Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (54) GO Terms (20) Nucleotides (108) Proteins (45) Interactants (230) Wiki
XB-GENEPAGE-5775580

Papers associated with has2



???displayGene.coCitedPapers???
6 ???displayGene.morpholinoPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

referenced by:


Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm., Luu O, Barua D, Winklbauer R., PLoS One. January 1, 2024; 19 (2): e0297420.                  


Cell-cell contact landscapes in Xenopus gastrula tissues., Barua D, Nagel M, Winklbauer R., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                           


CPEB3 regulates the proliferation and apoptosis of bovine cumulus cells., Wang Y, Chen CZ, Fu XH, Liu JB, Peng YX, Wang YJ, Han DX, Zhang Z, Yuan B, Gao Y, Jiang H, Zhang JB., Anim Sci J. January 1, 2020; 91 (1): e13416.


Expression of hyaluronan synthases upregulated by thyroid hormone is involved in intestinal stem cell development during Xenopus laevis metamorphosis., Fujimoto K, Hasebe T, Kajita M, Ishizuya-Oka A., Dev Genes Evol. December 1, 2018; 228 (6): 267-273.


Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice., Guzeloglu-Kayisli O, Lalioti MD, Aydiner F, Sasson I, Ilbay O, Sakkas D, Lowther KM, Mehlmann LM, Seli E., Biochem J. August 15, 2012; 446 (1): 47-58.


Hyaluronan is required for cranial neural crest cells migration and craniofacial development., Casini P, Nardi I, Ori M., Dev Dyn. February 1, 2012; 241 (2): 294-302.              


Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway., Luxardi G, Marchal L, Thomé V, Kodjabachian L., Development. February 1, 2010; 137 (3): 417-26.          


Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles., Contreras EG, Gaete M, Sánchez N, Carrasco H, Larraín J., Development. September 1, 2009; 136 (17): 2987-96.                    


In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      


XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage., Ito Y, Seno S, Nakamura H, Fukui A, Asashima M., Dev Biol. July 1, 2008; 319 (1): 34-45.                          


XHas2 activity is required during somitogenesis and precursor cell migration in Xenopus development., Ori M, Nardini M, Casini P, Perris R, Nardi I., Development. February 1, 2006; 133 (4): 631-40.                        


Microarray-based identification of VegT targets in Xenopus., Taverner NV, Kofron M, Kofron M, Shin Y, Kabitschke C, Gilchrist MJ, Wylie C, Cho KW, Heasman J, Smith JC., Mech Dev. March 1, 2005; 122 (3): 333-54.                                          


Regulated gene expression of hyaluronan synthases during Xenopus laevis development., Nardini M, Ori M, Vigetti D, Gornati R, Nardi I, Perris R., Gene Expr Patterns. May 1, 2004; 4 (3): 303-8.        


Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation., Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M., Development. February 1, 2004; 131 (3): 525-37.


Effects of TGF-beta on hyaluronan anabolism in fibroblasts derived from the synovial membrane of the rabbit temporomandibular joint., Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Yoneno K, Ohno-Nakahara M, Nakatani Y, Ueki M, Tanne K., J Dent Res. January 1, 2004; 83 (1): 40-4.


Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3., Karvinen S, Pasonen-Seppänen S, Hyttinen JM, Pienimäki JP, Törrönen K, Jokela TA, Tammi MI, Tammi R., J Biol Chem. December 5, 2003; 278 (49): 49495-504.


Molecular cloning, genomic organization and developmental expression of the Xenopus laevis hyaluronan synthase 3., Vigetti D, Viola M, Gornati R, Ori M, Nardi I, Passi A, De Luca G, Bernardini G., Matrix Biol. November 1, 2003; 22 (6): 511-7.  


The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers., Monslow J, Williams JD, Norton N, Guy CA, Price IK, Coleman SL, Williams NM, Buckland PR, Spicer AP, Topley N, Davies M, Bowen T., Int J Biochem Cell Biol. August 1, 2003; 35 (8): 1272-83.


Expression of hyaluronan synthases and corresponding hyaluronan receptors is differentially regulated during oocyte maturation in cattle., Schoenfelder M, Einspanier R., Biol Reprod. July 1, 2003; 69 (1): 269-77.


Abnormal expression of hyaluronan synthases in patients with Waldenstrom's macroglobulimenia., Adamia S, Crainie M, Kriangkum J, Mant MJ, Belch AR, Pilarski LM., Semin Oncol. April 1, 2003; 30 (2): 165-8.


Hyaluronan synthase in trabecular meshwork cells., Usui T, Nakajima F, Ideta R, Kaji Y, Suzuki Y, Araie M, Miyauchi S, Heldin P, Yamashita H., Br J Ophthalmol. March 1, 2003; 87 (3): 357-60.


Expression of hyaluronan synthase in intraocular proliferative diseases: regulation of expression in human vascular endothelial cells by transforming growth factor-beta., Suzuki K, Yamamoto T, Usui T, Suzuki K, Heldin P, Yamashita H., Jpn J Ophthalmol. January 1, 2003; 47 (6): 557-64.


Mammalian hyaluronan synthases., Itano N, Kimata K., IUBMB Life. October 1, 2002; 54 (4): 195-9.


Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients., Calabro A, Oken MM, Hascall VC, Masellis AM., Blood. October 1, 2002; 100 (7): 2578-85.


Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells., Simpson MA, Wilson CM, Furcht LT, Spicer AP, Oegema TR, McCarthy JB., J Biol Chem. March 22, 2002; 277 (12): 10050-7.


Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration., Itano N, Atsumi F, Sawai T, Yamada Y, Miyaishi O, Senga T, Hamaguchi M, Kimata K., Proc Natl Acad Sci U S A. March 19, 2002; 99 (6): 3609-14.


