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Summary Expression Phenotypes Gene Literature (8) GO Terms (8) Nucleotides (430) Proteins (56) Interactants (160) Wiki
XB--950001

Papers associated with top1.1



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Synthesis and Biological Activity of a New Indenoisoquinoline Copper Derivative as a Topoisomerase I Inhibitor., Molinaro C, Wambang N, Pellegrini S, Henry N, Lensink MF, Germain E, Bousquet T, de Ruyck J, Cailliau K, Pélinski L, Martoriati A., Int J Mol Sci. September 26, 2023; 24 (19):               

Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing., Zhang Z, Zhang Z, Jones AE, Wu W, Kim J, Kang Y, Bi X, Gu Y, Popov IK, Renfrow MB, Vassylyeva MN, Vassylyev DG, Giles KE, Chen D, Kumar A, Fan Y, Tong Y, Liu CF, An W, Chang C, Luo J, Chow LT, Wang H., Proc Natl Acad Sci U S A. September 19, 2017; 114 (38): E7949-E7958.                          

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Topoisomerase I poisoning results in PARP-mediated replication fork reversal., Ray Chaudhuri A, Hashimoto Y, Herrador R, Neelsen KJ, Fachinetti D, Bermejo R, Cocito A, Costanzo V, Lopes M., Nat Struct Mol Biol. March 4, 2012; 19 (4): 417-23.

Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends., Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M, Onodera O., Nucleic Acids Res. January 1, 2007; 35 (11): 3797-809.                  

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1., El-Khamisy SF, Saifi GM, Weinfeld M, Johansson F, Helleday T, Lupski JR, Caldecott KW., Nature. March 3, 2005; 434 (7029): 108-13.

Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae., Castaño IB, Brzoska PM, Sadoff BU, Chen H, Christman MF., Genes Dev. October 15, 1996; 10 (20): 2564-76.

Localization of a high molecular weight form of DNA topoisomerase I in amphibian oocytes., Gebauer D, Mais C, Zinger K, Hock R, Lieb B, Scheer U., Int J Dev Biol. February 1, 1996; 40 (1): 239-44.      

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