Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (100) GO Terms (0) Nucleotides (22) Proteins (12) Interactants (102) Wiki
XB-GENEPAGE-956080

Papers associated with kcnk3



???displayGene.coCitedPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

MicroRNAs Regulate TASK-1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation., Wiedmann F, Kraft M, Kallenberger S, Büscher A, Paasche A, Blochberger PL, Seeger T, Jávorszky N, Warnecke G, Arif R, Kremer J, Karck M, Frey N, Schmidt C., J Am Heart Assoc. April 5, 2022; 11 (7): e023472.


Genetic and Physiological Effects of Insulin on Human Urate Homeostasis., Mandal AK, Leask MP, Estiverne C, Choi HK, Merriman TR, Mount DB., Front Physiol. January 1, 2021; 12 713710.              


Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine., Lee SH, Lee HS, Park G, Oh SM, Oh DS., BMC Complement Altern Med. March 12, 2019; 19 (1): 57.        


Inhibitory effects of Kampo medicines, Keishibukuryogan and Shakuyakukanzoto, on the substrate uptake activities of solute carrier organic anion transporters., Lee HS, Shin HJ, Cho M, Lee SH, Oh DS., J Pharmacol Sci. December 1, 2018; 138 (4): 279-283.


Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux., Lofthouse EM, Cleal JK, O'Kelly IM, Sengers BG, Lewis RM., Biochem Biophys Res Commun. November 17, 2018; 506 (1): 237-242.          


Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess., Ohashi A, Mamada K, Harada T, Naito M, Takahashi T, Aizawa S, Hasegawa H., Mol Cell Biochem. November 1, 2017; 435 (1-2): 97-108.        


The Effect of Pungent and Tingling Compounds from Piper nigrum L. on Background K+ Currents., Beltrán LR, Dawid C, Beltrán M, Levermann J, Titt S, Thomas S, Pürschel V, Satalik M, Gisselmann G, Hofmann T, Hatt H., Front Pharmacol. May 26, 2017; 8 408.                


Roles of organic anion transporters (OATs) in renal proximal tubules and their localization., Otani N, Ouchi M, Hayashi K, Jutabha P, Anzai N., Anat Sci Int. March 1, 2017; 92 (2): 200-206.


Uricosuric targets of tranilast., Mandal AK, Mercado A, Foster A, Zandi-Nejad K, Mount DB., Pharmacol Res Perspect. February 6, 2017; 5 (2): e00291.                    


Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis., Telles CJ, Decker SE, Motley WW, Peters AW, Mehr AP, Frizzell RA, Forrest JN., Am J Physiol Cell Physiol. December 1, 2016; 311 (6): C884-C894.


The Possible Role of TASK Channels in Rank-Ordered Recruitment of Motoneurons in the Dorsolateral Part of the Trigeminal Motor Nucleus., Okamoto K, Emura N, Sato H, Fukatsu Y, Saito M, Tanaka C, Morita Y, Nishimura K, Kuramoto E, Xu Yin D, Furutani K, Okazawa M, Kurachi Y, Kaneko T, Maeda Y, Yamashiro T, Takada K, Toyoda H, Kang Y., eNeuro. July 20, 2016; 3 (3):                     


Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?, Kiper AK, Rinné S, Rolfes C, Ramírez D, Seebohm G, Netter MF, González W, Decher N., Pflugers Arch. May 1, 2015; 467 (5): 1081-90.


Differential sensitivity of TREK-1, TREK-2 and TRAAK background potassium channels to the polycationic dye ruthenium red., Braun G, Lengyel M, Enyedi P, Czirják G., Br J Pharmacol. April 1, 2015; 172 (7): 1728-38.


Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9., Kubota K, Ohtake N, Ohbuchi K, Mase A, Imamura S, Sudo Y, Miyano K, Yamamoto M, Kono T, Uezono Y., Am J Physiol Gastrointest Liver Physiol. April 1, 2015; 308 (7): G579-90.                  


TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes., Rinné S, Kiper AK, Schlichthörl G, Dittmann S, Netter MF, Limberg SH, Silbernagel N, Zuzarte M, Moosdorf R, Wulf H, Schulze-Bahr E, Rolfes C, Decher N., J Mol Cell Cardiol. April 1, 2015; 81 71-80.


Transporters involved in renal excretion of N-carbamoylglutamate, an orphan drug to treat inborn n-acetylglutamate synthase deficiency., Schwob E, Hagos Y, Burckhardt G, Burckhardt BC., Am J Physiol Renal Physiol. December 15, 2014; 307 (12): F1373-9.


Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure., Schmidt C, Wiedmann F, Langer C, Tristram F, Anand P, Wenzel W, Lugenbiel P, Schweizer PA, Katus HA, Thomas D., Heart Rhythm. October 1, 2014; 11 (10): 1798-805.


Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder., Friedrich C, Rinné S, Zumhagen S, Kiper AK, Silbernagel N, Netter MF, Stallmeyer B, Schulze-Bahr E, Decher N., EMBO Mol Med. July 1, 2014; 6 (7): 937-51.              


Cooperative endocytosis of the endosomal SNARE protein syntaxin-8 and the potassium channel TASK-1., Renigunta V, Fischer T, Zuzarte M, Kling S, Zou X, Siebert K, Limberg MM, Rinné S, Decher N, Schlichthörl G, Daut J., Mol Biol Cell. June 15, 2014; 25 (12): 1877-91.                


Novel TASK channels inhibitors derived from dihydropyrrolo[2,1-a]isoquinoline., Noriega-Navarro R, Lopez-Charcas O, Hernández-Enríquez B, Reyes-Gutiérrez PE, Martínez R, Landa A, Morán J, Gomora JC, Garcia-Valdes J., Neuropharmacology. April 1, 2014; 79 28-36.


Inhibition of cardiac two-pore-domain K+ (K2P) channels by the antiarrhythmic drug vernakalant--comparison with flecainide., Seyler C, Li J, Schweizer PA, Katus HA, Thomas D., Eur J Pharmacol. February 5, 2014; 724 51-7.


Diuresis by intravenous administration of xanthurenic acid in rats, and inhibition by probenecid., Uwai Y, Nakashima Y, Honjo E, Kawasaki T, Nabekura T., Biomed Res. January 1, 2014; 35 (3): 223-6.


Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels., Schmidt C, Wiedmann F, Schweizer PA, Becker R, Katus HA, Thomas D., Eur J Pharmacol. December 5, 2013; 721 (1-3): 237-48.


Transient receptor potential channels encode volatile chemicals sensed by rat trigeminal ganglion neurons., Lübbert M, Kyereme J, Schöbel N, Beltrán L, Wetzel CH, Hatt H., PLoS One. October 8, 2013; 8 (10): e77998.                


Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1., Uwai Y, Hara H, Iwamoto K., Int J Tryptophan Res. January 1, 2013; 6 1-6.      


The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK., Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H., Front Pharmacol. January 1, 2013; 4 141.              


Caffeic acid inhibits organic anion transporters OAT1 and OAT3 in rat kidney., Uwai Y, Kawasaki T, Nabekura T., Drug Metabol Drug Interact. January 1, 2013; 28 (4): 247-50.


Transport of xanthurenic acid by rat/human organic anion transporters OAT1 and OAT3., Uwai Y, Honjo E., Biosci Biotechnol Biochem. January 1, 2013; 77 (7): 1517-21.


Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin., Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS., J Clin Pharmacol. January 1, 2013; 53 (1): 75-81.


A role for the organic anion transporter OAT3 in renal creatinine secretion in mice., Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T., Am J Physiol Renal Physiol. May 15, 2012; 302 (10): F1293-9.


