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Summary Expression Phenotypes Gene Literature (36) GO Terms (7) Nucleotides (50) Proteins (29) Interactants (163) Wiki
XB--876705

Papers associated with smad6.2



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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling., Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P., Nature. October 9, 1997; 389 (6651): 631-5.

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor., Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A., Genes Dev. January 15, 1998; 12 (2): 186-97.          

Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis., Nakayama T, Gardner H, Berg LK, Christian JL., Genes Cells. June 1, 1998; 3 (6): 387-94.                

Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer., Casellas R, Brivanlou AH., Dev Biol. June 1, 1998; 198 (1): 1-12.                

A molecular basis for Smad specificity., Lagna G, Hemmati-Brivanlou A., Dev Dyn. March 1, 1999; 214 (3): 269-77.

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals., Christian JL, Nakayama T., Bioessays. May 1, 1999; 21 (5): 382-90.

A role for the homeobox gene Xvex-1 as part of the BMP-4 ventral signaling pathway., Shapira E, Marom K, Yelin R, Levy A, Fainsod A., Mech Dev. August 1, 1999; 86 (1-2): 99-111.            

Evidence for a role of Smad6 in chick cardiac development., Yamada M, Szendro PI, Prokscha A, Schwartz RJ, Eichele G., Dev Biol. November 1, 1999; 215 (1): 48-61.

Dissection of inhibitory Smad proteins: both N- and C-terminal domains are necessary for full activities of Xenopus Smad6 and Smad7., Nakayama T, Berg LK, Christian JL., Mech Dev. February 1, 2001; 100 (2): 251-62.

TGF-beta signalling pathways in early Xenopus development., Hill CS., Curr Opin Genet Dev. October 1, 2001; 11 (5): 533-40.    

Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor., Bell E, Muñoz-Sanjuán I, Altmann CR, Vonica A, Brivanlou AH., Development. April 1, 2003; 130 (7): 1381-9.    

Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling., Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho KW., Mech Dev. May 1, 2003; 120 (5): 629-37.  

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads., Murakami G, Watabe T, Takaoka K, Miyazono K, Imamura T., Mol Biol Cell. July 1, 2003; 14 (7): 2809-17.              

[The role of Smads and related transcription factors in the signal transduction of bone morphogenetic protein inducing bone formation]., Xu XL, Dai KR, Tang TT., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. September 1, 2003; 17 (5): 359-62.

Evidence for antagonism of BMP-4 signals by MAP kinase during Xenopus axis determination and neural specification., Sater AK, El-Hodiri HM, Goswami M, Alexander TB, Al-Sheikh O, Etkin LD, Akif Uzman J., Differentiation. September 1, 2003; 71 (7): 434-44.                

Primitive erythropoiesis is regulated by Smad-dependent signaling in postgastrulation mesoderm., Schmerer M, Evans T., Blood. November 1, 2003; 102 (9): 3196-205.

Poly(ADP-ribose) polymerase 1 interacts with OAZ and regulates BMP-target genes., Ku MC, Stewart S, Hata A., Biochem Biophys Res Commun. November 21, 2003; 311 (3): 702-7.

Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling., Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K., J Biol Chem. July 23, 2004; 279 (30): 31568-74.

A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways., Zuzarte-Luís V, Montero JA, Rodriguez-León J, Merino R, Rodríguez-Rey JC, Hurlé JM., Dev Biol. August 1, 2004; 272 (1): 39-52.

Neural induction requires BMP inhibition only as a late step, and involves signals other than FGF and Wnt antagonists., Linker C, Stern CD., Development. November 1, 2004; 131 (22): 5671-81.      

Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition., Delaune E, Lemaire P, Kodjabachian L., Development. January 1, 2005; 132 (2): 299-310.                    

Temporal analysis of the early BMP functions identifies distinct anti-organizer and mesoderm patterning phases., Marom K, Levy V, Pillemer G, Fainsod A., Dev Biol. June 15, 2005; 282 (2): 442-54.              

XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos., Cao Y, Cao Y, Knöchel S, Oswald F, Donow C, Zhao H, Knöchel W., Mech Dev. January 1, 2006; 123 (1): 84-96.      

Smads oppose Hox transcriptional activities., Li X, Nie S, Chang C, Qiu T, Cao X., Exp Cell Res. April 1, 2006; 312 (6): 854-64.

Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway., Alexandrova EM, Thomsen GH., Dev Biol. November 15, 2006; 299 (2): 398-410.                      

Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation., Chang C, Harland RM., Development. November 1, 2007; 134 (21): 3861-72.                

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Cell communication with the neural plate is required for induction of neural markers by BMP inhibition: evidence for homeogenetic induction and implications for Xenopus animal cap and chick explant assays., Linker C, De Almeida I, Papanayotou C, Stower M, Sabado V, Ghorani E, Streit A, Mayor R, Stern CD., Dev Biol. March 15, 2009; 327 (2): 478-86.      

Expression cloning of Xenopus zygote arrest 2 (Xzar2) as a novel epidermalization-promoting factor in early embryos of Xenopus laevis., Nakajima Y, Okamoto H, Kubo T, Kubo T., Genes Cells. May 1, 2009; 14 (5): 583-95.                    

Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development., Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C., Proc Natl Acad Sci U S A. June 21, 2011; 108 (25): 10202-7.      

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling., Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP., Open Biol. May 1, 2014; 4 (5): 140065.              

Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos., Green YS, Kwon S, Mimoto MS, Xie Y, Christian JL., Development. November 1, 2016; 143 (21): 4016-4026.                            

Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14., Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A., Dev Growth Differ. April 1, 2018; 60 (3): 158-173.          

The Multifaceted Roles of USP15 in Signal Transduction., Das T, Song EJ, Kim EE., Int J Mol Sci. April 29, 2021; 22 (9):       

Patterning of the Vertebrate Head in Time and Space by BMP Signaling., Zhu K, Spaink HP, Durston AJ., J Dev Biol. July 3, 2023; 11 (3):         

FGFR1 variants contributed to families with tooth agenesis., Yao S, Zhou X, Gu M, Zhang C, Bartsch O, Vona B, Fan L, Ma L, Pan Y., Hum Genomics. October 13, 2023; 17 (1): 93.            

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