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Summary Expression Phenotypes Gene Literature (67) GO Terms (5) Nucleotides (637) Proteins (43) Interactants (593) Wiki
XB-GENEPAGE-961587

Papers associated with has1



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Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm., Luu O, Barua D, Winklbauer R., PLoS One. January 1, 2024; 19 (2): e0297420.                  


A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development., Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN., Sci Adv. April 7, 2023; 9 (14): eadd5745.                                                          


Cell-cell contact landscapes in Xenopus gastrula tissues., Barua D, Nagel M, Winklbauer R., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                           


Expression of hyaluronan synthases upregulated by thyroid hormone is involved in intestinal stem cell development during Xenopus laevis metamorphosis., Fujimoto K, Hasebe T, Kajita M, Ishizuya-Oka A., Dev Genes Evol. December 1, 2018; 228 (6): 267-273.


G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          


Hyaluronan is required for cranial neural crest cells migration and craniofacial development., Casini P, Nardi I, Ori M., Dev Dyn. February 1, 2012; 241 (2): 294-302.              


Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles., Contreras EG, Gaete M, Sánchez N, Carrasco H, Larraín J., Development. September 1, 2009; 136 (17): 2987-96.                    


XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms., van Grunsven LA, Taelman V, Michiels C, Verstappen G, Souopgui J, Nichane M, Moens E, Opdecamp K, Vanhomwegen J, Kricha S, Huylebroeck D, Bellefroid EJ., Dev Biol. June 1, 2007; 306 (1): 34-49.            


Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis., Chalmers AD, Lachani K, Shin Y, Sherwood V, Cho KW, Papalopulu N., Mech Dev. September 1, 2006; 123 (9): 702-18.                                                  


XHas2 activity is required during somitogenesis and precursor cell migration in Xenopus development., Ori M, Nardini M, Casini P, Perris R, Nardi I., Development. February 1, 2006; 133 (4): 631-40.                        


An atlas of differential gene expression during early Xenopus embryogenesis., Pollet N, Muncke N, Verbeek B, Li Y, Fenger U, Delius H, Niehrs C., Mech Dev. March 1, 2005; 122 (3): 365-439.                                                                                                                                                        


Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Pera EM, Hou S, Strate I, Wessely O, De Robertis EM., Int J Dev Biol. January 1, 2005; 49 (7): 781-96.                                  


Regulated gene expression of hyaluronan synthases during Xenopus laevis development., Nardini M, Ori M, Vigetti D, Gornati R, Nardi I, Perris R., Gene Expr Patterns. May 1, 2004; 4 (3): 303-8.        


Molecular cloning, genomic organization and developmental expression of the Xenopus laevis hyaluronan synthase 3., Vigetti D, Viola M, Gornati R, Ori M, Nardi I, Passi A, De Luca G, Bernardini G., Matrix Biol. November 1, 2003; 22 (6): 511-7.  


The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers., Monslow J, Williams JD, Norton N, Guy CA, Price IK, Coleman SL, Williams NM, Buckland PR, Spicer AP, Topley N, Davies M, Bowen T., Int J Biochem Cell Biol. August 1, 2003; 35 (8): 1272-83.


Expression of hyaluronan synthases and corresponding hyaluronan receptors is differentially regulated during oocyte maturation in cattle., Schoenfelder M, Einspanier R., Biol Reprod. July 1, 2003; 69 (1): 269-77.


Abnormal expression of hyaluronan synthases in patients with Waldenstrom's macroglobulimenia., Adamia S, Crainie M, Kriangkum J, Mant MJ, Belch AR, Pilarski LM., Semin Oncol. April 1, 2003; 30 (2): 165-8.


Expression of hyaluronan synthase in intraocular proliferative diseases: regulation of expression in human vascular endothelial cells by transforming growth factor-beta., Suzuki K, Yamamoto T, Usui T, Suzuki K, Heldin P, Yamashita H., Jpn J Ophthalmol. January 1, 2003; 47 (6): 557-64.


'Piggy-back' transport of Xenopus hyaluronan synthase (XHAS1) via the secretory pathway to the plasma membrane., Müllegger J, Rustom A, Kreil G, Gerdes HH, Lepperdinger G., Biol Chem. January 1, 2003; 384 (1): 175-82.


Mammalian hyaluronan synthases., Itano N, Kimata K., IUBMB Life. October 1, 2002; 54 (4): 195-9.


Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients., Calabro A, Oken MM, Hascall VC, Masellis AM., Blood. October 1, 2002; 100 (7): 2578-85.


Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration., Itano N, Atsumi F, Sawai T, Yamada Y, Miyaishi O, Senga T, Hamaguchi M, Kimata K., Proc Natl Acad Sci U S A. March 19, 2002; 99 (6): 3609-14.


Functional molecular mass of a vertebrate hyaluronan synthase as determined by radiation inactivation analysis., Pummill PE, Kempner ES, DeAngelis PL., J Biol Chem. October 26, 2001; 276 (43): 39832-5.


Regulation of hyaluronan synthase gene expression in human periodontal ligament cells by tumour necrosis factor-alpha, interleukin-1beta and interferon-gamma., Ijuin C, Ohno S, Tanimoto K, Honda K, Tanne K., Arch Oral Biol. August 1, 2001; 46 (8): 767-72.


