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Summary Expression Gene Literature (38) GO Terms (7) Nucleotides (38) Proteins (17) Interactants (33) Wiki

Papers associated with kcnk2

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Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel., Fink M, Duprat F, Lesage F, Reyes R, Romey G, Heurteaux C, Lazdunski M., EMBO J. December 16, 1996; 15 (24): 6854-62.

An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum., Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, Chavez RA, Forsayeth JR, Yost CS., J Neurosci. February 1, 1998; 18 (3): 868-77.

A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids., Fink M, Lesage F, Duprat F, Heurteaux C, Reyes R, Fosset M, Lazdunski M., EMBO J. June 15, 1998; 17 (12): 3297-308.

Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel., Meadows HJ, Benham CD, Cairns W, Gloger I, Jennings C, Medhurst AD, Murdock P, Chapman CG., Pflugers Arch. April 1, 2000; 439 (6): 714-22.

TREK-1 is a heat-activated background K(+) channel., Maingret F, Lauritzen I, Patel AJ, Heurteaux C, Reyes R, Lesage F, Lazdunski M, Honoré E., EMBO J. June 1, 2000; 19 (11): 2483-91.

The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK., Meadows HJ, Chapman CG, Duckworth DM, Kelsell RE, Murdock PR, Nasir S, Rennie G, Randall AD., Dev Biol. February 16, 2001; 892 (1): 94-101.

KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel., Bockenhauer D, Zilberberg N, Goldstein SA., Nat Neurosci. May 1, 2001; 4 (5): 486-91.

A plant Shaker-like K+ channel switches between two distinct gating modes resulting in either inward-rectifying or "leak" current., Dreyer I, Michard E, Lacombe B, Thibaud JB., FEBS Lett. September 14, 2001; 505 (2): 233-9.

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels., Lopes CM, Rohács T, Czirják G, Balla T, Enyedi P, Logothetis DE., J Physiol. April 1, 2005; 564 (Pt 1): 117-29.

Zinc and mercuric ions distinguish TRESK from the other two-pore-domain K+ channels., Czirják G, Enyedi P., Mol Pharmacol. March 1, 2006; 69 (3): 1024-32.

AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels., Sandoz G, Thümmler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F., EMBO J. December 13, 2006; 25 (24): 5864-72.

Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1., Putzke C, Hanley PJ, Schlichthörl G, Preisig-Müller R, Rinné S, Anetseder M, Eckenhoff R, Berkowitz C, Vassiliou T, Wulf H, Eberhart L., Am J Physiol Cell Physiol. October 1, 2007; 293 (4): C1319-26.

Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium., Thomas D, Plant LD, Wilkens CM, McCrossan ZA, Goldstein SA., Neuron. June 26, 2008; 58 (6): 859-70.

A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues., Cohen A, Ben-Abu Y, Hen S, Zilberberg N., J Biol Chem. July 11, 2008; 283 (28): 19448-55.

Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking., Sandoz G, Tardy MP, Thümmler S, Feliciangeli S, Lazdunski M, Lesage F., J Neurosci. August 20, 2008; 28 (34): 8545-52.

Pain-associated signals, acidosis and lysophosphatidic acid, modulate the neuronal K(2P)2.1 channel., Cohen A, Sagron R, Somech E, Segal-Hayoun Y, Zilberberg N., Mol Cell Neurosci. March 1, 2009; 40 (3): 382-9.

TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices., Zhou M, Xu G, Xie M, Zhang X, Schools GP, Ma L, Kimelberg HK, Chen H., J Neurosci. July 1, 2009; 29 (26): 8551-64.

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue., Sandoz G, Douguet D, Chatelain F, Lazdunski M, Lesage F., Proc Natl Acad Sci U S A. August 25, 2009; 106 (34): 14628-33.

Molecular mechanisms underlying membrane-potential-mediated regulation of neuronal K2P2.1 channels., Segal-Hayoun Y, Cohen A, Zilberberg N., Mol Cell Neurosci. January 1, 2010; 43 (1): 117-26.

Optical probing of a dynamic membrane interaction that regulates the TREK1 channel., Sandoz G, Bell SC, Isacoff EY., Proc Natl Acad Sci U S A. February 8, 2011; 108 (6): 2605-10.

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