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Summary Expression Phenotypes Gene Literature (172) GO Terms (8) Nucleotides (126) Proteins (59) Interactants (895) Wiki
XB--487097

Papers associated with gsk3b



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Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3., Pierce SB, Kimelman D., Development. March 1, 1995; 121 (3): 755-65.              

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos., Dominguez I, Itoh K, Sokol SY., Proc Natl Acad Sci U S A. August 29, 1995; 92 (18): 8498-502.            

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B., Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA., Nature. December 1, 1995; 378 (6559): 785-9.

Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase., Itoh K, Tang TL, Neel BG, Sokol SY., Development. December 1, 1995; 121 (12): 3979-88.              

Regulation of dorsal-ventral axis formation in Xenopus by intercellular and intracellular signalling., Kimelman D, Pierce SB., Biochem Soc Symp. January 1, 1996; 62 13-23.

Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus., Pierce SB, Kimelman D., Dev Biol. May 1, 1996; 175 (2): 256-64.          

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development., Torres MA, Yang-Snyder JA, Purcell SM, DeMarais AA, McGrew LL, Moon RT., J Cell Biol. June 1, 1996; 133 (5): 1123-37.              

A molecular mechanism for the effect of lithium on development., Klein PS, Melton DA., Proc Natl Acad Sci U S A. August 6, 1996; 93 (16): 8455-9.

Analysis of Dishevelled signalling pathways during Xenopus development., Sokol SY., Curr Biol. November 1, 1996; 6 (11): 1456-67.                  

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action., Hedgepeth CM, Conrad LJ, Zhang J, Huang HC, Lee VM, Klein PS., Dev Biol. May 1, 1997; 185 (1): 82-91.          

Cell-cell signalling: frog frizbees., Zorn AM., Curr Biol. August 1, 1997; 7 (8): R501-4.      

Autonomous and nonautonomous regulation of axis formation by antagonistic signaling via 7-span cAMP receptors and GSK3 in Dictyostelium., Ginsburg GT, Kimmel AR., Genes Dev. August 15, 1997; 11 (16): 2112-23.

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta., Behrens J, Jerchow BA, Würtele M, Grimm J, Asbrand C, Wirtz R, Kühl M, Wedlich D, Birchmeier W., Science. April 24, 1998; 280 (5363): 596-9.

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin., Itoh K, Krupnik VE, Sokol SY., Curr Biol. May 7, 1998; 8 (10): 591-4.      

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta., Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P., Curr Biol. May 7, 1998; 8 (10): 573-81.

A role for Xenopus Frizzled 8 in dorsal development., Itoh K, Jacob J, Y Sokol S., Mech Dev. June 1, 1998; 74 (1-2): 145-57.  

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis., Yost C, Farr GH, Pierce SB, Ferkey DM, Chen MM, Kimelman D., Cell. June 12, 1998; 93 (6): 1031-41.

GSK3beta/shaggy mediates patterning along the animal-vegetal axis of the sea urchin embryo., Emily-Fenouil F, Ghiglione C, Lhomond G, Lepage T, Gache C., Development. July 1, 1998; 125 (13): 2489-98.

Nuclear glycogen and glycogen synthase kinase 3., Ragano-Caracciolo M, Berlin WK, Miller MW, Hanover JA., Biochem Biophys Res Commun. August 19, 1998; 249 (2): 422-7.

Properties of ectopic neurons induced by Xenopus neurogenin1 misexpression., Olson EC, Schinder AF, Dantzker JL, Marcus EA, Spitzer NC, Harris WA., Mol Cell Neurosci. November 1, 1998; 12 (4-5): 281-99.

The role of GSK3beta in regulating neuronal differentiation in Xenopus laevis., Marcus EA, Kintner C, Harris W., Mol Cell Neurosci. November 1, 1998; 12 (4-5): 269-80.

Negative regulation of axis formation and Wnt signaling in Xenopus embryos by the F-box/WD40 protein beta TrCP., Lagna G, Carnevali F, Marchioni M, Hemmati-Brivanlou A., Mech Dev. January 1, 1999; 80 (1): 101-6.        

Xenopus axin interacts with glycogen synthase kinase-3 beta and is expressed in the anterior midbrain., Hedgepeth CM, Deardorff MA, Klein PS., Mech Dev. February 1, 1999; 80 (2): 147-51.    

Regulation of ribosomal S6 protein kinase-p90(rsk), glycogen synthase kinase 3, and beta-catenin in early Xenopus development., Torres MA, Eldar-Finkelman H, Krebs EG, Moon RT., Mol Cell Biol. February 1, 1999; 19 (2): 1427-37.

