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Summary Expression Phenotypes Gene Literature (93) GO Terms (88) Nucleotides (107) Proteins (63) Interactants (669) Wiki
XB-GENEPAGE-486854

Papers associated with tbx5



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Deletion of sf3b4 causes splicing defects and gene dysregulation that disrupt craniofacial development and survival., Griffin C, Coppenrath K, Khan D, Lin Z, Horb M, Saint-Jeannet JP., Dis Model Mech. March 1, 2025; 18 (3):   


Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes., Neal SJ, Rajasekaran A, Jusić N, Taylor L, Read M, Alfandari D, Alfandari D, Pignoni F, Moody SA., J Exp Zool B Mol Dev Evol. May 1, 2024; 342 (3): 212-240.   


Expanding the CRISPR/Cas genome-editing scope in Xenopus tropicalis., Shi Z, Jiang H, Liu G, Shi S, Zhang X, Chen Y., Cell Biosci. July 8, 2022; 12 (1): 104.   


Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development., Rankin SA, Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM., Elife. October 13, 2021; 10


Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

RA Signaling in Limb Development and Regeneration in Different Species., Maden M., Subcell Biochem. January 1, 2020; 95 87-117.

Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia., Kariminejad A, Szenker-Ravi E, Lekszas C, Tajsharghi H, Moslemi AR, Naert T, Tran HT, Ahangari F, Rajaei M, Nasseri M, Haaf T, Azad A, Superti-Furga A, Maroofian R, Ghaderi-Sohi S, Najmabadi H, Abbaszadegan MR, Vleminckx K, Vleminckx K, Nikuei P, Reversade B., Am J Hum Genet. December 5, 2019; 105 (6): 1294-1301.   


The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M., Dev Biol. May 1, 2019; 449 (1): 1-13.   


Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development., Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T, Lee HS., Epigenetics Chromatin. December 6, 2018; 11 (1): 72.   


Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD, Rankin SA, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP., Proc Natl Acad Sci U S A. November 6, 2018; 115 (45): E10615-E10624.   


Tbx2 is required for the suppression of mesendoderm during early Xenopus development., Teegala S, Chauhan R, Lei E, Weinstein DC., Dev Dyn. July 1, 2018; 247 (7): 903-913.   


Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis., Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S., Dev Biol. February 1, 2018; 434 (1): 108-120.   


Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse., Chen Y, Xu H, Lin G., Cell Discov. December 19, 2017; 3 17046.   


Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.   


Thyroid Hormone Receptor α Controls Developmental Timing and Regulates the Rate and Coordination of Tissue-Specific Metamorphosis in Xenopus tropicalis., Wen L, Shibata Y, Su D, Fu L, Luu N, Shi YB, Shi YB., Endocrinology. June 1, 2017; 158 (6): 1985-1998.   


Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites., Liu CF, Brandt GS, Hoang QQ, Naumova N, Lazarevic V, Hwang ES, Dekker J, Glimcher LH, Ringe D, Petsko GA., Proc Natl Acad Sci U S A. October 25, 2016; 113 (43): E6572-E6581.   


Epigenetic modification maintains intrinsic limb-cell identity in Xenopus limb bud regeneration., Hayashi S, Kawaguchi A, Uchiyama I, Kawasumi-Kita A, Kobayashi T, Nishide H, Tsutsumi R, Tsuru K, Inoue T, Ogino H, Agata K, Tamura K, Yokoyama H., Dev Biol. October 15, 2015; 406 (2): 271-82.   


Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty., Grieb M, Burkovski A, Sträng JE, Kraus JM, Groß A, Palm G, Kühl M, Kestler HA., PLoS One. July 16, 2015; 10 (7): e0131832.   


Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity., Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A., Stem Cells. April 1, 2015; 33 (4): 1113-29.   


Dorsoventral patterning of the Xenopus eye involves differential temporal changes in the response of optic stalk and retinal progenitors to Hh signalling., Wang X, Lupo G, He R, Barsacchi G, Harris WA, Liu Y., Neural Dev. March 20, 2015; 10 7.   


COUP-TFs and eye development., Tang K, Tsai SY, Tsai MJ., Biochim Biophys Acta. February 1, 2015; 1849 (2): 201-9.   


Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4., Gallagher JM, Yamak A, Kirilenko P, Black S, Bochtler M, Lefebvre C, Nemer M, Latinkić BV., Mech Dev. November 1, 2014; 134 31-41.   


Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells., Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD., Stem Cells. June 1, 2014; 32 (6): 1515-26.   


Cyclin D2 is a GATA4 cofactor in cardiogenesis., Yamak A, Latinkic BV, Dali R, Temsah R, Nemer M., Proc Natl Acad Sci U S A. January 28, 2014; 111 (4): 1415-20.   


Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus., Shieh YE, Wells DE, Sater AK., Int J Dev Biol. January 1, 2014; 58 (1): 27-34.   


Tcf21 regulates the specification and maturation of proepicardial cells., Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL., Development. June 1, 2013; 140 (11): 2409-21.   


Islet1-expressing cardiac progenitor cells: a comparison across species., Pandur P, Sirbu IO, Kühl SJ, Philipp M, Kühl M., Dev Genes Evol. March 1, 2013; 223 (1-2): 117-29.   


Microarray-based identification of Pitx3 targets during Xenopus embryogenesis., Hooker L, Smoczer C, KhosrowShahian F, Wolanski M, Crawford MJ., Dev Dyn. September 1, 2012; 241 (9): 1487-505.   


Dissociation of cardiogenic and postnatal myocardial activities of GATA4., Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV., Mol Cell Biol. June 1, 2012; 32 (12): 2214-23.

SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y, Tandon P, Paden E, Duddy J, Taylor JM, Conlon FL., Development. March 1, 2012; 139 (5): 948-57.   


Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo., Martin LK, Bratoeva M, Mezentseva NV, Bernanke JM, Remond MC, Ramsdell AF, Eisenberg CA, Eisenberg LM., Dev Growth Differ. February 1, 2012; 54 (2): 153-66.   


Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos., Herrmann F, Bundschu K, Kühl SJ, Kühl M., Dev Dyn. December 1, 2011; 240 (12): 2634-45.   

Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation., Martin LK, Mezentseva NV, Bratoeva M, Ramsdell AF, Eisenberg CA, Eisenberg LM., Stem Cells Dev. November 1, 2011; 20 (11): 1973-83.

Cardiac neural crest is dispensable for outflow tract septation in Xenopus., Lee YH, Saint-Jeannet JP., Development. May 1, 2011; 138 (10): 2025-34.   


The secreted integrin ligand nephronectin is necessary for forelimb formation in Xenopus tropicalis., Abu-Daya A, Nishimoto S, Fairclough L, Mohun TJ, Logan MP, Zimmerman LB., Dev Biol. January 15, 2011; 349 (2): 204-12.   


Early cardiac morphogenesis defects caused by loss of embryonic macrophage function in Xenopus., Smith SJ, Mohun TJ., Mech Dev. January 1, 2011; 128 (5-6): 303-15.   


Different requirement for Wnt/β-catenin signaling in limb regeneration of larval and adult Xenopus., Yokoyama H, Maruoka T, Ochi H, Aruga A, Ohgo S, Ogino H, Tamura K, Tamura K., PLoS One. January 1, 2011; 6 (7): e21721.   


Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart., Puskaric S, Schmitteckert S, Mori AD, Glaser A, Schneider KU, Bruneau BG, Blaschke RJ, Steinbeisser H, Rappold G., Hum Mol Genet. December 1, 2010; 19 (23): 4625-33.   


Focal adhesion kinase is essential for cardiac looping and multichamber heart formation., Doherty JT, Conlon FL, Mack CP, Taylor JM., Genesis. August 1, 2010; 48 (8): 492-504.   


Oriented cell motility and division underlie early limb bud morphogenesis., Wyngaarden LA, Vogeli KM, Ciruna BG, Wells M, Hadjantonakis AK, Hopyan S., Development. August 1, 2010; 137 (15): 2551-8.   


The BMP pathway acts to directly regulate Tbx20 in the developing heart., Mandel EM, Kaltenbrun E, Callis TE, Zeng XX, Marques SR, Yelon D, Wang DZ, Conlon FL., Development. June 1, 2010; 137 (11): 1919-29.   


Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain., Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M., Mech Dev. January 1, 2010; 127 (1-2): 62-72.   


Zygotic VegT is required for Xenopus paraxial mesoderm formation and is regulated by Nodal signaling and Eomesodermin., Fukuda M, Takahashi S, Haramoto Y, Onuma Y, Kim YJ, Yeo CY, Ishiura S, Asashima M., Int J Dev Biol. January 1, 2010; 54 (1): 81-92.   


Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling., Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.   


Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis., Gessert S, Kühl M., Dev Biol. October 15, 2009; 334 (2): 395-408.   


Coordinating the timing of cardiac precursor development during gastrulation: a new role for Notch signaling., Miazga CM, McLaughlin KA., Dev Biol. September 15, 2009; 333 (2): 285-96.   


In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.   


GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos., Haworth KE, Kotecha S, Mohun TJ, Latinkic BV., BMC Dev Biol. July 28, 2008; 8 74.   


XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage., Ito Y, Seno S, Nakamura H, Fukui A, Asashima M., Dev Biol. July 1, 2008; 319 (1): 34-45.   

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