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Summary Expression Phenotypes Gene Literature (56) GO Terms (3) Nucleotides (81) Proteins (41) Interactants (602) Wiki
XB--855770

Papers associated with gbx2.1



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Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus., Pierce SB, Kimelman D., Dev Biol. May 1, 1996; 175 (2): 256-64.          

Anterior structural defects by misexpression of Xgbx-2 in early Xenopus embryos are associated with altered expression of cell adhesion molecules., King MW, King MW, Ndiema M, Neff AW., Dev Dyn. August 1, 1998; 212 (4): 563-79.

The two Xenopus Gbx2 genes exhibit similar, but not identical expression patterns and can affect head formation., Tour E, Pillemer G, Gruenbaum Y, Fainsod A., FEBS Lett. October 26, 2001; 507 (2): 205-9.

A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus., Kiecker C, Niehrs C., Development. November 1, 2001; 128 (21): 4189-201.              

Otx2 can activate the isthmic organizer genetic network in the Xenopus embryo., Tour E, Pillemer G, Gruenbaum Y, Fainsod A., Mech Dev. January 1, 2002; 110 (1-2): 3-13.          

Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation in Xenopus., Tour E, Pillemer G, Gruenbaum Y, Fainsod A., Mech Dev. March 1, 2002; 112 (1-2): 141-51.      

The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation., Glavic A, Gómez-Skarmeta JL, Mayor R., Development. April 1, 2002; 129 (7): 1609-21.                  

The germ cell nuclear factor is required for retinoic acid signaling during Xenopus development., Barreto G, Borgmeyer U, Dreyer C., Mech Dev. April 1, 2003; 120 (4): 415-28.            

Xenopus XsalF: anterior neuroectodermal specification by attenuating cellular responsiveness to Wnt signaling., Onai T, Sasai N, Matsui M, Sasai Y., Dev Cell. July 1, 2004; 7 (1): 95-106.            

Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm., Kurokawa D, Takasaki N, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S., Development. July 1, 2004; 131 (14): 3307-17.      

Knockdown of the complete Hox paralogous group 1 leads to dramatic hindbrain and neural crest defects., McNulty CL, Peres JN, Bardine N, van den Akker WM, Durston AJ., Development. June 1, 2005; 132 (12): 2861-71.                    

Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos., Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM., Development. August 1, 2005; 132 (15): 3381-92.            

Role of X-Delta-2 in the early neural development of Xenopus laevis., Peres JN, Durston AJ., Dev Dyn. March 1, 2006; 235 (3): 802-10.                                              

Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    

Early molecular effects of ethanol during vertebrate embryogenesis., Yelin R, Kot H, Yelin D, Fainsod A., Differentiation. June 1, 2007; 75 (5): 393-403.                    

A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2., Lauberth SM, Bilyeu AC, Firulli BA, Kroll KL, Rauchman M., J Biol Chem. November 30, 2007; 282 (48): 34858-68.                

Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system., Takahashi M, Osumi N., BMC Dev Biol. June 23, 2008; 8 87.                

xArx2: an aristaless homolog that regulates brain regionalization during development in Xenopus laevis., Wolanski M, Khosrowshahian F, Kelly LE, El-Hodiri HM, Crawford MJ., Genesis. January 1, 2009; 47 (1): 19-31.              

Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal., Rhinn M, Lun K, Ahrendt R, Geffarth M, Brand M., Neural Dev. April 2, 2009; 4 12.              

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                

Xmc mediates Xctr1-independent morphogenesis in Xenopus laevis., Haremaki T, Weinstein DC., Dev Dyn. September 1, 2009; 238 (9): 2382-7.            

The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction., Li B, Kuriyama S, Moreno M, Mayor R., Development. October 1, 2009; 136 (19): 3267-78.            

Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis., Klymkowsky MW, Rossi CC, Artinger KB., Cell Adh Migr. January 1, 2010; 4 (4): 595-608.  

