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Summary Expression Phenotypes Gene Literature (128) GO Terms (15) Nucleotides (130) Proteins (52) Interactants (858) Wiki
XB--487158

Papers associated with hhex



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Cell landscape of larval and adult Xenopus laevis at single-cell resolution., Liao Y, Ma L, Guo Q, E W, Fang X, Yang L, Ruan F, Wang J, Zhang P, Sun Z, Chen H, Lin Z, Wang X, Wang X, Sun H, Fang X, Zhou Y, Chen M, Shen W, Guo G, Han X., Nat Commun. July 25, 2022; 13 (1): 4306.                                                        


Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):                         


Uncovering the mesendoderm gene regulatory network through multi-omic data integration., Jansen C, Paraiso KD, Zhou JJ, Blitz IL, Fish MB, Charney RM, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn AM, Mortazavi A, Cho KWY., Cell Rep. February 15, 2022; 38 (7): 110364.                            


Identification of ZBTB26 as a Novel Risk Factor for Congenital Hypothyroidism., Vick P, Eberle B, Choukair D, Weiss B, Roeth R, Schneider I, Paramasivam N, Bettendorf M, Rappold GA., Genes (Basel). November 24, 2021; 12 (12):                     


X-box-binding protein 1 is required for pancreatic development in Xenopus laevis., Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L., Acta Biochim Biophys Sin (Shanghai). December 11, 2020; 52 (11): 1215-1226.                  


Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY., Cell Rep. June 4, 2019; 27 (10): 2962-2977.e5.                          


Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Haworth K, Samuel L, Black S, Kirilenko P, Latinkic B., Front Physiol. January 1, 2019; 10 155.              


RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus., Griffin JN, Sondalle SB, Robson A, Mis EK, Griffin G, Kulkarni SS, Deniz E, Baserga SJ, Khokha MK., Development. October 18, 2018; 145 (20):                   


Katanin-like protein Katnal2 is required for ciliogenesis and brain development in Xenopus embryos., Willsey HR, Walentek P, Exner CRT, Xu Y, Xu Y, Lane AB, Harland RM, Heald R, Santama N., Dev Biol. October 15, 2018; 442 (2): 276-287.                                      


The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum., Womble M, Amin NM, Nascone-Yoder N., Dev Biol. July 15, 2018; 439 (2): 80-91.                  


Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis., Gere-Becker MB, Pommerenke C, Lingner T, Pieler T., Development. June 8, 2018; 145 (12):                                   


Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.          


A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo., Blitz IL, Paraiso KD, Patrushev I, Chiu WTY, Cho KWY, Gilchrist MJ., Dev Biol. June 15, 2017; 426 (2): 409-417.        


Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage., Kirmizitas A, Meiklejohn S, Ciau-Uitz A, Stephenson R, Patient R., Proc Natl Acad Sci U S A. June 6, 2017; 114 (23): 5814-5821.                    


A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs., Charney RM, Paraiso KD, Blitz IL, Cho KWY., Semin Cell Dev Biol. June 1, 2017; 66 12-24.    


Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition., Wagner G, Singhal N, Nicetto D, Straub T, Kremmer E, Rupp RAW., PLoS Genet. May 12, 2017; 13 (5): e1006757.                                    


Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        


An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs., Pearl E, Morrow S, Noble A, Lerebours A, Horb M, Guille M., Theriogenology. April 1, 2017; 92 149-155.        


Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.                            


Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit., Kepchia D, Moliver S, Chohan K, Phillips C, Luetje CW., PLoS One. January 1, 2017; 12 (5): e0177454.        


The histone methyltransferase Setd7 promotes pancreatic progenitor identity., Kofent J, Zhang J, Spagnoli FM., Development. October 1, 2016; 143 (19): 3573-3581.                        


Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development., Zhang Z, Zhang Z, Rankin SA, Rankin SA, Zorn AM., Dev Biol. August 1, 2016; 416 (1): 187-199.                                  


Xenopus as a Model for GI/Pancreas Disease., Salanga MC, Horb ME., Curr Pathobiol Rep. June 1, 2015; 3 (2): 137-145.


