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Biochemical evidence that the whole compartment activity behavior of GAPDH differs between the cytoplasm and nucleus. , Tang HS, Gates CR, Schultz MC., PLoS One. January 1, 2023; 18 (8): e0290892.
MiR-9 and the Midbrain- Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs. , Alwin Prem Anand A, Alvarez-Bolado G, Wizenmann A., Front Cell Dev Biol. January 1, 2020; 8 586158.
Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney. , Zhang B, Tran U , Wessely O ., Development. March 22, 2018; 145 (6):
A quantitative hypermorphic CNGC allele confers ectopic calcium flux and impairs cellular development. , Chiasson DM, Haage K, Sollweck K, Brachmann A, Dietrich P, Parniske M., Elife. September 21, 2017; 6
Quantitative comparative analysis of the nasal chemosensory organs of anurans during larval development and metamorphosis highlights the relative importance of chemosensory subsystems in the group. , Jungblut LD, Reiss JO, Paz DA, Pozzi AG., J Morphol. September 1, 2017; 278 (9): 1208-1219.
Xenopus genomic data and browser resources. , Vize PD , Zorn AM ., Dev Biol. June 15, 2017; 426 (2): 194-199.
Gene Expression Profiling in the Injured Spinal Cord of Trachemys scripta elegans: An Amniote with Self-Repair Capabilities. , Valentin-Kahan A, García-Tejedor GB, Robello C, Trujillo-Cenóz O, Russo RE, Alvarez-Valin F., Front Mol Neurosci. February 7, 2017; 10 17.
Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels. , Wu W, Gardner A, Sachse FB, Sanguinetti MC., Mol Pharmacol. October 1, 2016; 90 (4): 469-82.
Mitragynine and its potential blocking effects on specific cardiac potassium channels. , Tay YL, Teah YF, Chong YM, Jamil MFA, Kollert S, Adenan MI, Wahab HA, Döring F, Wischmeyer E, Tan ML., Toxicol Appl Pharmacol. August 15, 2016; 305 22-39.
Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. , Owens ND, Blitz IL , Lane MA, Patrushev I , Overton JD, Gilchrist MJ , Cho KW , Khokha MK ., Cell Rep. January 26, 2016; 14 (3): 632-47.
Plant Aquaporins: Genome-Wide Identification, Transcriptomics, Proteomics, and Advanced Analytical Tools. , Deshmukh RK, Sonah H, Bélanger RR., Front Plant Sci. January 1, 2016; 7 1896.
HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana. , Du K, De Mieri M, Saxena P, Phungula KV, Wilhelm A, Hrubaru MM, van Rensburg E, Zietsman PC, Hering S, van der Westhuizen JH, Hamburger M., Planta Med. August 1, 2015; 81 (12-13): 1154-62.
C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation. , Gardner A, Sanguinetti MC., Mol Pharmacol. July 1, 2015; 88 (1): 19-28.
Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome. , Henriques C, Miller MP, Catanho M, de Carvalho TM, Krieger MA, Probst CM, de Souza W, Degrave W, Amara SG., Parasit Vectors. June 25, 2015; 8 346.
Human Ether-à- go-go Related Gene ( hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. , Grienke U, Mair CE, Saxena P, Baburin I, Scheel O, Ganzera M, Schuster D, Hering S, Rollinger JM., J Agric Food Chem. June 17, 2015; 63 (23): 5634-9.
The Link between Inactivation and High-Affinity Block of hERG1 Channels. , Wu W, Gardner A, Sanguinetti MC., Mol Pharmacol. June 1, 2015; 87 (6): 1042-50.
Identification and Bioinformatics Analyses of the Basic Helix-loop-helix Transcription Factors in Xenopus laevis. , Liu W, Li F., Pak J Biol Sci. April 1, 2015; 18 (4): 149-65.
Functional interaction of nicotinic acetylcholine receptors and Na+/K+ ATPase from Locusta migratoria manilensis (Meyen). , Bao H, Sun H, Xiao Y, Zhang Y , Zhang Y , Wang X , Xu X, Liu Z, Fang J, Li Z., Sci Rep. March 6, 2015; 5 8849.
Anesthetic drug midazolam inhibits cardiac human ether-à- go-go-related gene channels: mode of action. , Vonderlin N, Fischer F, Zitron E, Seyler C, Scherer D, Thomas D, Katus HA, Scholz EP., Drug Des Devel Ther. February 16, 2015; 9 867-77.
Ether-à- go-go family voltage-gated K+ channels evolved in an ancestral metazoan and functionally diversified in a cnidarian-bilaterian ancestor. , Li X, Martinson AS, Layden MJ, Diatta FH, Sberna AP, Simmons DK, Martindale MQ, Jegla TJ., J Exp Biol. February 15, 2015; 218 (Pt 4): 526-36.
Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243. , Wu W, Gardner A, Sanguinetti MC., Mol Pharmacol. January 1, 2015; 87 (3): 401-9.
Spatial trigger waves: positive feedback gets you a long way. , Gelens L, Anderson GA, Ferrell JE ., Mol Biol Cell. November 5, 2014; 25 (22): 3486-93.
Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs. , Smits AH, Lindeboom RG, Perino M, van Heeringen SJ, Veenstra GJ , Vermeulen M., Nucleic Acids Res. September 1, 2014; 42 (15): 9880-91.
Concerted all-or-none subunit interactions mediate slow deactivation of human ether-à- go-go-related gene K+ channels. , Thomson SJ, Hansen A, Sanguinetti MC., J Biol Chem. August 22, 2014; 289 (34): 23428-36.
Natural products as potential human ether-a- go-go-related gene channel inhibitors - outcomes from a screening of widely used herbal medicines and edible plants. , Schramm A, Jähne EA, Baburin I, Hering S, Hamburger M., Planta Med. August 1, 2014; 80 (12): 1045-50.
A tri-component conservation strategy reveals highly confident microRNA-mRNA interactions and evolution of microRNA regulatory networks. , Lin CC, Mitra R, Zhao Z., PLoS One. July 1, 2014; 9 (7): e103142.
Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion. , Ebert AM, Childs SJ, Hehr CL , Cechmanek PB, McFarlane S ., Development. June 1, 2014; 141 (12): 2473-82.
Natural products as potential human ether-a- go-go-related gene channel inhibitors - screening of plant-derived alkaloids. , Schramm A, Saxena P, Chlebek J, Cahlíková L, Baburin I, Hering S, Hamburger M., Planta Med. June 1, 2014; 80 (8-9): 740-6.
Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr. , Martinson AS, van Rossum DB, Diatta FH, Layden MJ, Rhodes SA, Martindale MQ, Jegla T., Proc Natl Acad Sci U S A. April 15, 2014; 111 (15): 5712-7.
Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. , Thouta S, Sokolov S, Abe Y, Clark SJ, Cheng YM, Claydon TW., Biophys J. March 4, 2014; 106 (5): 1057-69.
Up-regulation of hERG K⁺ channels by B-RAF. , Pakladok T, Hosseinzadeh Z, Almilaji A, Lebedeva A, Shumilina E, Alesutan I, Lang F ., PLoS One. January 1, 2014; 9 (1): e87457.
AMP-activated protein kinase regulates hERG potassium channel. , Almilaji A, Munoz C, Elvira B, Fajol A, Pakladok T, Honisch S, Shumilina E, Lang F , Föller M., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.
Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel. , Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.
Blockade of the human ether-a- go-go-related gene potassium channel by ketamine. , Zhang P, Xing J, Luo A, Feng J, Liu Z, Gao C, Ma J., J Pharm Pharmacol. September 1, 2013; 65 (9): 1321-8.
Exotic models may offer unique opportunities to decipher specific scientific question: the case of Xenopus olfactory system. , Gascuel J , Amano T ., Anat Rec (Hoboken). September 1, 2013; 296 (9): 1453-61.
Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels. , Cheng YM, Hull CM, Niven CM, Qi J, Allard CR, Claydon TW., J Gen Physiol. September 1, 2013; 142 (3): 289-303.
Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels. , Perry MD , Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.
The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium. , Dou Y, Goodchild SJ, Velde RV, Wu Y, Fedida D., Am J Physiol Cell Physiol. August 15, 2013; 305 (4): C468-78.
External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor. , Kazmierczak M, Zhang X, Chen B, Mulkey DK, Shi Y , Wagner PG, Pivaroff-Ward K, Sassic JK, Bayliss DA, Jegla T., J Gen Physiol. June 1, 2013; 141 (6): 721-35.
Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels. , de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F., Biochem J. May 1, 2013; 451 (3): 463-74.
ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels. , Garg V, Stary-Weinzinger A, Sanguinetti MC., Mol Pharmacol. April 1, 2013; 83 (4): 805-13.
Flavonoid regulation of EAG1 channels. , Carlson AE, Brelidze TI, Zagotta WN., J Gen Physiol. March 1, 2013; 141 (3): 347-58.
Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration. , Hong HK, Lee BH, Park MH, Lee SH, Chu D, Kim WJ, Choe H, Hee Choi B, Jo SH., Eur J Pharmacol. February 28, 2013; 702 (1-3): 165-73.
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. , Long HK, Sims D , Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R , Ponting CP, Klose RJ., Elife. February 26, 2013; 2 e00348.
The eag domain regulates hERG channel inactivation gating via a direct interaction. , Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.
Serotonin has early, cilia-independent roles in Xenopus left- right patterning. , Vandenberg LN, Lemire JM , Levin M ., Dis Model Mech. January 1, 2013; 6 (1): 261-8.
Blocking of the human ether-à- go-go-related gene channel by imatinib mesylate. , Dong Q, Fu XX, Du LL, Zhao N, Xia CK, Yu KW, Cheng LX, Du YM., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.
[Follicular cells of the amphibian ovary: origin, structure, and functions]. , Konduktorova VV, Luchinskaia NN., Ontogenez. January 1, 2013; 44 (5): 316-30.
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins. , Peigneur S, Béress L, Möller C, Marí F, Forssmann WG, Tytgat J., FASEB J. December 1, 2012; 26 (12): 5141-51.
Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule. , Garg V, Sachse FB, Sanguinetti MC., J Gen Physiol. September 1, 2012; 140 (3): 307-24.