TASK1 (K(2P)3.1) K(+) channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylation., Seyler C, Duthil-Straub E, Zitron E, Gierten J, Scholz EP, Fink RH, Karle CA, Becker R, Katus HA, Thomas D., Br J Pharmacol. March 1, 2012; 165 (5): 1467-75.


The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization., Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H., J Biol Chem. October 28, 2011; 286 (43): 37874-86.


Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis., Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK., J Biol Chem. September 9, 2011; 286 (36): 31522-31.


Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels., Staudacher K, Staudacher I, Ficker E, Seyler C, Gierten J, Kisselbach J, Rahm AK, Trappe K, Schweizer PA, Becker R, Katus HA, Thomas D., Br J Pharmacol. July 1, 2011; 163 (5): 1099-110.


Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1)., Wikoff WR, Nagle MA, Kouznetsova VL, Tsigelny IF, Nigam SK., J Proteome Res. June 3, 2011; 10 (6): 2842-51.


In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate., Elsby R, Fox L, Stresser D, Layton M, Butters C, Sharma P, Smith V, Surry D., Eur J Pharm Sci. May 18, 2011; 43 (1-2): 41-9.


A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore., Streit AK, Netter MF, Kempf F, Walecki M, Rinné S, Bollepalli MK, Preisig-Müller R, Renigunta V, Daut J, Baukrowitz T, Sansom MS, Stansfeld PJ, Decher N., J Biol Chem. April 22, 2011; 286 (16): 13977-84.                


Protein kinase A is central for forward transport of two-pore domain potassium channels K2P3.1 and K2P9.1., Mant A, Elliott D, Eyers PA, O'Kelly IM., J Biol Chem. April 22, 2011; 286 (16): 14110-9.


The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons., Brauburger K, Burckhardt G, Burckhardt BC., J Inherit Metab Dis. April 1, 2011; 34 (2): 477-82.      


Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions., Choi MK, Jin QR, Choi YL, Ahn SH, Bae MA, Song IS., Biopharm Drug Dispos. April 1, 2011; 32 (3): 175-84.


Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling., Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, Nigam SK., J Biol Chem. January 7, 2011; 286 (1): 243-51.


TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes., Limberg SH, Netter MF, Rolfes C, Rinné S, Schlichthörl G, Zuzarte M, Vassiliou T, Moosdorf R, Wulf H, Daut J, Sachse FB, Decher N., Cell Physiol Biochem. January 1, 2011; 28 (4): 613-24.


Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate., Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H., J Biol Chem. November 5, 2010; 285 (45): 35123-32.


The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone., Gierten J, Ficker E, Bloehs R, Schweizer PA, Zitron E, Scholz E, Karle C, Katus HA, Thomas D., Naunyn Schmiedebergs Arch Pharmacol. March 1, 2010; 381 (3): 261-70.


Interaction of organic cations with organic anion transporters., Ahn SY, Eraly SA, Tsigelny I, Nigam SK., J Biol Chem. November 6, 2009; 284 (45): 31422-30.


Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy., Bakhiya N, Arlt VM, Bahn A, Burckhardt G, Phillips DH, Glatt H., Toxicology. October 1, 2009; 264 (1-2): 74-9.


Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins., Zuzarte M, Heusser K, Renigunta V, Schlichthörl G, Rinné S, Wischmeyer E, Daut J, Schwappach B, Preisig-Müller R., J Physiol. March 1, 2009; 587 (Pt 5): 929-52.


Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias., Hagos Y, Krick W, Braulke T, Mühlhausen C, Burckhardt G, Burckhardt BC., Pflugers Arch. October 1, 2008; 457 (1): 223-31.


Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics., Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK., Am J Physiol Renal Physiol. April 1, 2008; 294 (4): F867-73.


Forward Transport of K2p3.1: mediation by 14-3-3 and COPI, modulation by p11., O'Kelly I, Goldstein SA., Traffic. January 1, 2008; 9 (1): 72-8.

???pagination.result.page??? 1 2 ???pagination.result.next???