E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  


Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  


Recessive mutations in PCBD1 cause a new type of early-onset diabetes., Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K., Diabetes. October 1, 2014; 63 (10): 3557-64.


The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish., Young T, Poobalan Y, Tan EK, Tao S, Ong S, Wehner P, Schwenty-Lara J, Lim CY, Sadasivam A, Lovatt M, Wang ST, Ali Y, Borchers A, Sampath K, Dunn NR., Development. September 1, 2014; 141 (18): 3505-16.        


Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells., Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD., Stem Cells. June 1, 2014; 32 (6): 1515-26.              


Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements., Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ., PLoS One. February 19, 2014; 9 (2): e88385.        


Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis., Guo X, Zhang T, Hu Z, Zhang Y, Zhang Y, Shi Z, Wang Q, Cui Y, Wang F, Zhao H, Chen Y, Chen Y., Development. February 1, 2014; 141 (3): 707-14.              


Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns., Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho KW, Nie Q., BMC Syst Biol. January 8, 2014; 8 3.                  


Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation., Bavan S, Sherman B, Luetje CW, Abaffy T., PLoS One. January 1, 2014; 9 (3): e92064.            


Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence., Rodríguez-Seguel E, Mah N, Naumann H, Pongrac IM, Cerdá-Esteban N, Fontaine JF, Wang Y, Chen W, Andrade-Navarro MA, Spagnoli FM., Genes Dev. September 1, 2013; 27 (17): 1932-46.    


TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                


Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells., Zhang Z, Rankin SA, Zorn AM., Dev Biol. June 1, 2013; 378 (1): 1-12.                              


VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus., Ciau-Uitz A, Pinheiro P, Kirmizitas A, Zuo J, Patient R., Development. June 1, 2013; 140 (12): 2632-42.                                                                                                                            


Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut., Dush MK, Nascone-Yoder NM., Development. April 1, 2013; 140 (7): 1457-66.                      


Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus., Lim CY, Reversade B, Knowles BB, Solter D., Development. February 1, 2013; 140 (4): 853-60.                                              


β-hexosaminidase from Xenopus laevis eggs and oocytes: from gene to immunochemical characterization., Morales ES, Krapf D, Botta PE, Cabada MO, Arranz SE., J Cell Biochem. December 1, 2012; 113 (12): 3709-20.


Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.                      


Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling., Kenny AP, Rankin SA, Rankin SA, Allbee AW, Prewitt AR, Zhang Z, Tabangin ME, Shifley ET, Louza MP, Zorn AM., Dev Cell. August 14, 2012; 23 (2): 292-304.                                


Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos., Zhao H, Han D, Dawid IB, Pieler T, Chen Y, Chen Y., Proc Natl Acad Sci U S A. May 29, 2012; 109 (22): 8594-9.                              


Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells., Oropeza D, Horb M., Genesis. March 1, 2012; 50 (3): 271-85.                        


Xenopus staufen2 is required for anterior endodermal organ formation., Bilogan CK, Horb ME., Genesis. March 1, 2012; 50 (3): 251-9.                      


Ventx factors function as Nanog-like guardians of developmental potential in Xenopus., Scerbo P, Girardot F, Vivien C, Markov GV, Luxardi G, Demeneix B, Kodjabachian L, Coen L., PLoS One. January 1, 2012; 7 (5): e36855.              


Identification of new agonists and antagonists of the insect odorant receptor co-receptor subunit., Chen S, Luetje CW., PLoS One. January 1, 2012; 7 (5): e36784.          


A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            


Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes., Pearl EJ, Jarikji Z, Horb ME., Dev Biol. March 1, 2011; 351 (1): 135-45.                    


Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis., Wang JH, Deimling SJ, D'Alessandro NE, Zhao L, Possmayer F, Drysdale TA., BMC Dev Biol. January 26, 2011; 11 75.                            


Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo., Lim JW, Hummert P, Mills JC, Kroll KL., Development. January 1, 2011; 138 (1): 33-44.                    

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