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Summary Expression Gene Literature (46) GO Terms (12) Nucleotides (54) Proteins (28) Interactants (45) Wiki

Papers associated with kcnj4

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Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference., Koepple C, Scherer D, Seyler C, Scholz E, Thomas D, Katus HA, Zitron E., J Pharmacol Exp Ther. January 1, 2017; 361 (2): 209-218.

The WD40 Domain of HIRA Is Essential for RI-nucleosome Assembly in Xenopus Egg Extracts., Zhu R, Iwabuchi M, Ohsumi K., Cell Struct Funct. January 1, 2017; 42 (1): 37-48.

Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224., Xynogalos P, Seyler C, Scherer D, Koepple C, Scholz EP, Thomas D, Katus HA, Zitron E., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2014; 387 (12): 1153-61.

P639Amiodarone and dronedarone inhibit inwardly rectifying Kir2.1 channels, but not Kir2.2 and Kir2.3 channels., Seyler C, Xynogalos P, Scherer D, Koepple C, Scholz E, Thomas D, Katus H, Zitron E., Cardiovasc Res. July 15, 2014; 103 Suppl 1 S116.

Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype., Limberg MM, Zumhagen S, Netter MF, Coffey AJ, Grace A, Rogers J, Böckelmann D, Rinné S, Stallmeyer B, Decher N, Schulze-Bahr E., Basic Res Cardiol. May 1, 2013; 108 (3): 353.

Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A., Kulzer M, Seyler C, Welke F, Scherer D, Xynogalos P, Scholz EP, Thomas D, Becker R, Karle CA, Katus HA, Zitron E., Biochem Biophys Res Commun. July 27, 2012; 424 (2): 315-20.

Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1., Raphemot R, Lonergan DF, Nguyen TT, Utley T, Lewis LM, Kadakia R, Weaver CD, Gogliotti R, Hopkins C, Lindsley CW, Denton JS., Front Pharmacol. January 1, 2011; 2 75.              

Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3., Kobayashi T, Washiyama K, Ikeda K., PLoS One. July 21, 2009; 4 (7): e6311.              

Molecular basis for genistein-induced inhibition of Kir2.3 currents., Zhao Z, Liu B, Zhang G, Jia Z, Jia Q, Geng X, Zhang H., Pflugers Arch. May 1, 2008; 456 (2): 413-23.

Arachidonic acid activates Kir2.3 channels by enhancing channel-phosphatidyl-inositol 4,5-bisphosphate interactions., Wang C, Mirshahi UL, Liu B, Jia Z, Mirshahi T, Zhang H., Mol Pharmacol. April 1, 2008; 73 (4): 1185-94.

AP-2-dependent internalization of potassium channel Kir2.3 is driven by a novel di-hydrophobic signal., Mason AK, Jacobs BE, Welling PA., J Biol Chem. March 7, 2008; 283 (10): 5973-84.

Kir2.x inward rectifier potassium channels are differentially regulated by adrenergic alpha1A receptors., Zitron E, Günth M, Scherer D, Kiesecker C, Kulzer M, Bloehs R, Scholz EP, Thomas D, Weidenhammer C, Kathöfer S, Bauer A, Katus HA, Karle CA., J Mol Cell Cardiol. January 1, 2008; 44 (1): 84-94.

Novel insights into the structural basis of pH-sensitivity in inward rectifier K+ channels Kir2.3., Ureche ON, Baltaev R, Ureche L, Strutz-Seebohm N, Lang F, Seebohm G., Cell Physiol Biochem. January 1, 2008; 21 (5-6): 347-56.

Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells., Muñoz V, Vaidyanathan R, Tolkacheva EG, Dhamoon AS, Taffet SM, Anumonwo JM., Heart Rhythm. April 1, 2007; 4 (4): 487-96.

Selective inhibition of Kir currents by antihistamines., Liu B, Jia Z, Geng X, Bei J, Zhao Z, Jia Q, Zhang H., Eur J Pharmacol. March 8, 2007; 558 (1-3): 21-6.

Identification of two functional estrogen response elements complexed with AP-1-like sites in the human insulin receptor gene promoter., García-Arencibia M, Dávila N, Campión J, Carmen Carranza M, Calle C., J Steroid Biochem Mol Biol. February 1, 2005; 94 (1-3): 1-14.

Expression and coexpression of CO2-sensitive Kir channels in brainstem neurons of rats., Wu J, Xu H, Shen W, Jiang C., J Membr Biol. February 1, 2004; 197 (3): 179-91.

Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen''s syndrome., Preisig-Müller R, Schlichthörl G, Goerge T, Heinen S, Brüggemann A, Rajan S, Derst C, Veh RW, Daut J., Proc Natl Acad Sci U S A. May 28, 2002; 99 (11): 7774-9.

Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes., Liu GX, Derst C, Schlichthörl G, Heinen S, Seebohm G, Brüggemann A, Kummer W, Veh RW, Daut J, Preisig-Müller R., J Physiol. April 1, 2001; 532 (Pt 1): 115-26.

Gating of inward rectifier K+ channels by proton-mediated interactions of N- and C-terminal domains., Qu Z, Yang Z, Cui N, Zhu G, Liu C, Xu H, Chanchevalap S, Shen W, Wu J, Li Y, Jiang C., J Biol Chem. October 13, 2000; 275 (41): 31573-80.

CO(2) inhibits specific inward rectifier K(+) channels by decreases in intra- and extracellular pH., Zhu G, Liu C, Qu Z, Chanchevalap S, Xu H, Jiang C., J Cell Physiol. April 1, 2000; 183 (1): 53-64.

