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Summary Expression Phenotypes Gene Literature (136) GO Terms (2) Nucleotides (360) Proteins (46) Interactants (950) Wiki
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RECQL4 is not critical for firing of human DNA replication origins., Padayachy L, Ntallis SG, Halazonetis TD., Sci Rep. April 2, 2024; 14 (1): 7708.        

Cinnamic Acid and Caffeic Acid Effects on Gastric Tight Junction Proteins Analyzed in Xenopus laevis Oocytes., Vollstädt ML, Stein L, Brunner N, Amasheh S., Membranes (Basel). February 1, 2024; 14 (2):           

Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index., Fu L, Wang S, Liu L, Shibata Y, Okada M, Luu N, Shi YB, Shi YB., Cells. January 29, 2024; 13 (3):           

Cannabidiol Strengthening of Gastric Tight Junction Complexes Analyzed in an Improved Xenopus Oocyte Assay., Stein L, Vollstaedt ML, Amasheh S., Membranes (Basel). January 8, 2024; 14 (1):             

Characterization of Na+ currents regulating intrinsic excitability of optic tectal neurons., Thompson AC, Aizenman CD., Life Sci Alliance. January 1, 2024; 7 (1):                         

β-Catenin and SOX2 Interaction Regulate Visual Experience-Dependent Cell Homeostasis in the Developing Xenopus Thalamus., Gao J, Lu Y, Luo Y, Duan X, Chen P, Zhang X, Wu X, Qiu M, Shen W., Int J Mol Sci. September 2, 2023; 24 (17):                 

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K, Barak T, Kaulen LD, Henegariu O, Jin SC, Aguilera SM, Yalbir E, Goles G, Nishimura S, Miyagishima D, Djenoune L, Altinok S, Rai DK, Viviano S, Prendergast A, Zerillo C, Ozcan K, Baran B, Sencar L, Goc N, Yarman Y, Ercan-Sencicek AG, Bilguvar K, Lifton RP, Moliterno J, Louvi A, Yuan S, Deniz E, Brueckner M, Gunel M., Proc Natl Acad Sci U S A. April 18, 2023; 120 (16): e2214997120.                                            

BDNF signaling in correlation-dependent structural plasticity in the developing visual system., Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES., PLoS Biol. April 1, 2023; 21 (4): e3002070.          

Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation., Schroeter CB, Nelke C, Schewe M, Spohler L, Herrmann AM, Müntefering T, Huntemann N, Kuzikov M, Gribbon P, Albrecht S, Bock S, Hundehege P, Neelsen LC, Baukrowitz T, Seebohm G, Wünsch B, Bittner S, Ruck T, Budde T, Meuth SG., Biol Chem. March 28, 2023; 404 (4): 355-375.              

Asbestos Fibers Enhance the TMEM16A Channel Activity in Xenopus Oocytes., Bernareggi A, Zangari M, Constanti A, Zacchi P, Borelli V, Mangogna A, Lorenzon P, Zabucchi G., Membranes (Basel). February 1, 2023; 13 (2):                     

Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption., Vit G, Hirth A, Neugebauer N, Kraft BN, Sigismondo G, Cazzola A, Tessmer C, Duro J, Krijgsveld J, Hofmann I, Berger M, Klüter H, Niehrs C, Nilsson J, Krämer A., Cell Death Discov. December 8, 2022; 8 (1): 484.                

The translation regulator Zar1l controls timing of meiosis in Xenopus oocytes., Heim A, Niedermeier ML, Stengel F, Mayer TU., Development. November 1, 2022; 149 (21):                           

Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism., Frampton DJA, Choudhury K, Nikesjö J, Delemotte L, Liin SI., Elife. June 1, 2022; 11     

Topographic map formation and the effects of NMDA receptor blockade in the developing visual system., Li VJ, Schohl A, Ruthazer ES., Proc Natl Acad Sci U S A. February 22, 2022; 119 (8):                                   

Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis., Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ., PLoS Genet. January 18, 2022; 18 (1): e1010012.                                                              

Epigenetic regulation of GABAergic differentiation in the developing brain., Gao J, Luo Y, Lu Y, Wu X, Chen P, Zhang X, Han L, Qiu M, Shen W., Front Cell Neurosci. January 1, 2022; 16 988732.            

