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Summary Expression Phenotypes Gene Literature (94) GO Terms (4) Nucleotides (72) Proteins (43) Interactants (60) Wiki
XB-GENEPAGE-6456767

Papers associated with slco1a2



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Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta., Lofthouse EM, Torrens C, Manousopoulou A, Nahar M, Cleal JK, O'Kelly IM, Sengers BG, Garbis SD, Lewis RM., FASEB J. July 1, 2019; 33 (7): 8211-8220.              


Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux., Lofthouse EM, Cleal JK, O'Kelly IM, Sengers BG, Lewis RM., Biochem Biophys Res Commun. November 17, 2018; 506 (1): 237-242.          


Interaction of Purinergic P2X4 and P2X7 Receptor Subunits., Schneider M, Prudic K, Pippel A, Klapperstück M, Braam U, Müller CE, Schmalzing G, Markwardt F., Front Pharmacol. May 26, 2017; 8 860.                        


Characterization of 22 Antituberculosis Drugs for Inhibitory Interaction Potential on Organic Anionic Transporter Polypeptide (OATP)-Mediated Uptake., Parvez MM, Jung JA, Shin HJ, Kim DH, Shin JG., Antimicrob Agents Chemother. April 22, 2016; 60 (5): 3096-105.


Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride., Fujita D, Saito Y, Nakanishi T, Tamai I., Drug Metab Dispos. January 1, 2016; 44 (1): 1-7.


Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS., Gao B, Vavricka SR, Meier PJ, Stieger B., Pflugers Arch. July 1, 2015; 467 (7): 1481-1493.


Organic anion transporting polypeptide-mediated transport of, and inhibition by, asunaprevir, an inhibitor of hepatitis C virus NS3 protease., Eley T, Han YH, Huang SP, He B, Li W, Bedford W, Stonier M, Gardiner D, Sims K, Rodrigues AD, Bertz RJ., Clin Pharmacol Ther. February 1, 2015; 97 (2): 159-66.


Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species., Taub ME, Ludwig-Schwellinger E, Ishiguro N, Kishimoto W, Yu H, Wagner K, Tweedie D., Chem Res Toxicol. January 20, 2015; 28 (1): 103-15.


Connexin hemichannel and pannexin channel electrophysiology: how do they differ?, Patel D, Zhang X, Veenstra RD., FEBS Lett. April 17, 2014; 588 (8): 1372-8.


Characterization of SLCO5A1/OATP5A1, a solute carrier transport protein with non-classical function., Sebastian K, Detro-Dassen S, Rinis N, Fahrenkamp D, Müller-Newen G, Merk HF, Schmalzing G, Zwadlo-Klarwasser G, Baron JM., PLoS One. December 9, 2013; 8 (12): e83257.          


Rilpivirine inhibits drug transporters ABCB1, SLC22A1, and SLC22A2 in vitro., Moss DM, Liptrott NJ, Curley P, Siccardi M, Back DJ, Owen A., Antimicrob Agents Chemother. November 1, 2013; 57 (11): 5612-8.


Intestinal absorption mechanism of mirabegron, a potent and selective β₃-adrenoceptor agonist: involvement of human efflux and/or influx transport systems., Takusagawa S, Ushigome F, Nemoto H, Takahashi Y, Li Q, Kerbusch V, Miyashita A, Iwatsubo T, Usui T., Mol Pharm. May 6, 2013; 10 (5): 1783-94.


The food dye FD&C Blue No. 1 is a selective inhibitor of the ATP release channel Panx1., Wang J, Jackson DG, Dahl G., J Gen Physiol. May 1, 2013; 141 (5): 649-56.              


Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5., Arakawa H, Shirasaka Y, Haga M, Nakanishi T, Tamai I., Biopharm Drug Dispos. September 1, 2012; 33 (6): 332-41.


Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)., Visentin M, Chang MH, Romero MF, Zhao R, Goldman ID., Mol Pharmacol. February 1, 2012; 81 (2): 134-42.


Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport., Svoboda M, Wlcek K, Taferner B, Hering S, Stieger B, Tong D, Zeillinger R, Thalhammer T, Jäger W., Biomed Pharmacother. September 1, 2011; 65 (6): 417-26.


Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein., Shirasaka Y, Suzuki K, Nakanishi T, Tamai I., J Pharm Sci. September 1, 2011; 100 (9): 3843-53.


Environmental and genetic factors affecting transport of imatinib by OATP1A2., Eechoute K, Franke RM, Loos WJ, Scherkenbach LA, Boere I, Verweij J, Gurney H, Kim RB, Tirona RG, Mathijssen RH, Sparreboom A., Clin Pharmacol Ther. June 1, 2011; 89 (6): 816-20.


Raltegravir is a substrate for SLC22A6: a putative mechanism for the interaction between raltegravir and tenofovir., Moss DM, Kwan WS, Liptrott NJ, Smith DL, Siccardi M, Khoo SH, Back DJ, Owen A., Antimicrob Agents Chemother. February 1, 2011; 55 (2): 879-87.


Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1., Shirasaka Y, Suzuki K, Shichiri M, Nakanishi T, Tamai I., Drug Metab Pharmacokinet. January 1, 2011; 26 (2): 171-9.


Characterization of digoxin uptake in sandwich-cultured human hepatocytes., Kimoto E, Chupka J, Xiao Y, Bi YA, Duignan DB., Drug Metab Dispos. January 1, 2011; 39 (1): 47-53.


[Molecular cloning and functional characterization of a novel gene encoding human prostaglandin carrier, hPrC]., Kobayashi Y, Nojima J, Ohbayashi M, Kohyama N, Yamamoto T., Yakugaku Zasshi. January 1, 2011; 131 (10): 1493-501.


Intestinal absorption mechanism of tebipenem pivoxil, a novel oral carbapenem: involvement of human OATP family in apical membrane transport., Kato K, Shirasaka Y, Kuraoka E, Kikuchi A, Iguchi M, Suzuki H, Shibasaki S, Kurosawa T, Tamai I., Mol Pharm. October 4, 2010; 7 (5): 1747-56.


Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide., Shirasaka Y, Suzuki K, Nakanishi T, Tamai I., Pharm Res. October 1, 2010; 27 (10): 2141-9.


Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis., Connors KA, Korte JJ, Anderson GW, Degitz SJ., Gen Comp Endocrinol. August 1, 2010; 168 (1): 149-59.            


HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms., Hartkoorn RC, Kwan WS, Shallcross V, Chaikan A, Liptrott N, Egan D, Sora ES, James CE, Gibbons S, Bray PG, Back DJ, Khoo SH, Owen A., Pharmacogenet Genomics. February 1, 2010; 20 (2): 112-20.


Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat., Shirasaka Y, Kuraoka E, Spahn-Langguth H, Nakanishi T, Langguth P, Tamai I., J Pharmacol Exp Ther. January 1, 2010; 332 (1): 181-9.


Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters., Hu S, Chen Z, Franke R, Orwick S, Zhao M, Rudek MA, Sparreboom A, Baker SD., Clin Cancer Res. October 1, 2009; 15 (19): 6062-9.


In vitro inhibition of OATP-mediated uptake of phalloidin using bile acid derivatives., Herraez E, Macias RI, Vazquez-Tato J, Vicens M, Monte MJ, Marin JJ., Toxicol Appl Pharmacol. August 15, 2009; 239 (1): 13-20.


Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol., Kato Y, Miyazaki T, Kano T, Sugiura T, Kubo Y, Tsuji A., J Pharm Sci. July 1, 2009; 98 (7): 2529-39.


Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp)., Shirasaka Y, Li Y, Shibue Y, Kuraoka E, Spahn-Langguth H, Kato Y, Langguth P, Tamai I., Pharm Res. March 1, 2009; 26 (3): 560-7.


