderson M, Blowers D, Hewitt N, Hedge P, Breeze A, Hampton I, Taylor I., Protein Expr Purif. March 1, 1999; 15 (2): 162-70.

NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump., Elshorst B, Hennig M, Försterling H, Diener A, Maurer M, Schulte P, Schwalbe H, Griesinger C, Krebs J, Schmid H, Vorherr T, Carafoli E., Biochemistry. September 21, 1999; 38 (38): 12320-32.

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol., Kluck RM, Esposti MD, Perkins G, Renken C, Kuwana T, Bossy-Wetzel E, Goldberg M, Allen T, Barber MJ, Green DR, Newmeyer DD., J Cell Biol. November 15, 1999; 147 (4): 809-22.                    

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release., von Ahsen O, Renken C, Perkins G, Kluck RM, Bossy-Wetzel E, Newmeyer DD., J Cell Biol. September 4, 2000; 150 (5): 1027-36.                  

Cell cycle transitions in early Xenopus development., Maller JL, Gross SD, Schwab MS, Finkielstein CV, Taieb FE, Qian YW., Novartis Found Symp. January 1, 2001; 237 58-73; discussion 73-8.

The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage., Finkielstein CV, Lewellyn AL, Maller JL., Proc Natl Acad Sci U S A. January 30, 2001; 98 (3): 1006-11.            

Xenopus Bcl-X(L) selectively protects Rohon-Beard neurons from metamorphic degeneration., Coen L, du Pasquier D, Le Mevel S, Brown S, Tata J, Mazabraud A, Demeneix BA., Proc Natl Acad Sci U S A. July 3, 2001; 98 (14): 7869-74.

Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells., Kanovsky M, Raffo A, Drew L, Rosal R, Do T, Friedman FK, Rubinstein P, Visser J, Robinson R, Brandt-Rauf PW, Michl J, Fine RL, Pincus MR., Proc Natl Acad Sci U S A. October 23, 2001; 98 (22): 12438-43.

Interaction between the antiapoptotic protein Nr-13 and cytochrome c. Antagonistic effect of the BH3 domain of Bax., Moradi-Améli M, Lorca T, Ficheux D, di Pietro A, Gillet G., Biochemistry. July 9, 2002; 41 (27): 8540-50.

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane., Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R, Green DR, Newmeyer DD., Cell. November 1, 2002; 111 (3): 331-42.

Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription., Howell M, Borchers C, Milgram SL., J Biol Chem. June 18, 2004; 279 (25): 26300-6.

A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest., Tríbulo C, Aybar MJ, Sánchez SS, Mayor R., Dev Biol. November 15, 2004; 275 (2): 325-42.

Implication of bax in Xenopus laevis tail regression at metamorphosis., Sachs LM, Le Mevel S, Demeneix BA., Dev Dyn. December 1, 2004; 231 (4): 671-82.          

Apoptosis of tail muscle during amphibian metamorphosis involves a caspase 9-dependent mechanism., Rowe I, Le Blay K, Du Pasquier D, Palmier K, Levi G, Demeneix B, Coen L., Dev Dyn. May 1, 2005; 233 (1): 76-87.

Apoptosis effects of Xrel3 c-Rel/Nuclear Factor-kappa B homolog in human cervical cancer cells., Shehata M, Shehata M, Shehata F, Pater A., Cell Biol Int. June 1, 2005; 29 (6): 429-40.

Developmental cell death during Xenopus metamorphosis involves BID cleavage and caspase 2 and 8 activation., Du Pasquier D, Rincheval V, Sinzelle L, Chesneau A, Ballagny C, Sachs LM, Demeneix B, Mazabraud A., Dev Dyn. August 1, 2006; 235 (8): 2083-94.                  

tBid mediated activation of the mitochondrial death pathway leads to genetic ablation of the lens in Xenopus laevis., Du Pasquier D, Chesneau A, Ymlahi-Ouazzani Q, Boistel R, Pollet N, Ballagny C, Sachs LM, Demeneix B, Mazabraud A., Genesis. January 1, 2007; 45 (1): 1-10.            

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak., Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM., J Cell Biol. April 23, 2007; 177 (2): 277-87.              

Survival factor withdrawal-induced apoptosis of TF-1 cells involves a TRB2-Mcl-1 axis-dependent pathway., Lin KR, Lee SF, Hung CM, Li CL, Yang-Yen HF, Yen JJ., J Biol Chem. July 27, 2007; 282 (30): 21962-72.

Differential subcellular sequestration of proapoptotic and antiapoptotic proteins and colocalization of Bcl-x(L) with the germ plasm, in Xenopus laevis oocytes., Kloc M, Shirato Y, Bilinski S, Browder LW, Johnston J., Genesis. August 1, 2007; 45 (8): 523-31.          

Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus., Nichane M, Ren X, Souopgui J, Bellefroid EJ., Dev Biol. October 15, 2008; 322 (2): 368-80.                        

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation., Schafer B, Quispe J, Choudhary V, Chipuk JE, Ajero TG, Du H, Schneiter R, Kuwana T., Mol Biol Cell. April 1, 2009; 20 (8): 2276-85.

