Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (190) GO Terms (26) Nucleotides (140) Proteins (57) Interactants (149) Wiki
XB-GENEPAGE-5921461

Papers associated with kcnq1



???displayGene.coCitedPapers???
2 ???displayGene.morpholinoPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 3 4 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy., Yang WP, Levesque PC, Little WA, Conder ML, Ramakrishnan P, Neubauer MG, Blanar MA., J Biol Chem. July 31, 1998; 273 (31): 19419-23.

Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias., Waldegger S, Fakler B, Bleich M, Barth P, Hopf A, Schulte U, Busch AE, Aller SG, Forrest JN, Greger R, Lang F., Pflugers Arch. January 1, 1999; 437 (2): 298-304.

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness., Kubisch C, Schroeder BC, Friedrich T, Lütjohann B, El-Amraoui A, Marlin S, Petit C, Jentsch TJ., Cell. February 5, 1999; 96 (3): 437-46.

Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels., Pusch M, Bertorello L, Conti F., Biophys J. January 1, 2000; 78 (1): 211-26.

A constitutively open potassium channel formed by KCNQ1 and KCNE3., Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ., Nature. January 13, 2000; 403 (6766): 196-9.

A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly., Schmitt N, Schwarz M, Peretz A, Abitbol I, Attali B, Pongs O., EMBO J. February 1, 2000; 19 (3): 332-40.

Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991., Wang HS, Brown BS, McKinnon D, Cohen IS., Mol Pharmacol. June 1, 2000; 57 (6): 1218-23.

KCNE1 reverses the response of the human K+ channel KCNQ1 to cytosolic pH changes and alters its pharmacology and sensitivity to temperature., Unsöld B, Kerst G, Brousos H, Hübner M, Schreiber R, Nitschke R, Greger R, Bleich M., Pflugers Arch. December 1, 2000; 441 (2-3): 368-78.

Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols., Lerche C, Seebohm G, Wagner CI, Scherer CR, Dehmelt L, Abitbol I, Gerlach U, Brendel J, Attali B, Busch AE., Br J Pharmacol. December 1, 2000; 131 (8): 1503-6.

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel., Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J., EMBO J. December 1, 2000; 19 (23): 6326-30.

Mechanisms of I(Ks) suppression in LQT1 mutants., Bianchi L, Priori SG, Napolitano C, Surewicz KA, Dennis AT, Memmi M, Schwartz PJ, Brown AM., Am J Physiol Heart Circ Physiol. December 1, 2000; 279 (6): H3003-11.

KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology., Søgaard R, Ljungstrøm T, Pedersen KA, Olesen SP, Jensen BS., Am J Physiol Cell Physiol. April 1, 2001; 280 (4): C859-66.

Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome., Seebohm G, Scherer CR, Busch AE, Lerche C., J Biol Chem. April 27, 2001; 276 (17): 13600-5.

Regulation and properties of KCNQ1 (K(V)LQT1) and impact of the cystic fibrosis transmembrane conductance regulator., Boucherot A, Schreiber R, Kunzelmann K., J Membr Biol. July 1, 2001; 182 (1): 39-47.

Dependence of I(Ks) biophysical properties on the expression system., Seebohm G, Lerche C, Busch AE, Bachmann A., Pflugers Arch. September 1, 2001; 442 (6): 891-5.

A spectrum of functional effects for disease causing mutations in the Jervell and Lange-Nielsen syndrome., Huang L, Bitner-Glindzicz M, Tranebjaerg L, Tinker A., Cardiovasc Res. September 1, 2001; 51 (4): 670-80.

Properties and function of KCNQ1 K+ channels isolated from the rectal gland of Squalus acanthias., Kerst G, Beschorner U, Unsöld B, von Hahn T, Schreiber R, Greger R, Gerlach U, Lang HJ, Kunzelmann K, Bleich M., Pflugers Arch. October 1, 2001; 443 (1): 146-54.

Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium., MacVinish LJ, Guo Y, Dixon AK, Murrell-Lagnado RD, Cuthbert AW., Mol Pharmacol. October 1, 2001; 60 (4): 753-60.

A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B., Seebohm G, Lerche C, Pusch M, Steinmeyer K, Brüggemann A, Busch AE., Br J Pharmacol. December 1, 2001; 134 (8): 1647-54.

The oxidant thimerosal modulates gating behavior of KCNQ1 by interaction with the channel outer shell., Kerst G, Brousos H, Schreiber R, Nitschke R, Hug MJ, Greger R, Bleich M., J Membr Biol. March 15, 2002; 186 (2): 89-100.

A truncated splice variant of KCNQ1 cloned from rat heart., Yamada Y, Chen X, Kobayashi T, Kamada Y, Nagashima M, Tsutsuura M, Seki S, Yamakage M, Namiki A, Tohse N., Biochem Biophys Res Commun. June 7, 2002; 294 (2): 199-204.

KCNE4 is an inhibitory subunit to the KCNQ1 channel., Grunnet M, Jespersen T, Rasmussen HB, Ljungstrøm T, Jorgensen NK, Olesen SP, Klaerke DA., J Physiol. July 1, 2002; 542 (Pt 1): 119-30.

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current., Angelo K, Jespersen T, Grunnet M, Nielsen MS, Klaerke DA, Olesen SP., Biophys J. October 1, 2002; 83 (4): 1997-2006.

Modulation of homomeric and heteromeric KCNQ1 channels by external acidification., Peretz A, Schottelndreier H, Aharon-Shamgar LB, Attali B., J Physiol. December 15, 2002; 545 (3): 751-66.

A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly., Schwake M, Jentsch TJ, Friedrich T., EMBO Rep. January 1, 2003; 4 (1): 76-81.

Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms., Embark HM, Böhmer C, Vallon V, Luft F, Lang F., Pflugers Arch. February 1, 2003; 445 (5): 601-6.

P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport., Köttgen M, Löffler T, Jacobi C, Nitschke R, Pavenstädt H, Schreiber R, Frische S, Nielsen S, Leipziger J., J Clin Invest. February 1, 2003; 111 (3): 371-9.

C-terminal domains implicated in the functional surface expression of potassium channels., Jenke M, Sánchez A, Monje F, Stühmer W, Weseloh RM, Pardo LA., EMBO J. February 3, 2003; 22 (3): 395-403.

Clinical and electrophysiological characterization of a novel mutation (F193L) in the KCNQ1 gene associated with long QT syndrome., Yamaguchi M, Shimizu M, Ino H, Terai H, Hayashi K, Mabuchi H, Hoshi N, Higashida H., Clin Sci (Lond). April 1, 2003; 104 (4): 377-82.

RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW., J Biol Chem. April 4, 2003; 278 (14): 11739-45.

Novel gene hKCNE4 slows the activation of the KCNQ1 channel., Teng S, Ma L, Zhen Y, Lin C, Bähring R, Vardanyan V, Pongs O, Hui R., Biochem Biophys Res Commun. April 11, 2003; 303 (3): 808-13.

C-terminal interaction of KCNQ2 and KCNQ3 K+ channels., Maljevic S, Lerche C, Seebohm G, Alekov AK, Busch AE, Lerche H., J Physiol. April 15, 2003; 548 (Pt 2): 353-60.

Pore- and state-dependent cadmium block of I(Ks) channels formed with MinK-55C and wild-type KCNQ1 subunits., Chen H, Sesti F, Goldstein SA., Biophys J. June 1, 2003; 84 (6): 3679-89.

KCNQ1 channels sense small changes in cell volume., Grunnet M, Jespersen T, MacAulay N, Jørgensen NK, Schmitt N, Pongs O, Olesen SP, Klaerke DA., J Physiol. June 1, 2003; 549 (Pt 2): 419-27.

Molecular determinants of KCNQ1 channel block by a benzodiazepine., Seebohm G, Chen J, Strutz N, Culberson C, Lerche C, Sanguinetti MC., Mol Pharmacol. July 1, 2003; 64 (1): 70-7.

Characterization of a novel Long QT syndrome mutation G52R-KCNE1 in a Chinese family., Ma L, Lin C, Teng S, Chai Y, Bähring R, Vardanyan V, Li L, Pongs O, Hui R., Cardiovasc Res. September 1, 2003; 59 (3): 612-9.

Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels., Ljungstrom T, Grunnet M, Jensen BS, Olesen SP., Pflugers Arch. September 1, 2003; 446 (6): 684-94.

Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex., Chen H, Kim LA, Rajan S, Xu S, Goldstein SA., Neuron. September 25, 2003; 40 (1): 15-23.

Tight coupling of rubidium conductance and inactivation in human KCNQ1 potassium channels., Seebohm G, Sanguinetti MC, Pusch M., J Physiol. October 15, 2003; 552 (Pt 2): 369-78.

Pharmacological activation of normal and arrhythmia-associated mutant KCNQ1 potassium channels., Seebohm G, Pusch M, Chen J, Sanguinetti MC., Circ Res. November 14, 2003; 93 (10): 941-7.

The therapeutic potential of neuronal KCNQ channel modulators., Gribkoff VK., Expert Opin Ther Targets. December 1, 2003; 7 (6): 737-48.

Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval., Busjahn A, Seebohm G, Maier G, Toliat MR, Nürnberg P, Aydin A, Luft FC, Lang F., Cell Physiol Biochem. January 1, 2004; 14 (3): 135-42.

Effective long-term control of cardiac events with beta-blockers in a family with a common LQT1 mutation., Wedekind H, Schwarz M, Hauenschild S, Djonlagic H, Haverkamp W, Breithardt G, Wülfing T, Pongs O, Isbrandt D, Schulze-Bahr E., Clin Genet. March 1, 2004; 65 (3): 233-41.

External barium affects the gating of KCNQ1 potassium channels and produces a pore block via two discrete sites., Gibor G, Yakubovich D, Peretz A, Attali B., J Gen Physiol. July 1, 2004; 124 (1): 83-102.                                

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif., Jespersen T, Rasmussen HB, Grunnet M, Jensen HS, Angelo K, Dupuis DS, Vogel LK, Jorgensen NK, Klaerke DA, Olesen SP., J Cell Sci. September 1, 2004; 117 (Pt 19): 4517-26.

Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J, Thomas D, Khalil M, Wimmer AB, Koenen M, Licka M, Wu K, Kiehn J, Brockmeier K, Kreye VA, Karle CA, Katus HA, Ulmer HE, Schoels W., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.

KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels., Gage SD, Kobertz WR., J Gen Physiol. December 1, 2004; 124 (6): 759-71.                  

Analysis of QT Interval Prolongation With Heart Failure by Simulation of Repolarization Process., Yamaguchi T, Arafune T, Sakuma I, Watanabe E, Shibata N, Honjo H, Kodama I, Kamiya K., Conf Proc IEEE Eng Med Biol Soc. January 1, 2005; 2005 7309-12.

Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels., Seebohm G, Westenskow P, Lang F, Sanguinetti MC., J Physiol. March 1, 2005; 563 (Pt 2): 359-68.

hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics., Grunnet M, Olesen SP, Klaerke DA, Jespersen T., Biochem Biophys Res Commun. March 25, 2005; 328 (4): 1146-53.

???pagination.result.page??? 1 2 3 4 ???pagination.result.next???