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Summary Expression Phenotypes Gene Literature (53) GO Terms (5) Nucleotides (287) Proteins (75) Interactants (457) Wiki
XB-GENEPAGE-941406

Papers associated with pxn



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Localization of paxillin, a focal adhesion protein, to smooth muscle dense plaques, and the myotendinous and neuromuscular junctions of skeletal muscle., Turner CE, Kramarcy N, Sealock R, Burridge K., Exp Cell Res. February 1, 1991; 192 (2): 651-5.

Paxillin binding to a conserved sequence motif in the alpha 4 integrin cytoplasmic domain., Liu S, Ginsberg MH., J Biol Chem. July 28, 2000; 275 (30): 22736-42.

Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins., Honda S, Kashiwagi M, Miyamoto K, Takei Y, Hirose S., J Biol Chem. October 20, 2000; 275 (42): 33151-7.    

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II., Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB., Oncogene. February 22, 2001; 20 (8): 951-61.

mRNA sequence of the Xenopus laevis paxillin gene and its expression., Ogawa M, Hiraoka Y, Taniguchi K, Sakai Y, Aiso S., Biochim Biophys Acta. June 28, 2001; 1519 (3): 235-40.

Expression patterns of focal adhesion associated proteins in the developing retina., Li M, Sakaguchi DS., Dev Dyn. December 1, 2002; 225 (4): 544-53.                

Nuclear translocation of Xenopus laevis paxillin., Ogawa M, Hiraoka Y, Aiso S., Biochem Biophys Res Commun. May 16, 2003; 304 (4): 676-83.

A PTP-PEST-like protein affects alpha5beta1-integrin-dependent matrix assembly, cell adhesion, and migration in Xenopus gastrula., Cousin H, Alfandari D, Alfandari D., Dev Biol. January 15, 2004; 265 (2): 416-32.                  

Inhibition of integrin-mediated adhesion and signaling disrupts retinal development., Li M, Sakaguchi DS., Dev Biol. November 1, 2004; 275 (1): 202-14.

Cloning and developmental expression of Xenopus Enabled (Xena)., Xanthos JB, Wanner SJ, Miller JR., Dev Dyn. June 1, 2005; 233 (2): 631-7.      

Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts., Woo S, Gomez TM., J Neurosci. February 1, 2006; 26 (5): 1418-28.

Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop., Rasar M, DeFranco DB, Hammes SR., J Biol Chem. December 22, 2006; 281 (51): 39455-64.              

Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility., Iioka H, Iemura S, Natsume T, Kinoshita N., Nat Cell Biol. July 1, 2007; 9 (7): 813-21.

Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7., James BP, Bunch TA, Krishnamoorthy S, Perkins LA, Brower DL., Mol Biol Cell. October 1, 2007; 18 (10): 4190-9.

Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins., Tonge D, Chan K, Zhu N, Panjwani A, Arno M, Lynham S, Ward M, Snape A, Pizzey J., J Cell Sci. August 1, 2008; 121 (Pt 15): 2565-77.                        

Imaging morphogenesis, in Xenopus with Quantum Dot nanocrystals., Stylianou P, Skourides PA., Mech Dev. October 1, 2009; 126 (10): 828-41.          

Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells., Sen A, O'Malley K, Wang Z, Raj GV, Defranco DB, Hammes SR., J Biol Chem. September 10, 2010; 285 (37): 28787-95.

Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site., Thompson AJ, Jarvis GE, Duke RK, Johnston GA, Lummis SC., Neuropharmacology. January 1, 2011; 60 (2-3): 488-95.        

Binding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor., Thompson AJ, Duke RK, Lummis SC., Mol Pharmacol. July 1, 2011; 80 (1): 183-90.

Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating protein (Rho-GAP), GRAF1., Doherty JT, Lenhart KC, Cameron MV, Mack CP, Conlon FL, Taylor JM., J Biol Chem. July 22, 2011; 286 (29): 25903-21.                    

Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo., Charalambous A, Antoniades I, Christodoulou N, Skourides PA., J Nanobiotechnology. September 15, 2011; 9 37.              

Focal adhesion kinase promotes integrin adhesion dynamics necessary for chemotropic turning of nerve growth cones., Myers JP, Gomez TM., J Neurosci. September 21, 2011; 31 (38): 13585-95.

Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos., Petridou NI, Stylianou P, Christodoulou N, Rhoads D, Guan JL, Skourides PA., PLoS One. January 1, 2012; 7 (8): e42577.            

SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y, Tandon P, Paden E, Duddy J, Taylor JM, Conlon FL., Development. March 1, 2012; 139 (5): 948-57.                