Expression of hyaluronan synthases and CD44 messenger RNAs in porcine cumulus-oocyte complexes during in vitro maturation., Kimura N, Konno Y, Miyoshi K, Matsumoto H, Sato E., Biol Reprod. March 1, 2002; 66 (3): 707-17.


Platelet-derived growth factor stimulates the formation of versican-hyaluronan aggregates and pericellular matrix expansion in arterial smooth muscle cells., Evanko SP, Johnson PY, Braun KR, Underhill CB, Dudhia J, Wight TN., Arch Biochem Biophys. October 1, 2001; 394 (1): 29-38.


Regulation of hyaluronan synthase gene expression in human periodontal ligament cells by tumour necrosis factor-alpha, interleukin-1beta and interferon-gamma., Ijuin C, Ohno S, Tanimoto K, Honda K, Tanne K., Arch Oral Biol. August 1, 2001; 46 (8): 767-72.


Molecular cloning of rabbit hyaluronic acid synthases and their expression patterns in synovial membrane and articular cartilage., Ohno S, Tanimoto K, Fujimoto K, Ijuin C, Honda K, Tanaka N, Doi T, Nakahara M, Tanne K., Biochim Biophys Acta. July 30, 2001; 1520 (1): 71-8.


Reticular erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes., Tominaga A, Tajima S, Ishibashi A, Kimata K., Br J Dermatol. July 1, 2001; 145 (1): 141-5.


Up-regulation of putative hyaluronan synthase mRNA by basic fibroblast growth factor and insulin-like growth factor-1 in human skin fibroblasts., Kuroda K, Utani A, Hamasaki Y, Shinkai H., J Dermatol Sci. June 1, 2001; 26 (2): 156-60.


Hyaluronan synthase elevation in metastatic prostate carcinoma cells correlates with hyaluronan surface retention, a prerequisite for rapid adhesion to bone marrow endothelial cells., Simpson MA, Reiland J, Burger SR, Furcht LT, Spicer AP, Oegema TR, McCarthy JB., J Biol Chem. May 25, 2001; 276 (21): 17949-57.


Regulation of renal proximal tubular epithelial cell hyaluronan generation: implications for diabetic nephropathy., Jones S, Jones S, Phillips AO., Kidney Int. May 1, 2001; 59 (5): 1739-49.


Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells., Recklies AD, White C, Melching L, Roughley PJ., Biochem J. February 15, 2001; 354 (Pt 1): 17-24.


Proinflammatory cytokines regulate the gene expression of hyaluronic acid synthetase in cultured rabbit synovial membrane cells., Tanimoto K, Ohno S, Fujimoto K, Honda K, Ijuin C, Tanaka N, Doi T, Nakahara M, Tanne K., Connect Tissue Res. January 1, 2001; 42 (3): 187-95.


Expression regulation of hyaluronan synthase in corneal endothelial cells., Usui T, Amano S, Oshika T, Suzuki K, Miyata K, Araie M, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. October 1, 2000; 41 (11): 3261-7.


Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: a molecular mechanism contributing to organ atrophy., Zhang W, Watson CE, Liu C, Williams KJ, Werth VP., Biochem J. July 1, 2000; 349 (Pt 1): 91-7.


Expression of human hyaluronan synthases in response to external stimuli., Jacobson A, Brinck J, Briskin MJ, Spicer AP, Heldin P., Biochem J. May 15, 2000; 348 Pt 1 29-35.


Synthesis of hyaluronan of distinctly different chain length is regulated by differential expression of Xhas1 and 2 during early development of Xenopus laevis., Köprunner M, Müllegger1 J, Lepperdinger G., Mech Dev. February 1, 2000; 90 (2): 275-8.


The effect of mechanical strain on hyaluronan metabolism in embryonic fibrocartilage cells., Dowthwaite GP, Ward AC, Flannely J, Suswillo RF, Flannery CR, Archer CW, Pitsillides AA., Matrix Biol. December 1, 1999; 18 (6): 523-32.


Increased synthesis of hyaluronate enhances motility of human melanoma cells., Ichikawa T, Itano N, Sawai T, Kimata K, Koganehira Y, Saida T, Taniguchi S., J Invest Dermatol. December 1, 1999; 113 (6): 935-9.


Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy., Kaback LA, Smith TJ., J Clin Endocrinol Metab. November 1, 1999; 84 (11): 4079-84.


Expression of recombinant hyaluronan synthase (HAS) isoforms in CHO cells reduces cell migration and cell surface CD44., Brinck J, Heldin P., Exp Cell Res. November 1, 1999; 252 (2): 342-51.


Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties., Itano N, Sawai T, Yoshida M, Lenas P, Yamada Y, Imagawa M, Shinomura T, Hamaguchi M, Yoshida Y, Ohnuki Y, Miyauchi S, Spicer AP, McDonald JA, Kimata K., J Biol Chem. August 27, 1999; 274 (35): 25085-92.


Hyaluronan synthase expression in bovine eyes., Usui T, Suzuki K, Kaji Y, Amano S, Miyata K, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. March 1, 1999; 40 (3): 563-7.


Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells., Sugiyama Y, Shimada A, Sayo T, Sakai S, Inoue S., J Invest Dermatol. February 1, 1998; 110 (2): 116-21.


Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family., Spicer AP, McDonald JA., J Biol Chem. January 23, 1998; 273 (4): 1923-32.              


Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis., Kumari K, Weigel PH., J Biol Chem. December 19, 1997; 272 (51): 32539-46.


Chromosomal localization of the human and mouse hyaluronan synthase genes., Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA., Genomics. May 1, 1997; 41 (3): 493-7.

???pagination.result.page??? 1 2 ???pagination.result.next???