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Summary Expression Phenotypes Gene Literature (210) GO Terms (13) Nucleotides (112) Proteins (49) Interactants (828) Wiki
XB--487801

Papers associated with cdkn1a



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Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation., Santoni M, Meneau F, Sekhsoukh N, Castella S, Le T, Miot M, Daldello EM., Cell Rep. February 27, 2024; 43 (2): 113782.                  

Overlapping action of T3 and T4 during Xenopus laevis development., Tribondeau A, Du Pasquier D, Benchouaia M, Blugeon C, Buisine N, Sachs LM., Front Endocrinol (Lausanne). January 1, 2024; 15 1360188.      

Metamorphic gene regulation programs in Xenopus tropicalis tadpole brain., Raj S, Sifuentes CJ, Kyono Y, Denver RJ., PLoS One. January 1, 2023; 18 (6): e0287858.                

Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment., Satou-Kobayashi Y, Kim JD, Fukamizu A, Asashima M., Sci Rep. July 15, 2021; 11 (1): 14537.          

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY, Zhou YM, Liao ZQ, Zhong JW, Liu YB, Zhao H, Liang CQ, Huang RJ, Park KS, Feng SS, Zheng L, Cai DQ, Qi XF., NPJ Regen Med. June 29, 2021; 6 (1): 36.                    

PAK1 Regulates MEC-17 Acetyltransferase Activity and Microtubule Acetylation during Proplatelet Extension., van Dijk J, Bompard G, Rabeharivelo G, Cau J, Delsert C, Morin N., Int J Mol Sci. October 13, 2020; 21 (20):


Developmentally-programmed cellular senescence is conserved and widespread in zebrafish., Da Silva-Álvarez S, Guerra-Varela J, Sobrido-Cameán D, Quelle A, Barreiro-Iglesias A, Sánchez L, Collado M., Aging (Albany NY). September 29, 2020; 12 (18): 17895-17901.      

The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy., Thawani A, Rale MJ, Coudray N, Bhabha G, Stone HA, Shaevitz JW, Petry S., Elife. June 15, 2020; 9                           

Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Feng C, Zhang HL, Zeng A, Bai M, Wang XJ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.            

TPX2 silencing exerts anti‑tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway., Huang DH, Jian J, Li S, Zhang Y, Liu LZ., Int J Mol Med. December 1, 2019; 44 (6): 2113-2122.          

HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer., Li F, Su M, Zhao H, Xie W, Cao S, Xu Y, Xu Y, Chen W, Wang L, Hou L, Tan W., Am J Transl Res. November 15, 2019; 11 (11): 7035-7048.

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance., Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refabért L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE., Am J Hum Genet. February 7, 2019; 104 (2): 229-245.                                  

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.          

Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development., Konjikusic MJ, Yeetong P, Boswell CW, Lee C, Lee C, Roberson EC, Ittiwut R, Suphapeetiporn K, Ciruna B, Gurnett CA, Wallingford JB, Shotelersuk V, Gray RS., PLoS Genet. November 6, 2018; 14 (11): e1007817.              

PDGF-A suppresses contact inhibition during directional collective cell migration., Nagel M, Winklbauer R., Development. July 5, 2018; 145 (13):                     

Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22., Zheng L, Suzuki H, Nakajo Y, Nakano A, Kato M., Cancer Sci. February 1, 2018; 109 (2): 395-402.

RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin., Aze A, Fragkos M, Bocquet S, Cau J, Méchali M., Nat Commun. December 14, 2017; 8 (1): 2130.            

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis., Whitworth GB, Misaghi BC, Rosenthal DM, Mills EA, Heinen DJ, Watson AH, Ives CW, Ali SH, Bezold K, Marsh-Armstrong N, Watson FL., Dev Biol. June 15, 2017; 426 (2): 360-373.              

Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish., Xiao C, Gao L, Hou Y, Xu C, Chang N, Wang F, Hu K, He A, Luo Y, Wang J, Peng J, Tang F, Zhu X, Xiong JW., Nat Commun. December 8, 2016; 7 13787.                

TPX2 promotes glioma cell proliferation and invasion via activation of the AKT signaling pathway., Gu JJ, Zhang JH, Chen HJ, Wang SS., Oncol Lett. December 1, 2016; 12 (6): 5015-5022.                

Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors., Ying G, Gerstner CD, Frederick JM, Boye SL, Hauswirth WW, Baehr W., PLoS One. August 16, 2016; 11 (8): e0161236.                  

CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart., Blech-Hermoni Y, Sullivan CB, Jenkins MW, Wessely O, Ladd AN., Dev Dyn. August 1, 2016; 245 (8): 854-73.                      

MutSα maintains the mismatch repair capability by inhibiting PCNA unloading., Kawasoe Y, Tsurimoto T, Nakagawa T, Masukata H, Takahashi TS., Elife. July 12, 2016; 5                                     

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination., He D, Marie C, Zhao C, Kim B, Wang J, Deng Y, Clavairoly A, Frah M, Wang H, He X, Hmidan H, Jones BV, Witte D, Zalc B, Zhou X, Choo DI, Martin DM, Parras C, Lu QR., Nat Neurosci. May 1, 2016; 19 (5): 678-89.            

YAP controls retinal stem cell DNA replication timing and genomic stability., Cabochette P, Vega-Lopez G, Bitard J, Parain K, Chemouny R, Masson C, Borday C, Hedderich M, Henningfeld KA, Locker M, Bronchain O, Perron M., Elife. September 22, 2015; 4 e08488.                                    

Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay., Lion M, Raimondi I, Donati S, Jousson O, Ciribilli Y, Inga A., PLoS One. February 10, 2015; 10 (2): e0116177.            

Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          

Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.              

EphA4-dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula., Evren S, Wen JW, Luu O, Damm EW, Nagel M, Winklbauer R., Development. October 1, 2014; 141 (19): 3649-61.                              

Thymine DNA glycosylase is a CRL4Cdt2 substrate., Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.

FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21(Waf1) and p27(Kip1)., Dombrowski C, Helledie T, Ling L, Grünert M, Canning CA, Jones CM, Hui JH, Nurcombe V, van Wijnen AJ, Cool SM., Stem Cells. December 1, 2013; 31 (12): 2724-36.

PCNA promotes processive DNA end resection by Exo1., Chen X, Paudyal SC, Chin RI, You Z., Nucleic Acids Res. November 1, 2013; 41 (20): 9325-38.              

Myb promotes centriole amplification and later steps of the multiciliogenesis program., Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA., Development. October 1, 2013; 140 (20): 4277-86.                

Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation., Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR, Yew PR., Cell Div. April 22, 2013; 8 (1): 5.              

PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth., Santiago-Medina M, Gregus KA, Gomez TM., J Cell Sci. March 1, 2013; 126 (Pt 5): 1122-33.

Spatial and temporal expressions of prune reveal a role in Müller gliogenesis during Xenopus retinal development., Bilitou A, De Marco N, Bello AM, Garzia L, Carotenuto P, Kim M, Campanella C, Ohnuma S, Zollo M., Gene. November 1, 2012; 509 (1): 93-103.                        

The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling., Jean S, Tremblay MG, Herdman C, Guillou F, Moss T., Biol Open. August 15, 2012; 1 (8): 731-8.          

The p21-activated kinase Pak1 regulates induction and migration of the neural crest in Xenopus., Bisson N, Wedlich D, Moss T., Cell Cycle. April 1, 2012; 11 (7): 1316-24.

Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2., Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC., J Biol Chem. March 30, 2012; 287 (14): 11410-21.

Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus., Park BY, Hong CS, Weaver JR, Rosocha EM, Saint-Jeannet JP., Dev Biol. February 1, 2012; 362 (1): 65-75.                

Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/RhoV., Shepelev MV, Korobko IV., Biochemistry (Mosc). January 1, 2012; 77 (1): 26-32.

Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations., Zimmermann I, Marabelli A, Bertozzi C, Sivilotti LG, Dutzler R., PLoS Biol. January 1, 2012; 10 (11): e1001429.              

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants., Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y, Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN., BMC Dev Biol. November 23, 2011; 11 71.                  

The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis., Shi YB, Hasebe T, Fu L, Fujimoto K, Ishizuya-Oka A., Cell Biosci. September 6, 2011; 1 (1): 30.        

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters., Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.              

Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase., Havens CG, Walter JC., Genes Dev. August 1, 2011; 25 (15): 1568-82.

VentX trans-activates p53 and p16ink4a to regulate cellular senescence., Wu X, Gao H, Ke W, Hager M, Xiao S, Freeman MR, Zhu Z., J Biol Chem. April 8, 2011; 286 (14): 12693-701.

Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis., Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H., Genes Cells. January 1, 2011; 16 (1): 12-22.        

Phosphoinositides are essential coactivators for p21-activated kinase 1., Strochlic TI, Viaud J, Rennefahrt UE, Anastassiadis T, Peterson JR., Mol Cell. November 12, 2010; 40 (3): 493-500.

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