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Summary Expression Phenotypes Gene Literature (1045) GO Terms (5) Nucleotides (437) Proteins (71) Interactants (3518) Wiki
XB--6052813

Papers associated with myc (and Disease Ontology)



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Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E, Du YZ, Mullor JL, Casas E, Allen WP, Gillessen-Kaesbach G, Roeder ER, Ming JE, Ruiz i Altaba A, Muenke M., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13424-9.          

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos., Tao Q, Tao Q, Yokota C, Puck H, Kofron M, Birsoy B, Yan D, Asashima M, Wylie CC, Lin X, Heasman J., Cell. March 25, 2005; 120 (6): 857-71.            

The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition., Cruciat CM, Hassler C, Niehrs C., J Biol Chem. May 5, 2006; 281 (18): 12986-93.                        

Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, Galloway DA, Gu W, Gautier J, Dalla-Favera R., Nature. July 26, 2007; 448 (7152): 445-51.      

Transcription factor HNF1beta and novel partners affect nephrogenesis., Dudziak K, Mottalebi N, Senkel S, Edghill EL, Rosengarten S, Roose M, Bingham C, Ellard S, Ryffel GU., Kidney Int. July 1, 2008; 74 (2): 210-7.                  

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y, Trojer P, Xu CF, Cheung P, Kuo A, Drury WJ, Qiao Q, Neubert TA, Xu RM, Gozani O, Reinberg D., J Biol Chem. December 4, 2009; 284 (49): 34283-95.              

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival., Rauschenberger K, Schöler K, Sass JO, Sauer S, Djuric Z, Rumig C, Wolf NI, Okun JG, Kölker S, Schwarz H, Fischer C, Grziwa B, Runz H, Nümann A, Shafqat N, Kavanagh KL, Hämmerling G, Wanders RJ, Shield JP, Wendel U, Stern D, Nawroth P, Hoffmann GF, Bartram CR, Arnold B, Bierhaus A, Oppermann U, Steinbeisser H, Zschocke J., EMBO Mol Med. February 1, 2010; 2 (2): 51-62.                        

Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S, Cheng F, Liang J, Wu W, Zhang J., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase., Sareen A, Chaudhury I, Adams N, Sobeck A., Nucleic Acids Res. September 1, 2012; 40 (17): 8425-39.          

A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome., Tanaka K, Kato A, Angelocci C, Watanabe M, Kato Y., Dev Biol. March 1, 2014; 387 (1): 28-36.        

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling., Iwasaki Y, Thomsen GH., Development. October 1, 2014; 141 (19): 3740-51.                                          

Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels., Vingtdeux V, Tanis JE, Chandakkar P, Zhao H, Dreses-Werringloer U, Campagne F, Foskett JK, Marambaud P., PLoS One. November 6, 2014; 9 (11): e112484.        

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM., Dev Biol. November 15, 2014; 395 (2): 317-330.                  

Osmostress-induced apoptosis in Xenopus oocytes: role of stress protein kinases, calpains and Smac/DIABLO., Ben Messaoud N, Yue J, Valent D, Katzarova I, López JM., PLoS One. January 1, 2015; 10 (4): e0124482.            

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ, Philpott A., Dis Model Mech. May 1, 2015; 8 (5): 429-41.                

Transcriptional regulator PRDM12 is essential for human pain perception., Chen YC, Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J., Nat Genet. July 1, 2015; 47 (7): 803-8.          

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T, Fisher M, Fisher M, Nakajima K, Odeleye AO, Zimmerman KB, Fish MB, Yaoita Y, Chojnowski JL, Lauderdale JD, Netland PA, Grainger RM., Dev Biol. December 15, 2015; 408 (2): 328-44.                              

The involvement of PCP proteins in radial cell intercalations during Xenopus embryonic development., Ossipova O, Chu CW, Fillatre J, Brott BK, Itoh K, Sokol SY., Dev Biol. December 15, 2015; 408 (2): 316-27.                              

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmström A, Pera EM., Dis Model Mech. June 1, 2016; 9 (6): 607-20.                                      

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Alfandari D, Moody SA., Dev Biol. January 15, 2017; 421 (2): 171-182.                    

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M, Kanwal N, Dietmann P, Seigfried FA, Hempel A, Schütz D, Reim D, Engels R, Linnemann A, Schmeisser MJ, Bockmann J, Kühl M, Boeckers TM, Kühl SJ., Development. January 15, 2017; 144 (2): 321-333.                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus., Bae CJ, Hong CS, Saint-Jeannet JP., Biochem Biophys Res Commun. January 15, 2018; 495 (3): 2257-2263.        

Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B, Tran U, Wessely O., Development. March 22, 2018; 145 (6):                         

The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture., Takahashi C, Miyatake K, Kusakabe M, Nishida E., J Biol Chem. June 1, 2018; 293 (22): 8342-8361.                                      

Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate., Chuykin I, Ossipova O, Sokol SY., Elife. September 26, 2018; 7                                                           

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S, Veschambre P, Fédou S, Rezvani HR, Thézé N, Thiébaud P., Dev Biol. March 15, 2019; 447 (2): 200-213.                                  

N-glycosylation-dependent regulation of hK2P17.1 currents., Wiedmann F, Schlund D, Voigt N, Ratte A, Kraft M, Katus HA, Schmidt C., Mol Biol Cell. June 1, 2019; 30 (12): 1425-1436.                      

Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity., Lazarov E, Hillebrand M, Schröder S, Ternka K, Hofhuis J, Ohlenbusch A, Barrantes-Freer A, Pardo LA, Fruergaard MU, Nissen P, Brockmann K, Gärtner J, Rosewich H., Neurobiol Dis. September 1, 2020; 143 105012.        

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Mcrs1 interacts with Six1 to influence early craniofacial and otic development., Neilson KM, Keer S, Bousquet N, Macrorie O, Majumdar HD, Kenyon KL, Alfandari D, Alfandari D, Moody SA., Dev Biol. November 1, 2020; 467 (1-2): 39-50.                  

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Kowalczyk I, Lee C, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Görne J, Wallingford JB, Hammes A, Feistel K., Development. January 26, 2021; 148 (2):                                   

Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly., Macken WL, Godwin A, Wheway G, Stals K, Nazlamova L, Ellard S, Alfares A, Aloraini T, AlSubaie L, Alfadhel M, Alajaji S, Wai HA, Self J, Douglas AGL, Kao AP, Guille M, Baralle D., Genome Med. February 25, 2021; 13 (1): 34.            

HPF1-dependent PARP activation promotes LIG3-XRCC1-mediated backup pathway of Okazaki fragment ligation., Kumamoto S, Nishiyama A, Chiba Y, Miyashita R, Konishi C, Azuma Y, Nakanishi M., Nucleic Acids Res. May 21, 2021; 49 (9): 5003-5016.            

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY, Zhou YM, Liao ZQ, Zhong JW, Liu YB, Zhao H, Liang CQ, Huang RJ, Park KS, Feng SS, Zheng L, Cai DQ, Qi XF., NPJ Regen Med. June 29, 2021; 6 (1): 36.                    

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue., Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S., Curr Biol. August 9, 2021; 31 (15): 3409-3418.e6.                  

Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development., Tavares ALP, Jourdeuil K, Neilson KM, Majumdar HD, Moody SA., Development. September 1, 2021; 148 (17):                       

Function of chromatin modifier Hmgn1 during neural crest and craniofacial development., Ihewulezi C, Saint-Jeannet JP., Genesis. October 1, 2021; 59 (10): e23447.              

CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping., Naert T, Tulkens D, Van Nieuwenhuysen T, Przybyl J, Demuynck S, van de Rijn M, Al-Jazrawe M, Alman BA, Coucke PJ, De Leeneer K, Vanhove C, Savvides SN, Creytens D, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. November 23, 2021; 118 (47):                             

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M, Kühl SJ., Front Cell Dev Biol. January 1, 2022; 10 777121.                        

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P, Perfetto M, Lu C, Zhuo M, Bahudhanapati H, Li J, Chen WC, Kulkarni P, Christian L, Liu J, Yien YY, Yu C, Wei S., J Biol Chem. August 1, 2022; 298 (8): 102225.                            

Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ., PLoS One. August 2, 2022; 17 (8): e0273507.                        

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A, Cousin H, Horr B, Alfandari D, Alfandari D., Front Cell Dev Biol. January 1, 2023; 11 1271178.                      

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation., Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Alfandari D, Moody SA., Front Cell Dev Biol. January 1, 2023; 11 1274788.          

Characteristic tetraspanin expression patterns mark various tissues during early Xenopus development., Kuriyama S, Tanaka M., Dev Growth Differ. February 1, 2023; 65 (2): 109-119.                

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders., Kaiyrzhanov R, Rad A, Lin SJ, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Karimiani EG, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Tayfun GA, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Monajemi GB, Mohammadi P, Samie S, Banu SH, Pinto Basto J, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Issa AH, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R., Brain. April 4, 2024; 147 (4): 1436-1456.                            

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