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Summary Expression Phenotypes Gene Literature (15) GO Terms (8) Nucleotides (67) Proteins (40) Interactants (24) Wiki
XB-GENEPAGE-950561

Papers associated with kcnk10



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Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation., Schroeter CB, Nelke C, Schewe M, Spohler L, Herrmann AM, Müntefering T, Huntemann N, Kuzikov M, Gribbon P, Albrecht S, Bock S, Hundehege P, Neelsen LC, Baukrowitz T, Seebohm G, Wünsch B, Bittner S, Ruck T, Budde T, Meuth SG., Biol Chem. March 28, 2023; 404 (4): 355-375.              


Mechanistic insights into volatile anesthetic modulation of K2P channels., Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM., Elife. December 21, 2020; 9                   


TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons., Lengyel M, Czirják G, Jacobson DA, Enyedi P., J Biol Chem. August 28, 2020; 295 (35): 12408-12425.                      


Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK., Royal P, Andres-Bilbe A, Ávalos Prado P, Verkest C, Wdziekonski B, Schaub S, Baron A, Lesage F, Gasull X, Levitz J, Sandoz G., Neuron. January 16, 2019; 101 (2): 232-245.e6.


Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states., McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ., J Gen Physiol. June 1, 2016; 147 (6): 497-505.          


Differential sensitivity of TREK-1, TREK-2 and TRAAK background potassium channels to the polycationic dye ruthenium red., Braun G, Lengyel M, Enyedi P, Czirják G., Br J Pharmacol. April 1, 2015; 172 (7): 1728-38.


Vernakalant activates human cardiac K(2P)17.1 background K(+) channels., Seyler C, Schweizer PA, Zitron E, Katus HA, Thomas D., Biochem Biophys Res Commun. August 29, 2014; 451 (3): 415-20.


Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons., Schreiner BS, Lehmann R, Thiel U, Ziemba PM, Beltrán LR, Sherkheli MA, Jeanbourquin P, Hugi A, Werner M, Gisselmann G, Hatt H., Eur J Pharmacol. April 5, 2014; 728 48-58.


2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2)., Beltrán L, Beltrán M, Aguado A, Gisselmann G, Hatt H., Front Pharmacol. May 15, 2013; 4 63.      


The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK., Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H., Front Pharmacol. January 1, 2013; 4 141.              


Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels., Gierten J, Hassel D, Schweizer PA, Becker R, Katus HA, Thomas D., Biochim Biophys Acta. January 1, 2012; 1818 (1): 33-41.


Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue., Sandoz G, Douguet D, Chatelain F, Lazdunski M, Lesage F., Proc Natl Acad Sci U S A. August 25, 2009; 106 (34): 14628-33.


Properties of single two-pore domain TREK-2 channels expressed in mammalian cells., Kang D, Choe C, Cavanaugh E, Kim D., J Physiol. August 15, 2007; 583 (Pt 1): 57-69.


Zinc and mercuric ions distinguish TRESK from the other two-pore-domain K+ channels., Czirják G, Enyedi P., Mol Pharmacol. March 1, 2006; 69 (3): 1024-32.


Zinc activates TREK-2 potassium channel activity., Kim JS, Park JY, Kang HW, Lee EJ, Bang H, Lee JH, Lee JH., J Pharmacol Exp Ther. August 1, 2005; 314 (2): 618-25.

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