Reticular erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes., Tominaga A, Tajima S, Ishibashi A, Kimata K., Br J Dermatol. July 1, 2001; 145 (1): 141-5.


Up-regulation of putative hyaluronan synthase mRNA by basic fibroblast growth factor and insulin-like growth factor-1 in human skin fibroblasts., Kuroda K, Utani A, Hamasaki Y, Shinkai H., J Dermatol Sci. June 1, 2001; 26 (2): 156-60.


Regulation of renal proximal tubular epithelial cell hyaluronan generation: implications for diabetic nephropathy., Jones S, Jones S, Phillips AO., Kidney Int. May 1, 2001; 59 (5): 1739-49.


Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells., Recklies AD, White C, Melching L, Roughley PJ., Biochem J. February 15, 2001; 354 (Pt 1): 17-24.


Expression regulation of hyaluronan synthase in corneal endothelial cells., Usui T, Amano S, Oshika T, Suzuki K, Miyata K, Araie M, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. October 1, 2000; 41 (11): 3261-7.


Differentiation of mesothelioma cells is influenced by the expression of proteoglycans., Dobra K, Andäng M, Syrokou A, Karamanos NK, Hjerpe A., Exp Cell Res. July 10, 2000; 258 (1): 12-22.


Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: a molecular mechanism contributing to organ atrophy., Zhang W, Watson CE, Liu C, Williams KJ, Werth VP., Biochem J. July 1, 2000; 349 (Pt 1): 91-7.


Expression of human hyaluronan synthases in response to external stimuli., Jacobson A, Brinck J, Briskin MJ, Spicer AP, Heldin P., Biochem J. May 15, 2000; 348 Pt 1 29-35.


Synthesis of hyaluronan of distinctly different chain length is regulated by differential expression of Xhas1 and 2 during early development of Xenopus laevis., Köprunner M, Müllegger1 J, Lepperdinger G., Mech Dev. February 1, 2000; 90 (2): 275-8.


In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity., Yoshida M, Itano N, Yamada Y, Kimata K., J Biol Chem. January 7, 2000; 275 (1): 497-506.


The effect of mechanical strain on hyaluronan metabolism in embryonic fibrocartilage cells., Dowthwaite GP, Ward AC, Flannely J, Suswillo RF, Flannery CR, Archer CW, Pitsillides AA., Matrix Biol. December 1, 1999; 18 (6): 523-32.


Increased synthesis of hyaluronate enhances motility of human melanoma cells., Ichikawa T, Itano N, Sawai T, Kimata K, Koganehira Y, Saida T, Taniguchi S., J Invest Dermatol. December 1, 1999; 113 (6): 935-9.


Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy., Kaback LA, Smith TJ., J Clin Endocrinol Metab. November 1, 1999; 84 (11): 4079-84.


Expression of recombinant hyaluronan synthase (HAS) isoforms in CHO cells reduces cell migration and cell surface CD44., Brinck J, Heldin P., Exp Cell Res. November 1, 1999; 252 (2): 342-51.


Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties., Itano N, Sawai T, Yoshida M, Lenas P, Yamada Y, Imagawa M, Shinomura T, Hamaguchi M, Yoshida Y, Ohnuki Y, Miyauchi S, Spicer AP, McDonald JA, Kimata K., J Biol Chem. August 27, 1999; 274 (35): 25085-92.


Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells., Itano N, Sawai T, Miyaishi O, Kimata K., Cancer Res. May 15, 1999; 59 (10): 2499-504.


Expression pattern of a novel hyaluronidase during Xenopus embryogenesis., Hyde CE, Old RW., Mech Dev. April 1, 1999; 82 (1-2): 213-7.  


Hyaluronan synthase expression in bovine eyes., Usui T, Suzuki K, Kaji Y, Amano S, Miyata K, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. March 1, 1999; 40 (3): 563-7.


Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Gawantka V, Pollet N, Delius H, Vingron M, Pfister R, Nitsch R, Blumenstock C, Niehrs C., Mech Dev. October 1, 1998; 77 (2): 95-141.                                                            


The gene structure and promoter sequence of mouse hyaluronan synthase 1., Yamada Y, Itano N, Zako M, Yoshida M, Lenas P, Niimi A, Ueda M, Kimata K., Biochem J. March 15, 1998; 330 ( Pt 3) 1223-7.


Enzymological characterization of recombinant xenopus DG42, a vertebrate hyaluronan synthase., Pummill PE, Achyuthan AM, DeAngelis PL., J Biol Chem. February 27, 1998; 273 (9): 4976-81.


Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells., Sugiyama Y, Shimada A, Sayo T, Sakai S, Inoue S., J Invest Dermatol. February 1, 1998; 110 (2): 116-21.


Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family., Spicer AP, McDonald JA., J Biol Chem. January 23, 1998; 273 (4): 1923-32.              


Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis., Kumari K, Weigel PH., J Biol Chem. December 19, 1997; 272 (51): 32539-46.


An important developmental role for oligosaccharides during early embryogenesis of cyprinid fish., Bakkers J, Semino CE, Stroband H, Kijne JW, Robbins PW, Spaink HP., Proc Natl Acad Sci U S A. July 22, 1997; 94 (15): 7982-6.


Chromosomal localization of the human and mouse hyaluronan synthase genes., Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA., Genomics. May 1, 1997; 41 (3): 493-7.

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