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Summary Expression Phenotypes Gene Literature (92) GO Terms (6) Nucleotides (107) Proteins (63) Interactants (644) Wiki
XB-GENEPAGE-486854

Papers associated with tbx5



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Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19., Yi CH, Terrett JA, Li QY, Ellington K, Packham EA, Armstrong-Buisseret L, McClure P, Slingsby T, Brook JD., Genomics. January 1, 1999; 55 (1): 10-20.

Tbx5 is essential for heart development., Horb ME, Thomsen GH., Development. April 1, 1999; 126 (8): 1739-51.              

Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus., Vaughan CJ, Basson CT., Am J Med Genet. January 1, 2000; 97 (4): 304-9.

Conserved and divergent expression of T-box genes Tbx2-Tbx5 in Xenopus., Takabatake Y, Takabatake T, Takeshima K., Mech Dev. March 1, 2000; 91 (1-2): 433-7.                            

Xbra3 induces mesoderm and neural tissue in Xenopus laevis., Strong CF, Barnett MW, Hartman D, Jones EA, Stott D., Dev Biol. June 15, 2000; 222 (2): 405-19.                  

Ventricular expression of tbx5 inhibits normal heart chamber development., Liberatore CM, Searcy-Schrick RD, Yutzey KE., Dev Biol. July 1, 2000; 223 (1): 169-80.

Wnt antagonism initiates cardiogenesis in Xenopus laevis., Schneider VA, Mercola M., Genes Dev. February 1, 2001; 15 (3): 304-15.        

A role for BMP signalling in heart looping morphogenesis in Xenopus., Breckenridge RA, Mohun TJ, Amaya E., Dev Biol. April 1, 2001; 232 (1): 191-203.          

Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation., Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, Komuro I., Nat Genet. July 1, 2001; 28 (3): 276-80.

Endoderm specification and differentiation in Xenopus embryos., Horb ME, Slack JM., Dev Biol. August 15, 2001; 236 (2): 330-43.                

Developmental paradigms in heart disease: insights from tinman., Prall OW, Elliott DA, Harvey RP., Ann Med. January 1, 2002; 34 (3): 148-56.

Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma., Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S., Development. February 1, 2002; 129 (3): 805-13.

Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome., Coll M, Seidman JG, Müller CW., Structure. March 1, 2002; 10 (3): 343-56.

Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA., Sasagawa S, Takabatake T, Takabatake Y, Muramatsu T, Takeshima K., Genesis. June 1, 2002; 33 (2): 86-96.                      

Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development., Takabatake Y, Takabatake T, Sasagawa S, Takeshima K., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.              

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5., Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D., Nature. July 24, 2003; 424 (6947): 443-7.

Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development., Ariizumi T, Kinoshita M, Yokota C, Takano K, Fukuda K, Moriyama N, Malacinski GM, Asashima M., Int J Dev Biol. September 1, 2003; 47 (6): 405-10.      

Transgenic analysis of the atrialnatriuretic factor (ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF., Small EM, Krieg PA., Dev Biol. September 1, 2003; 261 (1): 116-31.          

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart., Stennard FA, Costa MW, Elliott DA, Rankin S, Rankin S, Haast SJ, Lai D, McDonald LP, Niederreither K, Dolle P, Bruneau BG, Zorn AM, Harvey RP., Dev Biol. October 15, 2003; 262 (2): 206-24.  

Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies., Peng Y, Yang PH, Guo Y, Ng SS, Liu J, Fung PC, Tay D, Ge J, He ML, Kung HF, Lin MC., Invest Ophthalmol Vis Sci. January 1, 2004; 45 (1): 23-9.

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis., Brown DD, Martz SN, Binder O, Goetz SC, Price BM, Smith JC, Conlon FL., Development. February 1, 2005; 132 (3): 553-63.                

Myocardin is sufficient and necessary for cardiac gene expression in Xenopus., Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, Krieg PA., Development. March 1, 2005; 132 (5): 987-97.            

Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling., Lupo G, Liu Y, Qiu R, Chandraratna RA, Barsacchi G, He RQ, Harris WA., Development. April 1, 2005; 132 (7): 1737-48.                    

Nerve-dependent and -independent events in blastema formation during Xenopus froglet limb regeneration., Suzuki M, Satoh A, Ide H, Tamura K, Tamura K., Dev Biol. October 1, 2005; 286 (1): 361-75.              