The effects of oxidizing and cysteine-reactive reagents on the inward rectifier potassium channels Kir2.3 and Kir1.1., Bannister JP, Young BA, Main MJ, Sivaprasadarao A, Wray D., Pflugers Arch. November 1, 1999; 438 (6): 868-78.

Conserved extracellular cysteine residues in the inwardly rectifying potassium channel Kir2.3 are required for function but not expression in the membrane., Bannister JP, Young BA, Sivaprasadarao A, Wray D., FEBS Lett. September 24, 1999; 458 (3): 393-9.

Identification of a critical motif responsible for gating of Kir2.3 channel by intracellular protons., Qu Z, Zhu G, Yang Z, Cui N, Li Y, Chanchevalap S, Sulaiman S, Haynie H, Jiang C., J Biol Chem. May 14, 1999; 274 (20): 13783-9.

Effects of intra- and extracellular acidifications on single channel Kir2.3 currents., Zhu G, Chanchevalap S, Cui N, Jiang C., J Physiol. May 1, 1999; 516 ( Pt 3) 699-710.

Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53., Zhu G, Qu Z, Cui N, Jiang C., J Biol Chem. April 23, 1999; 274 (17): 11643-6.

Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells., Bradley KK, Jaggar JH, Bonev AD, Heppner TJ, Flynn ER, Nelson MT, Horowitz B., J Physiol. March 15, 1999; 515 ( Pt 3) 639-51.

A novel crystallization method for visualizing the membrane localization of potassium channels., Lopatin AN, Makhina EN, Nichols CG., Biophys J. May 1, 1998; 74 (5): 2159-70.

Basolateral membrane targeting of a renal-epithelial inwardly rectifying potassium channel from the cortical collecting duct, CCD-IRK3, in MDCK cells., Le Maout S, Brejon M, Olsen O, Merot J, Welling PA., Proc Natl Acad Sci U S A. November 25, 1997; 94 (24): 13329-34.

Regulation of IRK3 inward rectifier K+ channel by m1 acetylcholine receptor and intracellular magnesium., Chuang H, Jan YN, Jan LY., Cell. June 27, 1997; 89 (7): 1121-32.

Primary structure and functional expression of a cortical collecting duct Kir channel., Welling PA., Am J Physiol. January 1, 1997; 273 (5): F825-36.

Inhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunits., Cohen NA, Sha Q, Makhina EN, Lopatin AN, Linder ME, Snyder SH, Nichols CG., J Biol Chem. December 13, 1996; 271 (50): 32301-5.

Molecular and functional heterogeneity of inward rectifier potassium channels in brain and heart., Kurachi Y, Takahashi N., J Card Fail. December 1, 1996; 2 (4 Suppl): S59-62.

Depletion of intracellular polyamines relieves inward rectification of potassium channels., Shyng SL, Sha Q, Ferrigni T, Lopatin AN, Nichols CG., Proc Natl Acad Sci U S A. October 15, 1996; 93 (21): 12014-9.

Protein kinase C inhibition of cloned inward rectifier (HRK1/KIR2.3) K+ channels expressed in Xenopus oocytes., Henry P, Pearson WL, Nichols CG., J Physiol. September 15, 1996; 495 ( Pt 3) 681-8.

Spermidine release from xenopus oocytes. Electrodiffusion through a membrane channel., Sha Q, Romano C, Lopatin AN, Nichols CG., J Biol Chem. February 16, 1996; 271 (7): 3392-7.

Dominant negative chimeras provide evidence for homo and heteromultimeric assembly of inward rectifier K+ channel proteins via their N-terminal end., Fink M, Duprat F, Heurteaux C, Lesage F, Romey G, Barhanin J, Lazdunski M., FEBS Lett. January 2, 1996; 378 (1): 64-8.

A strongly inwardly rectifying K+ channel that is sensitive to ATP., Collins A, German MS, Jan YN, Jan LY, Zhao B., J Neurosci. January 1, 1996; 16 (1): 1-9.

Susceptibility of cloned K+ channels to reactive oxygen species., Duprat F, Guillemare E, Romey G, Fink M, Lesage F, Lazdunski M, Honore E., Proc Natl Acad Sci U S A. December 5, 1995; 92 (25): 11796-800.

The mechanism of inward rectification of potassium channels: "long-pore plugging" by cytoplasmic polyamines., Lopatin AN, Makhina EN, Nichols CG., J Gen Physiol. November 1, 1995; 106 (5): 923-55.

Identification and molecular localization of a pH-sensing domain for the inward rectifier potassium channel HIR., Coulter KL, Périer F, Radeke CM, Vandenberg CA., Neuron. November 1, 1995; 15 (5): 1157-68.

Cloning, localization, and functional expression of a human brain inward rectifier potassium channel (hIRK1)., Tang W, Qin CL, Yang XC., Recept Channels. January 1, 1995; 3 (3): 175-83.

Cloning and expression of a novel human brain inward rectifier potassium channel., Makhina EN, Kelly AJ, Lopatin AN, Mercer RW, Nichols CG., J Biol Chem. August 12, 1994; 269 (32): 20468-74.

Cloning a novel human brain inward rectifier potassium channel and its functional expression in Xenopus oocytes., Tang W, Yang XC., FEBS Lett. July 18, 1994; 348 (3): 239-43.

Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus., Périer F, Radeke CM, Vandenberg CA., Proc Natl Acad Sci U S A. June 21, 1994; 91 (13): 6240-4.

Molecular cloning and functional expression of a novel brain-specific inward rectifier potassium channel., Morishige K, Takahashi N, Jahangir A, Yamada M, Koyama H, Zanelli JS, Kurachi Y., FEBS Lett. June 13, 1994; 346 (2-3): 251-6.

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