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Summary Expression Phenotypes Gene Literature (522) GO Terms (40) Nucleotides (1106) Proteins (68) Interactants (2006) Wiki
XB--487199

Papers associated with ctnnb1 (and Disease Ontology)



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Molecular mechanisms of vertebrate left-right development., Ramsdell AF, Yost HJ., Trends Genet. November 1, 1998; 14 (11): 459-65.

The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition., Cruciat CM, Hassler C, Niehrs C., J Biol Chem. May 5, 2006; 281 (18): 12986-93.                        

The Wnt-dependent signaling pathways as target in oncology drug discovery., Janssens N, Janicot M, Perera T., Invest New Drugs. July 1, 2006; 24 (4): 263-80.        

Wnt/beta-catenin signaling: components, mechanisms, and diseases., MacDonald BT, Tamai K, He X., Dev Cell. July 1, 2009; 17 (1): 9-26.          

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α., Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM, Lee E., Nat Chem Biol. November 1, 2010; 6 (11): 829-36.

An essential role of the cysteine-rich domain of FZD4 in Norrin/Wnt signaling and familial exudative vitreoretinopathy., Zhang K, Harada Y, Wei X, Shukla D, Rajendran A, Tawansy K, Bedell M, Lim S, Shaw PX, He X, Yang Z., J Biol Chem. March 25, 2011; 286 (12): 10210-5.

FAK and WNT signaling: the meeting of two pathways in cancer and development., Fonar Y, Frank D., Anticancer Agents Med Chem. September 1, 2011; 11 (7): 600-6.

Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S, Cheng F, Liang J, Wu W, Zhang J., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA, Rankin SA, Gallas AL, Neto A, Gómez-Skarmeta JL, Zorn AM., Development. August 1, 2012; 139 (16): 3010-20.                                                                                

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A, Valensin S, Rossi M, Tunici P, Verani M, De Rosa A, Giordano C, Varrone M, Nencini A, Pratelli C, Benicchi T, Bakker A, Hill J, Sangthongpitag K, Pendharkar V, Liu B, Ng FM, Then SW, Jing Tai S, Cheong SM, He X, Caricasole A, Salerno M., Mol Cancer Ther. July 1, 2013; 12 (7): 1180-9.

The extreme anterior domain is an essential craniofacial organizer acting through Kinin-Kallikrein signaling., Jacox L, Sindelka R, Chen J, Rothman A, Dickinson A, Sive H., Cell Rep. July 24, 2014; 8 (2): 596-609.                            

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF, Predes D, Cerqueira DM, Reis AH, Amado NG, Cayres MC, Kuster RM, Oliveira FL, Mendes FA, Abreu JG., PLoS One. March 16, 2015; 10 (3): e0120919.              

NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo., Zhu X, Min Z, Tan R, Tao Q, Tao Q., Mech Dev. November 1, 2015; 138 Pt 3 305-12.                

ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia., Walentek P, Beyer T, Hagenlocher C, Müller C, Feistel K, Schweickert A, Harland RM, Blum M., Dev Biol. December 15, 2015; 408 (2): 292-304.                                

An oncologist׳s friend: How Xenopus contributes to cancer research., Hardwick LJ, Philpott A., Dev Biol. December 15, 2015; 408 (2): 180-7.  

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ, Xie SX, Chen YT, Xue JL, Zhang CJ, Zhu F., World J Gastroenterol. September 7, 2016; 22 (33): 7486-99.      

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M, Kanwal N, Dietmann P, Seigfried FA, Hempel A, Schütz D, Reim D, Engels R, Linnemann A, Schmeisser MJ, Bockmann J, Kühl M, Boeckers TM, Kühl SJ., Development. January 15, 2017; 144 (2): 321-333.                              

Leftward Flow Determines Laterality in Conjoined Twins., Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M., Curr Biol. February 20, 2017; 27 (4): 543-548.                

Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?, Gentzel M, Schambony A., Front Cell Dev Biol. May 26, 2017; 5 59.    