Imaging adhesion and signaling dynamics in Xenopus laevis growth cones., Santiago-Medina M, Myers JP, Gomez TM., Dev Neurobiol. April 1, 2012; 72 (4): 585-99.          

The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization., Bonacci G, Fletcher J, Devani M, Dwivedi H, Keller R, Chang C., Dev Biol. April 1, 2012; 364 (1): 42-55.                                        

The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor., Thompson AJ, Alqazzaz M, Ulens C, Lummis SC., Neuropharmacology. September 1, 2012; 63 (4): 761-7.          

Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration., Fuentealba J, Toro-Tapia G, Arriagada C, Riquelme L, Beyer A, Henriquez JP, Caprile T, Mayor R, Marcellini S, Hinrichs MV, Olate J, Torrejón M., Dev Biol. June 15, 2013; 378 (2): 74-82.          

FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis., Petridou NI, Skourides PA., Nat Commun. January 1, 2014; 5 5240.      

In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity., Kuriyama S, Theveneau E, Benedetto A, Parsons M, Tanaka M, Charras G, Kabla A, Mayor R., J Cell Biol. July 7, 2014; 206 (1): 113-27.                                

Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor function., Thompson AJ, Alqazzaz M, Price KL, Weston DA, Lummis SC., Biochemistry. October 7, 2014; 53 (39): 6183-8.            

Regulation of ECM degradation and axon guidance by growth cone invadosomes., Santiago-Medina M, Gregus KA, Nichol RH, O'Toole SM, Gomez TM., Development. February 1, 2015; 142 (3): 486-96.                        

Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces., Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R., Dev Cell. August 24, 2015; 34 (4): 421-34.                                            

Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact Adhesions., Nichol RH, Hagen KM, Lumbard DC, Dent EW, Gómez TM., J Neurosci. February 17, 2016; 36 (7): 2267-82.

The Lhx9-integrin pathway is essential for positioning of the proepicardial organ., Tandon P, Wilczewski CM, Williams CE, Conlon FL., Development. March 1, 2016; 143 (5): 831-40.                                    

Cadherin-11 localizes to focal adhesions and promotes cell-substrate adhesion., Langhe RP, Gudzenko T, Bachmann M, Becker SF, Gonnermann C, Winter C, Abbruzzese G, Alfandari D, Alfandari D, Kratzer MC, Franz CM, Kashef J., Nat Commun. March 8, 2016; 7 10909.        

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis., Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM., Elife. September 13, 2016; 5                                   

Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells., Antoniades I, Stylianou P, Christodoulou N, Skourides PA., J Biol Chem. January 13, 2017; 292 (2): 488-504.              

Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance., Kerstein PC, Patel KM, Gomez TM., J Neurosci. February 8, 2017; 37 (6): 1568-1580.                

Paxillin and embryonic PolyAdenylation Binding Protein (ePABP) engage to regulate androgen-dependent Xenopus laevis oocyte maturation - A model of kinase-dependent regulation of protein expression., Miedlich SU, Taya M, Young MR, Hammes SR., Mol Cell Endocrinol. June 15, 2017; 448 87-97.

Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of Xenopus mesendoderm tissue at gastrulation., Sonavane PR, Wang C, Dzamba B, Weber GF, Periasamy A, DeSimone DW., Development. December 1, 2017; 144 (23): 4363-4376.                            

Redistribution of Adhesive Forces through Src/FAK Drives Contact Inhibition of Locomotion in Neural Crest., Roycroft A, Szabó A, Bahm I, Daly L, Charras G, Parsons M, Mayor R., Dev Cell. June 4, 2018; 45 (5): 565-579.e3.                                        

Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing., Shindo A, Audrey A, Takagishi M, Takahashi M, Wallingford JB, Kinoshita M., J Cell Sci. June 28, 2018; 131 (12):


The Ric-8A/Gα13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in Xenopus., Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M., Development. November 21, 2018; 145 (22):                               

In vivo topology converts competition for cell-matrix adhesion into directional migration., Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E., Nat Commun. April 3, 2019; 10 (1): 1518.                    

Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs., Chan ZC, Kwan HR, Wong YS, Jiang Z, Zhou Z, Tam KW, Chan YS, Chan CB, Lee CW, Lee CW., Elife. March 24, 2020; 9                                     

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility., Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F., PLoS Biol. January 6, 2021; 19 (1): e3001060.                                            

Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Rao VG, Kulkarni SS., Genesis. February 1, 2021; 59 (1-2): e23414.  

Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway., Wang H, Wang C, Wang C, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H., Development. May 15, 2021; 148 (10):                                           

The mechanosensitive channel Piezo1 cooperates with semaphorins to control neural crest migration., Canales Coutiño B, Mayor R., Development. December 1, 2021; 148 (23):                           

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