Interaction of imatinib with human organic ion carriers., Hu S, Franke RM, Filipski KK, Hu C, Orwick SJ, de Bruijn EA, Burger H, Baker SD, Sparreboom A., Clin Cancer Res. May 15, 2008; 14 (10): 3141-8.


Noninvasive monitoring of transporter-substrate interaction at cell membrane., Sakata T, Miyahara Y., Anal Chem. March 1, 2008; 80 (5): 1493-6.


Identification and species similarity of OATP transporters responsible for hepatic uptake of beta-lactam antibiotics., Nakakariya M, Shimada T, Irokawa M, Maeda T, Tamai I., Drug Metab Pharmacokinet. January 1, 2008; 23 (5): 347-55.


Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport., Mahagita C, Grassl SM, Piyachaturawat P, Ballatori N., Am J Physiol Gastrointest Liver Physiol. July 1, 2007; 293 (1): G271-8.


Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake., Vicens M, Medarde M, Macias RI, Larena MG, Villafaina A, Serrano MA, Marin JJ., Bioorg Med Chem. March 15, 2007; 15 (6): 2359-67.


The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver., Meier-Abt F, Hammann-Hänni A, Stieger B, Ballatori N, Boyer JL., Toxicol Appl Pharmacol. February 1, 2007; 218 (3): 274-9.


Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics., Smith NF, Marsh S, Scott-Horton TJ, Hamada A, Mielke S, Mross K, Figg WD, Verweij J, McLeod HL, Sparreboom A., Clin Pharmacol Ther. January 1, 2007; 81 (1): 76-82.


Identification of influx transporter for the quinolone antibacterial agent levofloxacin., Maeda T, Takahashi K, Ohtsu N, Oguma T, Ohnishi T, Atsumi R, Tamai I., Mol Pharm. January 1, 2007; 4 (1): 85-94.


OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?, Briz O, Romero MR, Martinez-Becerra P, Macias RI, Perez MJ, Jimenez F, San Martin FG, Marin JJ., J Biol Chem. October 13, 2006; 281 (41): 30326-35.


Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps., Ballestero MR, Monte MJ, Briz O, Jimenez F, Gonzalez-San Martin F, Marin JJ., Biochem Pharmacol. September 14, 2006; 72 (6): 729-38.


Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants., Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM., J Pharmacol Exp Ther. August 1, 2006; 318 (2): 521-9.


Excretion of fetal biliverdin by the rat placenta-maternal liver tandem., Briz O, Macias RI, Perez MJ, Serrano MA, Marin JJ., Am J Physiol Regul Integr Comp Physiol. March 1, 2006; 290 (3): R749-56.


Carrier-mediated hepatic uptake of a novel nonrenal excretion type uric acid generation inhibitor, Y-700., Sai Y, Kato Y, Nakamura K, Kato S, Nishimura T, Kubo Y, Tamai I, Yang S, Hu Z, Yamada I, Tsuji A., J Pharm Sci. February 1, 2006; 95 (2): 336-47.


The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1., Whitley AC, Sweet DH, Walle T., Drug Metab Dispos. August 1, 2005; 33 (8): 1097-100.


Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1., Chang C, Pang KS, Swaan PW, Ekins S., J Pharmacol Exp Ther. August 1, 2005; 314 (2): 533-41.


Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin., Fischer WJ, Altheimer S, Cattori V, Meier PJ, Dietrich DR, Hagenbuch B., Toxicol Appl Pharmacol. March 15, 2005; 203 (3): 257-63.


Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms., Nozawa T, Minami H, Sugiura S, Tsuji A, Tamai I., Drug Metab Dispos. March 1, 2005; 33 (3): 434-9.


Thyroid hormone transporters., Friesema EC, Jansen J, Milici C, Visser TJ., Vitam Horm. January 1, 2005; 70 137-67.


Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium., Gao B, Huber RD, Wenzel A, Vavricka SR, Ismair MG, Remé C, Meier PJ., Exp Eye Res. January 1, 2005; 80 (1): 61-72.

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