An early midbrain sensorimotor pathway is involved in the timely initiation and direction of swimming in the hatchling Xenopus laevis tadpole., Larbi MC, Messa G, Jalal H, Koutsikou S., Front Neural Circuits. January 1, 2022; 16 1027831.                

The Roles of Amphibian (Xenopus laevis) Macrophages during Chronic Frog Virus 3 Infections., Hossainey MRH, Yaparla A, Hauser KA, Moore TE, Grayfer L., Viruses. November 18, 2021; 13 (11):               

Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus., Ciardo D, Haccard O, Narassimprakash H, Cornu D, Guerrera IC, Goldar A, Marheineke K., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.                                        

Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis., Buisine N, Grimaldi A, Jonchere V, Rigolet M, Blugeon C, Hamroune J, Sachs LM., Cells. September 9, 2021; 10 (9):               

Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation., Drouyer M, Bolliger MF, Lobbestael E, Van den Haute C, Emanuele M, Lefebvre R, Sibran W, De Wit T, Leghay C, Mutez E, Dzamko N, Halliday GM, Murayama S, Martoriati A, Cailliau K, Bodart JF, Chartier-Harlin MC, Baekelandt V, Nichols RJ, Taymans JM., Neurobiol Dis. September 1, 2021; 157 105426.                                

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue., Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S., Curr Biol. August 9, 2021; 31 (15): 3409-3418.e6.                  

mem-iLID, a fast and economic protein purification method., Tang R, Yang S, Nagel G, Gao S., Biosci Rep. July 30, 2021; 41 (7):             

Three-dimensional folding dynamics of the Xenopus tropicalis genome., Niu L, Shen W, Shi Z, Tan Y, He N, Wan J, Sun J, Zhang Y, Huang Y, Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Chen Y, Li L, Hou C., Nat Genet. July 1, 2021; 53 (7): 1075-1087.                                    

Further evidence for functional recovery of AQP2 mutations associated with nephrogenic diabetes insipidus., Bissonnette P, Lussier Y, Matar J, Leduc-Nadeau A, Da Cal S, Arthus MF, Unwin RJ, Steinke J, Rangaswamy D, Bichet DG., Physiol Rep. June 1, 2021; 9 (11): e14866.              

Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry., Tavernier N, Thomas Y, Vigneron S, Maisonneuve P, Orlicky S, Mader P, Regmi SG, Van Hove L, Levinson NM, Gasmi-Seabrook G, Joly N, Poteau M, Velez-Aguilera G, Gavet O, Castro A, Dasso M, Lorca T, Sicheri F, Pintard L., Nat Commun. March 26, 2021; 12 (1): 1899.                  

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility., Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F., PLoS Biol. January 6, 2021; 19 (1): e3001060.                                            

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM., Sci Rep. December 9, 2020; 10 (1): 21555.            

Bruton's Tyrosine Kinase Inhibition Promotes Myelin Repair., Martin E, Aigrot MS, Grenningloh R, Stankoff B, Lubetzki C, Boschert U, Zalc B., Brain Plast. October 1, 2020; 5 (2): 123-133.        

Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development., Kesner P, Schohl A, Warren EC, Ma F, Ruthazer ES., Cell Rep. July 28, 2020; 32 (4): 107955.                                            

SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development., Falbo L, Raspelli E, Romeo F, Fiorani S, Pezzimenti F, Casagrande F, Costa I, Parazzoli D, Costanzo V., Nat Commun. March 12, 2020; 11 (1): 1345.                

An in vivo brain-bacteria interface: the developing brain as a key regulator of innate immunity., Herrera-Rincon C, Paré JF, Martyniuk CJ, Jannetty SK, Harrison C, Fischer A, Dinis A, Keshari V, Novak R, Levin M., NPJ Regen Med. February 4, 2020; 5 2.                        

