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Summary Expression Phenotypes Gene Literature (31) GO Terms (3) Nucleotides (62) Proteins (39) Interactants (91) Wiki
XB--490480

Papers associated with gja5



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Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung., Hennemann H, Suchyna T, Lichtenberg-Fraté H, Jungbluth S, Dahl E, Schwarz J, Nicholson BJ, Willecke K., J Cell Biol. June 1, 1992; 117 (6): 1299-310.


Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins., Bruzzone R, Haefliger JA, Gimlich RL, Paul DL., Mol Biol Cell. January 1, 1993; 4 (1): 7-20.


Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease., Bruzzone R, White TW, Scherer SS, Fischbeck KH, Paul DL., Neuron. November 1, 1994; 13 (5): 1253-60.


Properties of gap junction channels formed of connexin 45 endogenously expressed in human hepatoma (SKHep1) cells., Moreno AP, Laing JG, Beyer EC, Spray DC., Am J Physiol. February 1, 1995; 268 (2 Pt 1): C356-65.


Functional analysis of selective interactions among rodent connexins., White TW, Paul DL, Goodenough DA, Bruzzone R., Mol Biol Cell. April 1, 1995; 6 (4): 459-70.


Expression of major gap junction connexin types in the working myocardium of eight chordates., Becker DL, Cook JE, Davies CS, Evans WH, Gourdie RG., Cell Biol Int. January 1, 1998; 22 (7-8): 527-43.


Connexin32 mutations associated with X-linked Charcot-Marie-Tooth disease show two distinct behaviors: loss of function and altered gating properties., Ressot C, Gomès D, Dautigny A, Pham-Dinh D, Bruzzone R., J Neurosci. June 1, 1998; 18 (11): 4063-75.


Identification of connexin43 as a functional target for Wnt signalling., van der Heyden MA, Rook MB, Hermans MM, Rijksen G, Boonstra J, Defize LH, Destrée OH., J Cell Sci. June 1, 1998; 111 ( Pt 12) 1741-9.


Biological functions of connexin genes revealed by human genetic defects, dominant negative approaches and targeted deletions in the mouse., Willecke K, Kirchhoff S, Plum A, Temme A, Thönnissen E, Ott T., Novartis Found Symp. January 1, 1999; 219 76-88; discussion 88-96.


Hetero-domain interactions as a mechanism for the regulation of connexin channels., Stergiopoulos K, Alvarado JL, Mastroianni M, Ek-Vitorin JF, Taffet SM, Delmar M., Circ Res. May 28, 1999; 84 (10): 1144-55.


UltraRapid communication : coexpression of connexins 40 and 43 enhances the pH sensitivityof gap junctions: A model for synergistic interactions among connexins, Gu H, Ek-Vitorin JF, Taffet SM, Delmar M., Circ Res. May 26, 2000; 86 (10): 1100.


Coexpression of connexins 40 and 43 enhances the pH sensitivity of gap junctions: a model for synergistic interactions among connexins., Gu H, Ek-Vitorin JF, Taffet SM, Delmar M., Circ Res. May 26, 2000; 86 (10): E98-E103.


The carboxyl terminal domain regulates the unitary conductance and voltage dependence of connexin40 gap junction channels., Anumonwo JM, Taffet SM, Gu H, Chanson M, Moreno AP, Delmar M., Circ Res. April 13, 2001; 88 (7): 666-73.


Early embryonic expression of ion channels and pumps in chick and Xenopus development., Rutenberg J, Cheng SM, Levin M., Dev Dyn. December 1, 2002; 225 (4): 469-84.                            


The voltage gates of connexin channels are sensitive to CO(2)., Peracchia C, Young KC, Wang XG, Chen JT, Peracchia LL., Cell Commun Adhes. January 1, 2003; 10 (4-6): 233-7.


A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill., Groenewegen WA, Firouzi M, Bezzina CR, Vliex S, van Langen IM, Sandkuijl L, Smits JP, Hulsbeek M, Rook MB, Jongsma HJ, Wilde AA., Circ Res. January 10, 2003; 92 (1): 14-22.


Opening hemichannels in nonjunctional membrane stimulates gap junction formation., Beahm DL, Hall JE., Biophys J. February 1, 2004; 86 (2): 781-96.


Gap junctions and the connexin protein family., Söhl G, Willecke K., Cardiovasc Res. May 1, 2004; 62 (2): 228-32.


CO(2) sensitivity of voltage gating and gating polarity of gapjunction channels--connexin40 and its COOH-terminus-truncated mutant., Peracchia C, Chen JT, Peracchia LL., J Membr Biol. July 15, 2004; 200 (2): 105-13.


The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities., Weber PA, Chang HC, Spaeth KE, Nitsche JM, Nicholson BJ., Biophys J. August 1, 2004; 87 (2): 958-73.


Interplay between cystic fibrosis transmembrane regulator and gap junction channels made of connexins 45, 40, 32 and 50 expressed in oocytes., Kotsias BA, Salim M, Peracchia LL, Peracchia C., J Membr Biol. January 1, 2006; 214 (1): 1-8.


Connexin31 cannot functionally replace connexin43 during cardiac morphogenesis in mice., Zheng-Fischhöfer Q, Ghanem A, Kim JS, Kibschull M, Schwarz G, Schwab JO, Nagy J, Winterhager E, Tiemann K, Willecke K., J Cell Sci. February 15, 2006; 119 (Pt 4): 693-701.


Connexin 40 promoter-based enrichment of embryonic stem cell-derived cardiovascular progenitor cells., David R, Theiss H, Franz WM., Cells Tissues Organs. January 1, 2008; 188 (1-2): 62-9.


Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5., Espinoza-Lewis RA, Yu L, He F, Liu H, Tang R, Shi J, Sun X, Martin JF, Wang D, Yang J, Chen Y., Dev Biol. March 15, 2009; 327 (2): 376-85.      


Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains., Bouvier D, Spagnol G, Chenavas S, Kieken F, Vitrac H, Brownell S, Kellezi A, Forge V, Sorgen PL., J Biol Chem. December 4, 2009; 284 (49): 34257-71.


Multiple loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome., Gui J, Wang T, Jones RP, Trump D, Zimmer T, Lei M., PLoS One. June 7, 2010; 5 (6): e10985.              


Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue., Thibodeau IL, Xu J, Li Q, Liu G, Lam K, Veinot JP, Birnie DH, Jones DL, Krahn AD, Lemery R, Nicholson BJ, Gollob MH., Circulation. July 20, 2010; 122 (3): 236-44.


Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling., Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O., Dev Cell. April 19, 2011; 20 (4): 526-39.  


Identifying the evolutionary building blocks of the cardiac conduction system., Jensen B, Boukens BJ, Postma AV, Gunst QD, van den Hoff MJ, Moorman AF, Wang T, Christoffels VM., PLoS One. January 1, 2012; 7 (9): e44231.                    


Voltage-dependent conformational changes in connexin channels., Bargiello TA, Tang Q, Oh S, Kwon T., Biochim Biophys Acta. August 1, 2012; 1818 (8): 1807-22.


Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice., Morton SK, Chaston DJ, Howitt L, Heisler J, Nicholson BJ, Fairweather S, Bröer S, Ashton AW, Matthaei KI, Hill CE., Hypertension. March 1, 2015; 65 (3): 662-9.

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