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

SATB1 downregulation induced by oxidative stress participates in trophoblast invasion by regulating β-catenin., Rao H, Bai Y, Li Q, Zhuang B, Yuan Y, Liu Y, Peng W, Baker PN, Tong C, Luo X, Qi H., Biol Reprod. June 1, 2018; 98 (6): 810-820.

Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate., Chuykin I, Ossipova O, Sokol SY., Elife. September 26, 2018; 7                                                           

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis., Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK., PLoS One. January 1, 2019; 14 (8): e0221698.                      

Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C., Dev Growth Differ. February 1, 2019; 61 (2): 186-197.                                

Modeling congenital kidney diseases in Xenopus laevis., Blackburn ATM, Miller RK., Dis Model Mech. April 9, 2019; 12 (4):       

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo., Bharathan NK, Dickinson AJG., Dev Biol. June 15, 2019; 450 (2): 115-131.                            

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Vleminckx K, Walentek P., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.                              

Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling., Duncan AR, González DP, Del Viso F, Robson A, Khokha MK, Griffin JN., Dev Biol. December 1, 2019; 456 (1): 1-7.        

Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects., Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK., J Clin Invest. February 3, 2020; 130 (2): 813-826.                                

The transcription factor Hypermethylated in Cancer 1 (Hic1) regulates neural crest migration via interaction with Wnt signaling., Ray H, Chang C., Dev Biol. July 15, 2020; 463 (2): 169-181.                

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Establishing embryonic territories in the context of Wnt signaling., Velloso I, Maia LA, Amado NG, Reis AH, He X, Abreu JG., Int J Dev Biol. January 1, 2021; 65 (4-5-6): 227-233.      

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

The RNA helicase DDX3 induces neural crest by promoting AKT activity., Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S., Development. January 19, 2021; 148 (2):                           

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P., Genesis. February 1, 2021; 59 (1-2): e23406.          

CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping., Naert T, Tulkens D, Van Nieuwenhuysen T, Przybyl J, Demuynck S, van de Rijn M, Al-Jazrawe M, Alman BA, Coucke PJ, De Leeneer K, Vanhove C, Savvides SN, Creytens D, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. November 23, 2021; 118 (47):                             

Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P., Cells Tissues Organs. January 1, 2022; 211 (6): 736-753.

A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5)., Shalomov B, Handklo-Jamal R, Reddy HP, Theodor N, Bera AK, Dascal N., J Physiol. March 1, 2022; 600 (6): 1419-1437.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A, Cousin H, Horr B, Alfandari D, Alfandari D., Front Cell Dev Biol. January 1, 2023; 11 1271178.                      

Mink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2., Colleluori V, Khokha MK., Dev Biol. March 1, 2023; 495 42-53.                            

Pleiotropy of autism-associated chromatin regulators., Lasser M, Sun N, Xu Y, Xu Y, Wang S, Drake S, Law K, Gonzalez S, Wang B, Drury V, Castillo O, Zaltsman Y, Dea J, Bader E, McCluskey KE, State MW, Willsey AJ, Willsey HR., Development. July 15, 2023; 150 (14):                   

TBC1D32 variants disrupt retinal ciliogenesis and cause retinitis pigmentosa., Bocquet B, Borday C, Erkilic N, Mamaeva D, Donval A, Masson C, Parain K, Kaminska K, Quinodoz M, Perea-Romero I, Garcia-Garcia G, Jimenez-Medina C, Boukhaddaoui H, Coget A, Leboucq N, Calzetti G, Gandolfi S, Percesepe A, Barili V, Uliana V, Delsante M, Bozzetti F, Scholl HP, Corton M, Ayuso C, Millan JM, Rivolta C, Meunier I, Perron M, Kalatzis V., JCI Insight. November 8, 2023; 8 (21):                                               

Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M, Yoon SM, Reet J, Chalkias A., Channels (Austin). December 1, 2024; 18 (1): 2297605.

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