Subdividing the embryo: a role for Notch signaling during germ layer patterning in Xenopus laevis., Contakos SP, Gaydos CM, Pfeil EC, McLaughlin KA., Dev Biol. December 1, 2005; 288 (1): 294-307.          

SOX7 and SOX18 are essential for cardiogenesis in Xenopus., Zhang C, Basta T, Klymkowsky MW., Dev Dyn. December 1, 2005; 234 (4): 878-91.                    

Xtbx6r, a novel T-box gene expressed in the paraxial mesoderm, has anterior neural-inducing activity., Yabe S, Tazumi S, Yokoyama J, Uchiyama H., Int J Dev Biol. January 1, 2006; 50 (8): 681-9.                        

Limb regeneration in Xenopus laevis froglet., Suzuki M, Suzuki M, Yakushiji N, Nakada Y, Satoh A, Ide H, Tamura K, Tamura K., ScientificWorldJournal. May 12, 2006; 6 Suppl 1 26-37.        

Developmental expression patterns of Tbx1, Tbx2, Tbx5, and Tbx20 in Xenopus tropicalis., Showell C, Christine KS, Mandel EM, Conlon FL., Dev Dyn. June 1, 2006; 235 (6): 1623-30.                      

TBX5 is required for embryonic cardiac cell cycle progression., Goetz SC, Brown DD, Conlon FL., Development. July 1, 2006; 133 (13): 2575-84.                

SALL4 is directly activated by TCF/LEF in the canonical Wnt signaling pathway., Böhm J, Sustmann C, Wilhelm C, Kohlhase J., Biochem Biophys Res Commun. September 29, 2006; 348 (3): 898-907.

Enhanced sensitivity and stability in two-color in situ hybridization by means of a novel chromagenic substrate combination., Hurtado R, Mikawa T., Dev Dyn. October 1, 2006; 235 (10): 2811-6.          

The Kruppel-like transcription factor KLF13 is a novel regulator of heart development., Lavallée G, Andelfinger G, Nadeau M, Lefebvre C, Nemer G, Horb ME, Nemer M., EMBO J. November 1, 2006; 25 (21): 5201-13.  

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        

Pan-myocardial expression of Cre recombinase throughout mouse development., Breckenridge R, Kotecha S, Towers N, Bennett M, Mohun T., Genesis. March 1, 2007; 45 (3): 135-44.

Constitutive over-expression of VEGF results in reduced expression of Hand-1 during cardiac development in Xenopus., Nagao K, Taniyama Y, Koibuchi N, Morishita R., Biochem Biophys Res Commun. August 3, 2007; 359 (3): 431-7.        

SHP-2 is required for the maintenance of cardiac progenitors., Langdon YG, Goetz SC, Berg AE, Swanik JT, Conlon FL., Development. November 1, 2007; 134 (22): 4119-30.    

Redundancy and evolution of GATA factor requirements in development of the myocardium., Peterkin T, Gibson A, Patient R., Dev Biol. November 15, 2007; 311 (2): 623-35.          

Lessons from the lily pad: Using Xenopus to understand heart disease., Bartlett HL, Weeks DL., Drug Discov Today Dis Models. January 1, 2008; 5 (3): 141-146.

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midline., Christine KS, Conlon FL., Dev Cell. April 1, 2008; 14 (4): 616-23.                                

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus., Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R., J Biol Chem. April 25, 2008; 283 (17): 11841-9.                        

XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage., Ito Y, Seno S, Nakamura H, Fukui A, Asashima M., Dev Biol. July 1, 2008; 319 (1): 34-45.                          

GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos., Haworth KE, Kotecha S, Mohun TJ, Latinkic BV., BMC Dev Biol. July 28, 2008; 8 74.                        

In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      

Coordinating the timing of cardiac precursor development during gastrulation: a new role for Notch signaling., Miazga CM, McLaughlin KA., Dev Biol. September 15, 2009; 333 (2): 285-96.            

Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis., Gessert S, Kühl M., Dev Biol. October 15, 2009; 334 (2): 395-408.          

Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling., Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.                

Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain., Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M., Mech Dev. January 1, 2010; 127 (1-2): 62-72.                

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