Dishevelled: at the crossroads of divergent intracellular signaling pathways., Boutros M, Mlodzik M., Mech Dev. May 1, 1999; 83 (1-2): 27-37.  

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization., Fagotto F, Jho Eh, Zeng L, Kurth T, Joos T, Kaufmann C, Costantini F., J Cell Biol. May 17, 1999; 145 (4): 741-56.                  

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation., Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X., Proc Natl Acad Sci U S A. May 25, 1999; 96 (11): 6273-8.            

Establishment of the dorsal-ventral axis in Xenopus embryos coincides with the dorsal enrichment of dishevelled that is dependent on cortical rotation., Miller JR, Rowning BA, Larabell CA, Yang-Snyder JA, Bates RL, Moon RT., J Cell Biol. July 26, 1999; 146 (2): 427-37.                

Keeping a close eye on Wnt-1/wg signaling in Xenopus., Gradl D, Kühl M, Wedlich D., Mech Dev. August 1, 1999; 86 (1-2): 3-15.    

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin., Thomas GM, Frame S, Goedert M, Nathke I, Polakis P, Cohen P., FEBS Lett. September 17, 1999; 458 (2): 247-51.

Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development., Baker JC, Beddington RS, Harland RM., Genes Dev. December 1, 1999; 13 (23): 3149-59.              

New steps in the Wnt/beta-catenin signal transduction pathway., Sakanaka C, Sun TQ, Williams LT., Recent Prog Horm Res. January 1, 2000; 55 225-36.

The Yin-Yang of TCF/beta-catenin signaling., Barker N, Morin PJ, Clevers H., Adv Cancer Res. January 1, 2000; 77 1-24.

TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis., Vonica A, Weng W, Gumbiner BM, Venuti JM., Dev Biol. January 15, 2000; 217 (2): 230-43.

Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos., Dominguez I, Green JB., Development. February 1, 2000; 127 (4): 861-8.            

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification., Farr GH, Ferkey DM, Yost C, Pierce SB, Weaver C, Kimelman D., J Cell Biol. February 21, 2000; 148 (4): 691-702.      

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts., Salic A, Lee E, Lee E, Mayer L, Kirschner MW., Mol Cell. March 1, 2000; 5 (3): 523-32.

Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction., Itoh K, Antipova A, Ratcliffe MJ, Sokol S., Mol Cell Biol. March 1, 2000; 20 (6): 2228-38.

Primary neuronal differentiation in Xenopus embryos is linked to the beta(3) subunit of the sodium pump., Messenger NJ, Warner AE., Dev Biol. April 15, 2000; 220 (2): 168-82.                  

The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning., Sumanas S, Strege P, Heasman J, Ekker SC., Development. May 1, 2000; 127 (9): 1981-90.    

Control of beta-catenin signaling in tumor development., Behrens J., Ann N Y Acad Sci. June 1, 2000; 910 21-33; discussion 33-5.

Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C., Chen RH, Ding WV, McCormick F., J Biol Chem. June 9, 2000; 275 (23): 17894-9.

A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels., Guger KA, Gumbiner BM., Dev Biol. July 15, 2000; 223 (2): 441-8.

Xwnt11 and the regulation of gastrulation in Xenopus., Smith JC, Conlon FL, Saka Y, Tada M., Philos Trans R Soc Lond B Biol Sci. July 29, 2000; 355 (1399): 923-30.

GSK-3: new thoughts on an old enzyme., Ferkey DM, Kimelman D., Dev Biol. September 15, 2000; 225 (2): 471-9.

Glycogen synthase kinase 3beta negatively regulates both DNA-binding and transcriptional activities of heat shock factor 1., Xavier IJ, Mercier PA, McLoughlin CM, Ali A, Woodgett JR, Ovsenek N., J Biol Chem. September 15, 2000; 275 (37): 29147-52.

Effects of rat Axin domains on axis formation in Xenopus embryos., Fukui A, Kishida S, Kikuchi A, Asashima M., Dev Growth Differ. October 1, 2000; 42 (5): 489-98.

Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones., Shackleford GM, Ganguly A, MacArthur CA., BMC Genomics. January 1, 2001; 2 8.            

Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein., Hino S, Kishida S, Michiue T, Fukui A, Sakamoto I, Takada S, Asashima M, Kikuchi A., Mol Cell Biol. January 1, 2001; 21 (1): 330-42.

Wnt antagonism initiates cardiogenesis in Xenopus laevis., Schneider VA, Mercola M., Genes Dev. February 1, 2001; 15 (3): 304-15.        

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