Effects of the anthelmintic drug PF1022A on mammalian tissue and cells., Dornetshuber R, Kamyar MR, Rawnduzi P, Baburin I, Kouri K, Pilz E, Hornbogen T, Zocher R, Berger W, Lemmens-Gruber R., Biochem Pharmacol. April 15, 2009; 77 (8): 1437-44.

p27(BBP)/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development., De Marco N, Iannone L, Carotenuto R, Biffo S, Vitale A, Campanella C., Cell Death Differ. February 1, 2010; 17 (2): 360-72.

Polypyrimidine tract-binding protein is required for the repression of gene expression by all-trans retinoic acid., Tamanoue Y, Yamagishi M, Hongo I, Okamoto H., Dev Growth Differ. June 1, 2010; 52 (5): 469-79.                    

Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect., Peixoto PM, Lue JK, Ryu SY, Wroble BN, Sible JC, Kinnally KW., Am J Pathol. January 1, 2011; 178 (1): 48-54.

Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK., Du Pasquier D, Dupré A, Jessus C., PLoS One. January 1, 2011; 6 (8): e23672.              

Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53., Rana AA, Roper SJ, Palmer EA, Smith JC., N Biotechnol. July 1, 2011; 28 (4): 334-41.                

Eukaryotic initiation factor 6 (eif6) overexpression affects eye development in Xenopus laevis., De Marco N, Tussellino M, Vitale A, Campanella C., Differentiation. September 1, 2011; 82 (2): 108-15.          

ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus., Tríbulo C, Guadalupe Barrionuevo M, Agüero TH, Sánchez SS, Calcaterra NB, Aybar MJ., Dev Dyn. February 1, 2012; 241 (2): 257-69.            

Examining BCL-2 family function with large unilamellar vesicles., Asciolla JJ, Renault TT, Chipuk JE., J Vis Exp. October 5, 2012; (68):


Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes., Gillies LA, Du H, Peters B, Knudson CM, Newmeyer DD, Kuwana T., Mol Biol Cell. January 15, 2015; 26 (2): 339-49.          

Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          

Recovery capabilities of Xenopus laevis after exposure to Cadmium and Zinc., Mouchet F, Teaniniuraitemoana V, Baudrimont M, Daffe G, Gauthier L, Gonzalez P., Chemosphere. November 1, 2015; 139 117-25.

Dehydration triggers differential microRNA expression in Xenopus laevis brain., Luu BE, Storey KB., Gene. November 15, 2015; 573 (1): 64-9.

Transcriptomic Responses During Early Development Following Arsenic Exposure in Western Clawed Frogs, Silurana tropicalis., Zhang J, Koch I, Gibson LA, Loughery JR, Martyniuk CJ, Button M, Caumette G, Reimer KJ, Cullen WR, Langlois VS., Toxicol Sci. December 1, 2015; 148 (2): 603-17.

Alterations in gene expression levels provide early indicators of chemical stress during Xenopus laevis embryo development: A case study with perfluorooctane sulfonate (PFOS)., San-Segundo L, Guimarães L, Fernández Torija C, Beltrán EM, Guilhermino L, Pablos MV., Ecotoxicol Environ Saf. May 1, 2016; 127 51-60.

Overexpressed targeting protein for Xklp2 (TPX2) serves as a promising prognostic marker and therapeutic target for gastric cancer., Liang B, Zheng W, Fang L, Wu L, Zhou F, Yin X, Yu X, Zou Z., Cancer Biol Ther. August 2, 2016; 17 (8): 824-32.

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1., Watson JR, Nietlispach D, Owen D, Mott HR., Biomol NMR Assign. October 1, 2016; 10 (2): 407-11.    

Evidence for Integrin - Venus Kinase Receptor 1 Alliance in the Ovary of Schistosoma mansoni Females Controlling Cell Survival., Gelmedin V, Morel M, Hahnel S, Cailliau K, Dissous C, Grevelding CG., PLoS Pathog. January 23, 2017; 13 (1): e1006147.                          

Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease., Stahl K, Rahmani S, Prydz A, Skauli N, MacAulay N, Mylonakou MN, Torp R, Skare Ø, Berg T, Leergaard TB, Paulsen RE, Ottersen OP, Amiry-Moghaddam M., PLoS One. January 1, 2018; 13 (3): e0194896.                

Developmental toxicity of dibutyl phthalate and citrate ester plasticizers in Xenopus laevis embryos., Xu Y, Xu Y, Gye MC., Chemosphere. August 1, 2018; 204 523-534.

Apoptosis propagates through the cytoplasm as trigger waves., Cheng X, Ferrell JE., Science. August 10, 2018; 361 (6402): 607-612.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z, Zheng B, Li J, Lv X, Zhang H, Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.          

Understanding MAPK Signaling Pathways in Apoptosis., Yue J, López JM., Int J Mol Sci. March 28, 2020; 21 (7):           

Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival., Sena E, Bou-Rouphael J, Rocques N, Carron-Homo C, Durand BC., Dev Dyn. July 1, 2020; 249 (7): 847-866.              

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