The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    

Mesodermal Wnt signaling organizes the neural plate via Meis3., Elkouby YM, Elias S, Casey ES, Blythe SA, Tsabar N, Klein PS, Root H, Liu KJ, Liu KJ, Frank D., Development. May 1, 2010; 137 (9): 1531-41.        

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  

Toward an unbiased evolutionary platform for unraveling Xenopus developmental gene networks., Beer R, Wagner F, Grishkevich V, Peshkin L, Yanai I., Genesis. March 1, 2012; 50 (3): 186-91.        

Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions., Prasad MS, Sauka-Spengler T, LaBonne C., Dev Biol. June 1, 2012; 366 (1): 10-21.

Time space translation: a hox mechanism for vertebrate a-p patterning., Durston A, Wacker S, Bardine N, Jansen H., Curr Genomics. June 1, 2012; 13 (4): 300-7.          

Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning., Steventon B, Mayor R, Streit A., Dev Biol. July 1, 2012; 367 (1): 55-65.                

Signaling and transcriptional regulation in neural crest specification and migration: lessons from xenopus embryos., Pegoraro C, Monsoro-Burq AH., Wiley Interdiscip Rev Dev Biol. January 1, 2013; 2 (2): 247-59.      

Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning., Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H., J Biol Chem. November 1, 2013; 288 (44): 31477-87.                    

Identification of Pax3 and Zic1 targets in the developing neural crest., Bae CJ, Park BY, Lee YH, Lee YH, Tobias JW, Hong CS, Saint-Jeannet JP., Dev Biol. February 15, 2014; 386 (2): 473-83.                  

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers., Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH., Dev Biol. February 15, 2014; 386 (2): 461-72.                                            

Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                

Sp8 regulates inner ear development., Chung HA, Medina-Ruiz S, Harland RM., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6329-34.                                                    

Heat shock 70-kDa protein 5 (Hspa5) is essential for pronephros formation by mediating retinoic acid signaling., Shi W, Xu G, Wang C, Wang C, Wang C, Sperber SM, Chen Y, Chen Y, Zhou Q, Deng Y, Zhao H., J Biol Chem. January 2, 2015; 290 (1): 577-89.                        

Prepatterning and patterning of the thalamus along embryonic development of Xenopus laevis., Bandín S, Morona R, González A., Front Neuroanat. February 3, 2015; 9 107.                                                    

Embryonic transcription is controlled by maternally defined chromatin state., Hontelez S, van Kruijsbergen I, Georgiou G, van Heeringen SJ, Bogdanovic O, Lister R, Veenstra GJC., Nat Commun. December 18, 2015; 6 10148.                

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

Gene expression analysis of developing cell groups in the pretectal region of Xenopus laevis., Morona R, Ferran JL, Puelles L, González A., J Comp Neurol. March 1, 2017; 525 (4): 715-752.                                            

Collinear Hox-Hox interactions are involved in patterning the vertebrate anteroposterior (A-P) axis., Zhu K, Spaink HP, Durston AJ., PLoS One. April 11, 2017; 12 (4): e0175287.                

Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation., Kjolby RAS, Harland RM., Dev Biol. June 15, 2017; 426 (2): 165-175.                                    

Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.                

Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo., Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M., Development. March 12, 2018; 145 (5):                             

Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis., Gere-Becker MB, Pommerenke C, Lingner T, Pieler T., Development. June 8, 2018; 145 (12):                                   

RARγ is required for mesodermal gene expression prior to gastrulation in Xenopus., Janesick A, Tang W, Shioda T, Blumberg B., Development. September 17, 2018; 145 (18):                           

The neural border: Induction, specification and maturation of the territory that generates neural crest cells., Pla P, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S36-S46.    

What are the roles of retinoids, other morphogens, and Hox genes in setting up the vertebrate body axis?, Durston AJ., Genesis. July 1, 2019; 57 (7-8): e23296.            

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs., Alwin Prem Anand A, Alvarez-Bolado G, Wizenmann A., Front Cell Dev Biol. January 1, 2020; 8 586158.  

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