Papers associated with nedd4l

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	Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l., Kim HS, Green YS, Xie Y, Christian JL., Proc Natl Acad Sci U S A. September 7, 2021; 118 (36):
	High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.
	Up-regulation of epithelial Na(+) channel ENaC by human parvovirus B19 capsid protein VP1., Ahmed M, Honisch S, Pelzl L, Fezai M, Hosseinzadeh Z, Bock CT, Kandolf R, Lang F., Biochem Biophys Res Commun. December 4, 2015; 468 (1-2): 179-84.
	USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2., Warsi J, Hosseinzadeh Z, Elvira B, Pelzl L, Shumilina E, Zhang DE, Lang KS, Lang PA, Lang F., PLoS One. June 5, 2015; 10 (6): e0129365.
	Chronic sublethal exposure to silver nanoparticles disrupts thyroid hormone signaling during Xenopus laevis metamorphosis., Carew AC, Hoque ME, Metcalfe CD, Peyrot C, Wilkinson KJ, Helbing CC., Aquat Toxicol. February 1, 2015; 159 99-108.
	PKC and AMPK regulation of Kv1.5 potassium channels., Andersen MN, Skibsbye L, Tang C, Petersen F, MacAulay N, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2015; 9 (3): 121-8.
	NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling., Zhang Y, Ding Y, Chen YG, Chen YG, Tao Q, Tao Q., Dev Biol. August 1, 2014; 392 (1): 15-25.
	WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter., Lagnaz D, Arroyo JP, Chávez-Canales M, Vázquez N, Rizzo F, Spirlí A, Debonneville A, Staub O, Gamba G., Am J Physiol Renal Physiol. August 1, 2014; 307 (3): F275-86.
	Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels., Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich DM, Bähring R, Bender RA., FASEB J. May 1, 2014; 28 (5): 2177-90.
	Down-regulation of the epithelial Na⁺ channel ENaC by Janus kinase 2., Hosseinzadeh Z, Luo D, Sopjani M, Bhavsar SK, Lang F., J Membr Biol. April 1, 2014; 247 (4): 331-8.
	Nedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons., Ekberg JA, Boase NA, Rychkov G, Manning J, Poronnik P, Kumar S, Kumar S., Biochem J. January 1, 2014; 457 (1): 27-31.
	AMP-activated protein kinase regulates hERG potassium channel., Almilaji A, Munoz C, Elvira B, Fajol A, Pakladok T, Honisch S, Shumilina E, Lang F, Föller M., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.
	Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8., L Y K, McIntosh CJ, Biasio W, Liu Y, Ke Y, Olson DR, Miller JH, Page R, Snyder PM, McDonald FJ., J Cell Physiol. November 1, 2013; 228 (11): 2190-201.
	WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination., Yu L, Cai H, Yue Q, Alli AA, Wang D, Al-Khalili O, Bao HF, Eaton DC., Am J Physiol Renal Physiol. July 1, 2013; 305 (1): F31-41.
	HECT domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting dishevelled for proteasomal degradation., Ding Y, Zhang Y, Zhang Y, Xu C, Tao QH, Chen YG, Chen YG., J Biol Chem. March 22, 2013; 288 (12): 8289-8298.
	Nedd4-2 does not regulate wt-CFTR in human airway epithelial cells., Koeppen K, Chapline C, Sato JD, Stanton BA., Am J Physiol Lung Cell Mol Physiol. October 15, 2012; 303 (8): L720-7.
	Protein kinase C (PKC)-promoted endocytosis of glutamate transporter GLT-1 requires ubiquitin ligase Nedd4-2-dependent ubiquitination but not phosphorylation., García-Tardón N, González-González IM, Martínez-Villarreal J, Fernández-Sánchez E, Giménez C, Zafra F., J Biol Chem. June 1, 2012; 287 (23): 19177-87.
	Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels., Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, Abriel H, Jespersen T., Heart Rhythm. March 1, 2012; 9 (3): 440-8.
	AMP-activated protein kinase downregulates Kv7.1 cell surface expression., Andersen MN, Krzystanek K, Jespersen T, Olesen SP, Rasmussen HB., Traffic. January 1, 2012; 13 (1): 143-56.
	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway., Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.
	Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2., Oberfeld B, Ruffieux-Daidié D, Vitagliano JJ, Pos KM, Verrey F, Staub O., Am J Physiol Renal Physiol. July 1, 2011; 301 (1): F189-96.
	Inhibition of Kir2.1 (KCNJ2) by the AMP-activated protein kinase., Alesutan I, Munoz C, Sopjani M, Dërmaku-Sopjani M, Michael D, Fraser S, Kemp BE, Seebohm G, Föller M, Lang F., Biochem Biophys Res Commun. May 20, 2011; 408 (4): 505-10.
	Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase., Alesutan I, Föller M, Sopjani M, Dërmaku-Sopjani M, Zelenak C, Fröhlich H, Velic A, Fraser S, Kemp BE, Seebohm G, Völkl H, Lang F., Mol Membr Biol. February 1, 2011; 28 (2): 79-89.
	AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells., Alzamora R, Gong F, Rondanino C, Lee JK, Smolak C, Pastor-Soler NM, Hallows KR., Am J Physiol Renal Physiol. December 1, 2010; 299 (6): F1308-19.
	Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2., Zhang W, Na T, Wu G, Jing H, Peng JB., J Biol Chem. November 19, 2010; 285 (47): 36586-96.
	Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel., Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D., J Biol Chem. July 9, 2010; 285 (28): 21671-8.
	COMMD1 downregulates the epithelial sodium channel through Nedd4-2., Ke Y, Butt AG, Swart M, Liu YF, McDonald FJ., Am J Physiol Renal Physiol. June 1, 2010; 298 (6): F1445-56.
	Human Nedd4L rs4149601 G allele generates evolutionary new isoform I with C2 domain., Ishigami T, Araki N, Umemura S., Hypertension. February 1, 2010; 55 (2): e10; author reply e11.
	Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species., Lazrak A, Iles KE, Liu G, Noah DL, Noah JW, Matalon S., FASEB J. November 1, 2009; 23 (11): 3829-42.
	A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain., Garrone NF, Blazer-Yost BL, Weiss RB, Lalouel JM, Rohrwasser A., BMC Cell Biol. April 13, 2009; 10 26.
	Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2., Edinger RS, Lebowitz J, Li H, Alzamora R, Wang H, Johnson JP, Hallows KR., J Biol Chem. January 2, 2009; 284 (1): 150-157.
	Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain., Bruce MC, Kanelis V, Fouladkou F, Debonneville A, Staub O, Rotin D., Biochem J. October 1, 2008; 415 (1): 155-63.
	Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1., Schuetz F, Kumar S, Poronnik P, Adams DJ., Am J Physiol Cell Physiol. July 1, 2008; 295 (1): C73-80.
	Regulation of the epithelial Na+ channel by the protein kinase CK2., Bachhuber T, Almaça J, Aldehni F, Mehta A, Amaral MD, Schreiber R, Kunzelmann K., J Biol Chem. May 9, 2008; 283 (19): 13225-32.
	Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1., Klaus F, Palmada M, Lindner R, Laufer J, Jeyaraj S, Lang F, Boehmer C., J Physiol. March 15, 2008; 586 (6): 1539-47.
	Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertension., Araki N, Umemura M, Miyagi Y, Yabana M, Miki Y, Tamura K, Tamura K, Tamura K, Uchino K, Aoki R, Goshima Y, Umemura S, Ishigami T., Hypertension. March 1, 2008; 51 (3): 773-7.
	NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity., Dibbens LM, Ekberg J, Taylor I, Hodgson BL, Conroy SJ, Lensink IL, Kumar S, Zielinski MA, Harkin LA, Sutherland GR, Adams DJ, Berkovic SF, Scheffer IE, Mulley JC, Poronnik P., Genes Brain Behav. November 1, 2007; 6 (8): 750-5.
	EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase., Rajamanickam J, Palmada M, Lang F, Boehmer C., J Neurochem. August 1, 2007; 102 (3): 858-66.
	Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2., Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ., J Biol Chem. April 20, 2007; 282 (16): 12135-42.
	Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation., Fakitsas P, Adam G, Daidié D, van Bemmelen MX, Fouladkou F, Patrignani A, Wagner U, Warth R, Camargo SM, Staub O, Verrey F., J Am Soc Nephrol. April 1, 2007; 18 (4): 1084-92.
	Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2., Hatanaka T, Hatanaka Y, Setou M., J Biol Chem. November 24, 2006; 281 (47): 35922-30.
	AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2., Bhalla V, Oyster NM, Fitch AC, Wijngaarden MA, Neumann D, Schlattner U, Pearce D, Hallows KR., J Biol Chem. September 8, 2006; 281 (36): 26159-69.
	14-3-3 Mediates phosphorylation-dependent inhibition of the interaction between the ubiquitin E3 ligase Nedd4-2 and epithelial Na+ channels., Nagaki K, Yamamura H, Shimada S, Saito T, Hisanaga S, Taoka M, Isobe T, Ichimura T., Biochemistry. May 30, 2006; 45 (21): 6733-40.
	Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases., Boehmer C, Palmada M, Rajamanickam J, Schniepp R, Amara S, Lang F., J Neurochem. May 1, 2006; 97 (4): 911-21.
	Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism., Michlig S, Harris M, Loffing J, Rossier BC, Firsov D., J Biol Chem. November 18, 2005; 280 (46): 38264-70.
	Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells., Flores SY, Loffing-Cueni D, Kamynina E, Daidié D, Gerbex C, Chabanel S, Dudler J, Loffing J, Staub O., J Am Soc Nephrol. August 1, 2005; 16 (8): 2279-87.
	Nedd4-2 isoforms differentially associate with ENaC and regulate its activity., Itani OA, Stokes JB, Thomas CP., Am J Physiol Renal Physiol. August 1, 2005; 289 (2): F334-46.
	Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits., Malik B, Yue Q, Yue G, Chen XJ, Price SR, Mitch WE, Eaton DC., Am J Physiol Renal Physiol. July 1, 2005; 289 (1): F107-16.
	14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase., Ichimura T, Yamamura H, Sasamoto K, Tominaga Y, Taoka M, Kakiuchi K, Shinkawa T, Takahashi N, Shimada S, Isobe T., J Biol Chem. April 1, 2005; 280 (13): 13187-94.
	Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells., Hryciw DH, Ekberg J, Lee A, Lensink IL, Kumar S, Guggino WB, Cook DI, Pollock CA, Poronnik P., J Biol Chem. December 31, 2004; 279 (53): 54996-5007.

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