An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells., Ollech D, Pflästerer T, Shellard A, Zambarda C, Spatz JP, Marcq P, Mayor R, Wombacher R, Cavalcanti-Adam EA., Nat Commun. January 24, 2020; 11 (1): 472.                                  

Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers., Singh A, Allen D, Fracassi A, Tumurbaatar B, Natarajan C, Scaduto P, Woltjer R, Kayed R, Limon A, Krishnan B, Taglialatela G., J Alzheimers Dis. January 1, 2020; 78 (4): 1661-1678.          

TPX2 silencing exerts anti‑tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway., Huang DH, Jian J, Li S, Zhang Y, Liu LZ., Int J Mol Med. December 1, 2019; 44 (6): 2113-2122.          

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, Harbour JW., Sci Adv. September 18, 2019; 5 (9): eaax1738.        

The molecular determinants of R-roscovitine block of hERG channels., Cernuda B, Fernandes CT, Allam SM, Orzillo M, Suppa G, Chia Chang Z, Athanasopoulos D, Buraei Z., PLoS One. September 3, 2019; 14 (9): e0217733.                      

The SNPs in myoD gene from normal muscle developing individuals have no effect on muscle mass., Ding S, Nie Y, Zhang X, Liu X, Wang C, Wang C, Yuan R, Chen K, Zhu Q, Cai S, Fang Y, Chen Y, Chen Y, Mo D., BMC Genet. September 2, 2019; 20 (1): 72.      

SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility., Awadia S, Huq F, Arnold TR, Goicoechea SM, Sun YJ, Hou T, Kreider-Letterman G, Massimi P, Banks L, Fuentes EJ, Miller AL, Miller AL, Garcia-Mata R., J Cell Biol. August 5, 2019; 218 (8): 2699-2725.                                                  

Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility., Robson A, Makova SZ, Barish S, Zaidi S, Mehta S, Drozd J, Jin SC, Gelb BD, Seidman CE, Chung WK, Lifton RP, Khokha MK, Brueckner M., Proc Natl Acad Sci U S A. July 9, 2019; 116 (28): 14049-14054.                                  

Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)., Tuladhar R, Yarravarapu N, Ma Y, Zhang C, Herbert J, Kim J, Chen C, Lum L., J Biol Chem. April 19, 2019; 294 (16): 6273-6282.              

Myelopoiesis of the Amphibian Xenopus laevis Is Segregated to the Bone Marrow, Away From Their Hematopoietic Peripheral Liver., Yaparla A, Reeves P, Grayfer L., Front Immunol. April 4, 2019; 10 3015.              

Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability., Marshall LN, Vivien CJ, Girardot F, Péricard L, Scerbo P, Palmier K, Demeneix BA, Coen L., Proc Natl Acad Sci U S A. February 26, 2019; 116 (9): 3614-3623.          

On the mechanism of the electrophysiological changes and membrane lesions induced by asbestos fiber exposure in Xenopus laevis oocytes., Bernareggi A, Conte G, Constanti A, Borelli V, Vita F, Zabucchi G., Sci Rep. February 14, 2019; 9 (1): 2014.                      

Six1 and Irx1 have reciprocal interactions during cranial placode and otic vesicle formation., Sullivan CH, Majumdar HD, Neilson KM, Moody SA., Dev Biol. February 1, 2019; 446 (1): 68-79.                      

Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation., De Silva AM, Manville RW, Abbott GW., Sci Adv. November 14, 2018; 4 (11): eaav0824.            

Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb., Herrera-Rincon C, Golding AS, Moran KM, Harrison C, Martyniuk CJ, Guay JA, Zaltsman J, Carabello H, Kaplan DL, Levin M., Cell Rep. November 6, 2018; 25 (6): 1593-1609.e7.                            

The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development., Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC., Sci Rep. October 30, 2018; 8 (1): 16029.                                      

Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition., Beck S, Yu-Strzelczyk J, Pauls D, Constantin OM, Gee CE, Ehmann N, Kittel RJ, Nagel G, Gao S., Front Neurosci. October 2, 2018; 12 643.                    

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

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